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pDONR223_PIK3CG_WT

Plasmid

#81843

Purpose

Gateway Donor vector containing PIK3CG , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

PIK3CG (PIK3CG Human)

Use

Gateway entry vector

Mutation

E2G

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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Lenti-sgEp300#1/Cre

Plasmid

#173591

Purpose

Expresses a Ep300-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Ep300 (Ep300 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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pDONR223_PRDM1_WT

Plasmid

#81761

Purpose

Gateway Donor vector containing PRDM1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

PRDM1 (PRDM1 Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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Lenti-sgKdm6a#2/Cre

Plasmid

#173638

Purpose

Expresses a Kdm6a-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Kdm6a (Kdm6a Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgKdm6a#1/Cre

Plasmid

#173637

Purpose

Expresses a Kdm6a-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Kdm6a (Kdm6a Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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pGL3-Promoter-hPE(+)-Luc

Plasmid

#172003

Purpose

Luciferase Reporter for Human PTEN Enhancer PE - Forward Orientation

Depositor

Daniel Herranz

Article

Tottone et al Blood Cancer Discov. 2021 Jan;2(1):92-10

Insert

Human PE sequence (hPE)

Use

Luciferase

Expression

Bacterial and Mammalian

Promoter

SV40 Promoter

Available Since

July 8, 2021

Availability

Academic Institutions and Nonprofits only

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pDONR223_U2AF1_WT

Plasmid

#81954

Purpose

Gateway Donor vector containing U2AF1, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

U2AF1 (U2AF1 Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_TSC2_WT

Plasmid

#82281

Purpose

Gateway Donor vector containing TSC2, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

TSC2 (TSC2 Human)

Use

Gateway entry vector

Mutation

A210V; K704E; L1015M; I1649M

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pTRE-HRI-V5-IRES-BFP

Plasmid

#202435

Purpose

Lentiviral vector expression of HRI and TagBFP

Depositor

William Hahn

Article

Cervia et al Cancer Discov. 2023 Mar 1;13(3):766-795.

Insert

HRI (EIF2AK1 Human)

Use

CRISPR and Lentiviral

Tags

V5

Expression

Mammalian

Promoter

EF1alpha

Available Since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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pDONR223_U2AF1_p.S34F

Plasmid

#81358

Purpose

Gateway Donor vector containing U2AF1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

U2AF1 (U2AF1 Human)

Use

Gateway entry vector

Mutation

S34F

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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