Lenti-(BB)-hPGK-KRAB-dCas9-P2A-BlastR rs7903146-guide2
Plasmid
#125395
Purpose
CRISPR-mediated repression of human islet enhancer containing T2D-associated variant rs7903146 (TCF7L2 GWAS locus)
Depositor
Insert
KRAB-dCas9-2A-BlastR
Use
CRISPR and Lentiviral
Tags
HA
Expression
Mammalian
Mutation
Promoter
hPGK and U6
Availability
Academic Institutions and Nonprofits only