We narrowed to 12 results for: cas12a
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Pooled Library#209734PurposeCHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.DepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceJune 20, 2024AvailabilityAcademic Institutions and Nonprofits only
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CHyMErA AsCas12a Nuclease Optimization hgRNA Library
Pooled Library#209735PurposeCHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.DepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceJune 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
Inzolia library in pRDA_550
Pooled Library#209552PurposeThe human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.DepositorUseCRISPR and LentiviralAvailable SinceDec. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
Inzolia library in pRDA_052
Pooled Library#209551PurposeThe human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.DepositorUseCRISPR and LentiviralAvailable SinceDec. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
CHyMErA Exon-deletion hgRNA Library
Pooled Library#155200PurposeHybrid guide RNA library targeting human alternative cassette exons for deletion and disruptionDepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceSept. 2, 2020AvailabilityAcademic Institutions and Nonprofits only -
CHyMErA Paralog&Dual-targeting hgRNA Library
Pooled Library#155199PurposeHybrid guide RNA library targetings human paralog pairs and other protein-coding genes.DepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceSept. 2, 2020AvailabilityAcademic Institutions and Nonprofits only -
p11-5’_10xN_PAM-site3 (RTW572)
Pooled Library#160134PurposePlasmid library harboring a randomized 10nt PAM 5’ of target site 3. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)DepositorSpeciesSyntheticUseCRISPRAvailable SinceFeb. 8, 2021AvailabilityAcademic Institutions and Nonprofits only -
p11-5’_10xN_PAM-site4 (RTW574)
Pooled Library#160135PurposePlasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)DepositorSpeciesSyntheticUseCRISPRAvailable SinceFeb. 8, 2021AvailabilityAcademic Institutions and Nonprofits only -
pRG01-MCAP_MET
Pooled Library#123361PurposeCRISPR-Cpf1/Cas12a double knockout library. Targets 26 genes, chosen from analysis of human metastasis cohorts. It can be used to interrogate the genetic interactions driving metastasis.DepositorExpressionMammalianSpeciesSyntheticUseCRISPR and LentiviralAvailable SinceJune 10, 2019AvailabilityAcademic Institutions and Nonprofits only -
Humagne Set C
Pooled Library#172650PurposeSet C contains best-ranked guides 1 and 4.DepositorExpressionMammalianAvailable SinceNov. 10, 2021AvailabilityAcademic Institutions and Nonprofits only -
Humagne Set D
Pooled Library#172651PurposeSet D contains best-ranked guides 2 and 3.DepositorExpressionMammalianAvailable SinceNov. 10, 2021AvailabilityAcademic Institutions and Nonprofits only -
Mini-human AsCpf1-based human genome-wide knockout library
Pooled Library#130630PurposeKnockout library targeting 16,977 genes. Each gene is targeted by an AsCpf1(AsCas12a)-based array containing 3-4 guides concatenated in one vector.DepositorExpressionMammalianSpeciesHomo sapiensUseCRISPR and LentiviralAvailable SinceSept. 9, 2019AvailabilityAcademic Institutions and Nonprofits only