966 results

1. pAAV-Ef1a-fDIO-JRGECO1a (AAV1)

   Viral Prep

   #128317-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-Ef1a-fDIO-JRGECO1a (#128317). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO-JRGECO1a plasmid DNA. EF1a-driven, Flp-dependent expression of the biosensor jRGECO1a. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Patricia Jensen

   Promoter

   EF1a

   Tags

   None

   Available since

   March 18, 2024

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-hSyn-DIO-mCherry (AAV1)

   Viral Prep

   #50459-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn-DIO-mCherry (#50459). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-mCherry plasmid DNA. hSyn-driven, Cre-dependent mCherry-expression control. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available since

   Feb. 3, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pAAV_BiCHATe27_ChR2_mCherry (AAV PHP.eB)

   Viral Prep

   #213830-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pAAV_BiCHATe27_ChR2_mCherry (#213830). In addition to the viral particles, you will also receive purified pAAV_BiCHATe27_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the cholinergic neuron-targeting enhancer E27. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

   Promoter

   Tags

   mCherry

   Available since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-hDlx-GqDREADD-dTomato-Fishell-4 (AAV9)

   Viral Prep

   #83897-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hDlx-GqDREADD-dTomato-Fishell-4 (#83897). In addition to the viral particles, you will also receive purified pAAV-hDlx-GqDREADD-dTomato-Fishell-4 plasmid DNA. hDlx-driven expression of GqDREADD (hM3D) and nuclear localized dTomato (physically separate) for activation of interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   hDlx

   Tags

   dTomato

   Available since

   Nov. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (AAV5)

   Viral Prep

   #55645-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (#55645). In addition to the viral particles, you will also receive purified pAAV-hSyn Con/Fon hChR2(H134R)-EYFP plasmid DNA. Synapsin-driven, Cre-dependent and Flp-dependent channelrhodopsin-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Promoter

   Syn

   Tags

   EYFP (Cre- and Flp-dependent)

   Available since

   Dec. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA (AAV5)

   Viral Prep

   #20297-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA (#20297). In addition to the viral particles, you will also receive purified pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA plasmid DNA. Humanized channelrhodopsin H134R mutant fused to mCherry, driven by the EF1a promoter. Cre-dependent. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   EF1a

   Tags

   mCherry (Cre-dependent)

   Available since

   Feb. 15, 2018

   Availability

   Academic Institutions and Nonprofits only

7. pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 (AAV9)

   Viral Prep

   #100851-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 (#100851). In addition to the viral particles, you will also receive purified pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 plasmid DNA. Syn-driven jRCaMP1b calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Douglas Kim, GENIE Project

   Article

   Dana et al eLife. 2016 Mar 24;5. pii: e12727. doi:

   Promoter

   Syn

   Tags

   None

   Available since

   April 13, 2018

   Availability

   Academic Institutions and Nonprofits only

8. pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE (AAV5)

   Viral Prep

   #198516-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE (#198516). In addition to the viral particles, you will also receive purified pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE plasmid DNA. Ef1a-driven, Cre-dependent expression of the optimized opsin PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ofer Yizhar

   Article

   Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

   Promoter

   EF-1a

   Tags

   mScarlet

   Available since

   April 10, 2024

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE (AAV5)

   Viral Prep

   #125713-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE (#125713). In addition to the viral particles, you will also receive purified pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE plasmid DNA. Synapsin-driven, Cre-dependent expression of mosquito OPN3 rhodopsin in-frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ofer Yizhar

   Article

   Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

   Promoter

   Syn

   Tags

   mScarlet (Cre-dependent)

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pAAV_BiSSTe4_dTomato_nlsdTomato (AAV PHP.eB)

    Viral Prep

    #213944-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiSSTe4_dTomato_nlsdTomato (#213944). In addition to the viral particles, you will also receive purified pAAV_BiSSTe4_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the SST interneuron-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    dTomato

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

11. pAAV CD68-hM4D(Gi)-mCherry (AAV9)

    Viral Prep

    #75033-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV CD68-hM4D(Gi)-mCherry (#75033). In addition to the viral particles, you will also receive purified pAAV CD68-hM4D(Gi)-mCherry plasmid DNA. CD68-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced microglial inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Grace et al Proc Natl Acad Sci U S A. 2016 Jun 14;11

    Promoter

    CD68

    Tags

    mCherry

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

12. pENN.AAV.CamKII.HI.GFP-Cre.WPRE.SV40 (AAV9)

    Viral Prep

    #105551-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pENN.AAV.CamKII.HI.GFP-Cre.WPRE.SV40 (#105551). In addition to the viral particles, you will also receive purified pENN.AAV.CamKII.HI.GFP-Cre.WPRE.SV40 plasmid DNA. Expression of GFP-Cre from CamKII promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CaMKII

    Tags

    GFP

    Available since

    Aug. 2, 2018

    Availability

    Academic Institutions and Nonprofits only

13. AAV.CamKII.GCaMP6s.WPRE.SV40 (AAV9)

    Viral Prep

    #107790-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from AAV.CamKII.GCaMP6s.WPRE.SV40 (#107790). In addition to the viral particles, you will also receive purified AAV.CamKII.GCaMP6s.WPRE.SV40 plasmid DNA. CamKII-driven GCaMP6s calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CaMKII

    Tags

    None

    Available since

    May 15, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine (AAV8)

    Viral Prep

    #50455-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine (#50455). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine plasmid DNA. Synapsin-driven, Cre-dependent, inhibitory hM3D DREADD expression, with physically separate mCitrine expression for cell body labeling. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    mCitrine (Cre-dependent)

    Available since

    Sept. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-FLEX-tdTomato (AAV PHP.eB)

    Viral Prep

    #28306-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-FLEX-tdTomato (#28306). In addition to the viral particles, you will also receive purified pAAV-FLEX-tdTomato plasmid DNA. CAG-driven, Cre-dependent tdTomato expression control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Promoter

    CAG

    Tags

    tdTomato (Cre-dependent)

    Available since

    Feb. 28, 2018

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-EF1a-fDIO-Cre (AAV9)

    Viral Prep

    #121675-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-EF1a-fDIO-Cre (#121675). In addition to the viral particles, you will also receive purified pAAV-EF1a-fDIO-Cre plasmid DNA. EF1a-driven, Flp recombinase dependent expression of Cre recombinase. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Esteban Engel, Alexander Nectow

    Article

    Schneeberger et al Cell. 2019 Jun 24. pii: S0092-8674(19)30

    Promoter

    EF1a

    Tags

    None

    Available since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-hSyn-hChR2(H134R)-EYFP (AAV PHP.eB)

    Viral Prep

    #26973-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-hSyn-hChR2(H134R)-EYFP (#26973). In addition to the viral particles, you will also receive purified pAAV-hSyn-hChR2(H134R)-EYFP plasmid DNA. hSyn-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    EYFP

    Available since

    Sept. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

18. pGP-AAV-syn-jGCaMP8m-WPRE (AAV Retrograde)

    Viral Prep

    #162375-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-jGCaMP8m-WPRE (#162375). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP8m-WPRE plasmid DNA. Syn-driven expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    Syn

    Tags

    None

    Available since

    Aug. 4, 2021

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-hSyn-DIO-hM3D(Gq)-mCherry (AAV1)

    Viral Prep

    #44361-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-DIO-hM3D(Gq)-mCherry (#44361). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM3D(Gq)-mCherry plasmid DNA. Syn-driven, Cre-dependent, hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

    Promoter

    Syn

    Tags

    mCherry (Cre-dependent)

    Available since

    Feb. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

20. pGP-AAV-syn-jGCaMP8m-WPRE (AAV PHP.eB)

    Viral Prep

    #162375-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pGP-AAV-syn-jGCaMP8m-WPRE (#162375). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP8m-WPRE plasmid DNA. Syn-driven expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    Syn

    Tags

    None

    Available since

    June 21, 2024

    Availability

    Academic Institutions and Nonprofits only