963 results

1. pAAV-nEF-Con/Fon-ChR2-mCherry (AAV8)

   Viral Prep

   #137142-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-ChR2-mCherry (#137142). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-ChR2-mCherry plasmid DNA. nEF-driven, Cre and Flp-dependent expression of channelrhodopsin fused to mCherry for optogenetic activation.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   mCherry (Cre and Flp-dependent)

   Available since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

2. pAAV.Syn.GCaMP6s.WPRE.SV40 (AAV9)

   Viral Prep

   #100843-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.Syn.GCaMP6s.WPRE.SV40 (#100843). In addition to the viral particles, you will also receive purified pAAV.Syn.GCaMP6s.WPRE.SV40 plasmid DNA. Syn-driven GCaMP6s calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Douglas Kim, GENIE Project

   Article

   Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

   Promoter

   Syn

   Tags

   None

   Available since

   March 19, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-Syn-ChR2(H134R)-GFP (AAV Retrograde)

   Viral Prep

   #58880-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-Syn-ChR2(H134R)-GFP (#58880). In addition to the viral particles, you will also receive purified pAAV-Syn-ChR2(H134R)-GFP plasmid DNA. Humanized channelrhodopsin H134R mutant fused to GFP, under the control of the Synapsin promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Article

   Boyden et al Nat Neurosci. 2005 Sep . 8(9):1263-8.

   Promoter

   Syn

   Tags

   GFP

   Available since

   June 20, 2017

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-Syn-ChrimsonR-tdT (AAV5)

   Viral Prep

   #59171-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Article

   Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

   Promoter

   Syn

   Tags

   tdTomato

   Available since

   Feb. 7, 2018

   Availability

   Academic Institutions and Nonprofits only

5. pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 (AAV9)

   Viral Prep

   #100851-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 (#100851). In addition to the viral particles, you will also receive purified pAAV.Syn.NES-jRCaMP1b.WPRE.SV40 plasmid DNA. Syn-driven jRCaMP1b calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Douglas Kim, GENIE Project

   Article

   Dana et al eLife. 2016 Mar 24;5. pii: e12727. doi:

   Promoter

   Syn

   Tags

   None

   Available since

   April 13, 2018

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-hSyn-mScarlet (AAV8)

   Viral Prep

   #131001-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-hSyn-mScarlet (#131001). In addition to the viral particles, you will also receive purified pAAV-hSyn-mScarlet plasmid DNA. Synapsin-driven mScarlet control vector. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Marshel et al Science. 2019 Aug 9;365(6453). pii: scie

   Promoter

   Syn

   Tags

   mScarlet

   Available since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-CAG-DIO-NLS-mRuby3-IRES-eGtACR1-ST (AAV9)

   Viral Prep

   #109048-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CAG-DIO-NLS-mRuby3-IRES-eGtACR1-ST (#109048). In addition to the viral particles, you will also receive purified pAAV-CAG-DIO-NLS-mRuby3-IRES-eGtACR1-ST plasmid DNA. Cre-dependent expression of the anion channelrhodopsin GtACR1 fused to ER export signal and targeted to the neuronal soma and proximal dendrites, translated from an internal ribosomal entry site (IRES) following mRuby3 expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Hillel Adesnik

   Article

   Mardinly et al Nat Neurosci. 2018 Apr 30. pii: 10.1038/

   Promoter

   CAG

   Tags

   mRuby3

   Available since

   Feb. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-CaMKIIa-mCherry (AAV8)

   Viral Prep

   #114469-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-mCherry (#114469). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-mCherry plasmid DNA. CamKIIa-driven expression of mCherry. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   CaMKII

   Tags

   mCherry

   Available since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-hSyn-mCherry (AAV1)

   Viral Prep

   #114472-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn-mCherry (#114472). In addition to the viral particles, you will also receive purified pAAV-hSyn-mCherry plasmid DNA. Synapsin-driven mCherry control vector. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   Syn

   Tags

   mCherry

   Available since

   Oct. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

10. AAV pCAG-FLEX-EGFP-WPRE (AAV Retrograde)

    Viral Prep

    #51502-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV pCAG-FLEX-EGFP-WPRE (#51502). In addition to the viral particles, you will also receive purified AAV pCAG-FLEX-EGFP-WPRE plasmid DNA. CAG-driven, Cre-dependent EGFP expression control. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Promoter

    CAG

    Tags

    EGFP (Cre-dependent)

    Available since

    June 15, 2020

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-Ef1a-Con/Foff 2.0-GCaMP6F (AAV8)

    Viral Prep

    #137123-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-GCaMP6F (#137123). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-GCaMP6F plasmid DNA. EF1a-driven, Cre-dependent expression of GCaMP6f (inhibited in presence of Flp). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    None

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (AAV5)

    Viral Prep

    #162381-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (#162381). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    CAG

    Tags

    None

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-hSyn-Cre-P2A-dTomato (AAV9)

    Viral Prep

    #107738-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-Cre-P2A-dTomato (#107738). In addition to the viral particles, you will also receive purified pAAV-hSyn-Cre-P2A-dTomato plasmid DNA. hSyn-driven expression of Cre and dTomato (physically separate). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Rylan Larsen

    Promoter

    Syn

    Tags

    dTomato (physically separate, not a fusion protein)

    Available since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-EF1a-DIO-JEDI-2P-Kv-WPRE (AAV1)

    Viral Prep

    #179459-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-EF1a-DIO-JEDI-2P-Kv-WPRE (#179459). In addition to the viral particles, you will also receive purified pAAV-EF1a-DIO-JEDI-2P-Kv-WPRE plasmid DNA. EF1a-driven, Cre-dependent soma and AIS-localized expression of voltage indicator JEDI-2P. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Francois St-Pierre

    Article

    Liu et al Cell. 2022 Aug 16. pii: S0092-8674(22)00

    Promoter

    EF1a

    Tags

    cEGFP (Cre-dependent)

    Available since

    Aug. 23, 2022

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-hsyn-Jaws-KGC-GFP-ER2 (AAV5)

    Viral Prep

    #65014-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hsyn-Jaws-KGC-GFP-ER2 (#65014). In addition to the viral particles, you will also receive purified pAAV-hsyn-Jaws-KGC-GFP-ER2 plasmid DNA. hSyn-driven Jaws-GFP expression for optogenetic neural inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

    Promoter

    Syn

    Tags

    GFP

    Available since

    Feb. 7, 2018

    Availability

    Academic Institutions and Nonprofits only

16. pAAV.hSyn.iGluSnFR3.v857.GPI (AAV1)

    Viral Prep

    #178331-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn.iGluSnFR3.v857.GPI (#178331). In addition to the viral particles, you will also receive purified pAAV.hSyn.iGluSnFR3.v857.GPI plasmid DNA. Synapsin-driven, third generation glutamate sensor iGluSnFR3, variant 857. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Kaspar Podgorski

    Article

    Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4

    Promoter

    Tags

    None

    Available since

    May 16, 2023

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-hSyn-EGFP (AAV9 trial size)

    Viral Prep

    #50465-AAV9.T

    Purpose

    Ready-to-use AAV9 trial size particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

18. AAV-hSyn-Soma-jGCaMP8m (AAV1)

    Viral Prep

    #169257-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-hSyn-Soma-jGCaMP8m (#169257). In addition to the viral particles, you will also receive purified AAV-hSyn-Soma-jGCaMP8m plasmid DNA. Syn-driven expression of soma-targeted calcium sensor jGCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Marianne Fyhn

    Article

    Grodem et al Nat Commun. 2023 Feb 4;14(1):608. doi: 1

    Promoter

    Tags

    None

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

19. pGP-AAV-syn-FLEX-Volton2-ST-WPRE (AAV1)

    Viral Prep

    #172907-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-Volton2-ST-WPRE (#172907). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-Volton2-ST-WPRE plasmid DNA. Cre-dependent, Syn-driven expression of the voltage sensor Voltron2-ST containing a soma localization targeting sequence. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Abdelfattah et al Neuron. 2023 Mar 28:S0896-6273(23)00205-

    Promoter

    Syn

    Tags

    None

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

20. pAAV.CMV.PI.EGFP.WPRE.bGH (AAV PHP.eB)

    Viral Prep

    #105530-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV.CMV.PI.EGFP.WPRE.bGH (#105530). In addition to the viral particles, you will also receive purified pAAV.CMV.PI.EGFP.WPRE.bGH plasmid DNA. CMV-driven EGFP control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CMV

    Tags

    EGFP

    Available since

    Feb. 16, 2024

    Availability

    Academic Institutions and Nonprofits only