1,050 results

1. pAAV-CaMKIIa-hM3D(Gq)-mCherry (AAV1)

   Viral Prep

   #50476-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CaMKIIa-hM3D(Gq)-mCherry (#50476). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM3D(Gq)-mCherry plasmid DNA. CaMKIIa-driven hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Available Since

   Jan. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

2. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV5)

   Viral Prep

   #112677-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Promoter

   EF1a

   Tags

   mCherry (Cre-negative cells), EGFP (Cre-positive cells)

   Available Since

   Aug. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

3. AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (AAV PHP.eB)

   Viral Prep

   #214852-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (#214852). In addition to the viral particles, you will also receive purified AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) plasmid DNA. minBG-driven expression of CoChR-EGFP in striatal direct pathway medium spiny neurons (D1 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Allen Institute for Brain Science, Jonathan Ting

   Article

   Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

   Tags

   EGFP

   Available Since

   Nov. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-hSyn-dF-HA-KORD-IRES-mCitrine (AAV8)

   Viral Prep

   #65417-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-hSyn-dF-HA-KORD-IRES-mCitrine (#65417). In addition to the viral particles, you will also receive purified pAAV-hSyn-dF-HA-KORD-IRES-mCitrine plasmid DNA. hSyn-driven, Cre-dependent KORD expression with bicistronic mCitrine, for SALB-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Article

   Vardy et al Neuron. 2015 Apr 29. pii: S0896-6273(15)

   Promoter

   Syn

   Tags

   mCitrine

   Available Since

   Oct. 26, 2017

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (AAV9)

   Viral Prep

   #172922-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (#172922). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 plasmid DNA. hSyn-driven expression of jGCaMP8m in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Promoter

   Syn

   Available Since

   Aug. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-hsyn-GRAB_rDA1h (AAV9)

   Viral Prep

   #140557-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hsyn-GRAB_rDA1h (#140557). In addition to the viral particles, you will also receive purified pAAV-hsyn-GRAB_rDA1h plasmid DNA. Synapsin-driven expression of red fluorescent, high affinity dopamine sensor GRAB_rDA1h. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Yulong Li

   Article

   Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

   Promoter

   Syn

   Available Since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

7. AAV-CAG-jGCaMP8s-WPRE (AAV1)

   Viral Prep

   #179256-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from AAV-CAG-jGCaMP8s-WPRE (#179256). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8s-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8s. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   CAG

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pENN.AAV.CMVs.Pl.Cre.rBG (AAV5)

   Viral Prep

   #105537-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pENN.AAV.CMVs.Pl.Cre.rBG (#105537). In addition to the viral particles, you will also receive purified pENN.AAV.CMVs.Pl.Cre.rBG plasmid DNA. CMV-driven Cre. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CMV

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

9. pAAV.Syn.Flex.GCaMP6m.WPRE.SV40 (AAV9)

   Viral Prep

   #100838-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.Syn.Flex.GCaMP6m.WPRE.SV40 (#100838). In addition to the viral particles, you will also receive purified pAAV.Syn.Flex.GCaMP6m.WPRE.SV40 plasmid DNA. Syn-driven, Cre-dependent GCaMP6m calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

   Promoter

   Syn

   Available Since

   May 11, 2018

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-hSyn-GRAB_DA1h (AAV9)

    Viral Prep

    #113050-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-GRAB_DA1h (#113050). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_DA1h plasmid DNA. Synapsin-driven expression of GRAB-DA1h dopamine sensor in neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

    Promoter

    Syn

    Available Since

    Nov. 19, 2019

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-hSyn-JEDI-2P-Kv-WPRE (AAV9)

    Viral Prep

    #179463-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-JEDI-2P-Kv-WPRE (#179463). In addition to the viral particles, you will also receive purified pAAV-hSyn-JEDI-2P-Kv-WPRE plasmid DNA. hSyn-driven expression (soma and AIS-localized) of the genetically encoded voltage indicator JEDI-2P. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Francois St-Pierre

    Article

    Liu et al Cell. 2022 Aug 16. pii: S0092-8674(22)00

    Promoter

    Syn

    Available Since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-hDlx-GqDREADD-dTomato-Fishell-4 (AAV9)

    Viral Prep

    #83897-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hDlx-GqDREADD-dTomato-Fishell-4 (#83897). In addition to the viral particles, you will also receive purified pAAV-hDlx-GqDREADD-dTomato-Fishell-4 plasmid DNA. hDlx-driven expression of GqDREADD (hM3D) and nuclear localized dTomato (physically separate) for activation of interneurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

    Promoter

    hDlx

    Tags

    dTomato

    Available Since

    Nov. 2, 2020

    Availability

    Academic Institutions and Nonprofits only

13. pAAV.CAG.Flex.Ruby2sm-Flag.WPRE.SV40 (AAV1)

    Viral Prep

    #98928-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.CAG.Flex.Ruby2sm-Flag.WPRE.SV40 (#98928). In addition to the viral particles, you will also receive purified pAAV.CAG.Flex.Ruby2sm-Flag.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent expression of Ruby2sm-Flag spaghetti monster construct. Spaghetti monster constructs are not fluorescent ("dark") to allow full range of antibody staining. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Viswanathan et al Nat Methods. 2015 Jun;12(6):568-76. doi:

    Promoter

    CAG

    Tags

    mRuby2sm-Flag (spaghetti monster construct)

    Available Since

    April 20, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-S5E2-Gq-P2A-dTomato (AAV9)

    Viral Prep

    #135635-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Tags

    dTomato (physically separate, not a fusion protein)

    Available Since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

15. AAV-hSyn-Soma-jGCaMP8s (AAV Retrograde)

    Viral Prep

    #169256-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-hSyn-Soma-jGCaMP8s (#169256). In addition to the viral particles, you will also receive purified AAV-hSyn-Soma-jGCaMP8s plasmid DNA. hSyn-driven expression of soma-targeted calcium sensor GCaMP8s (more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Marianne Fyhn

    Article

    Grodem et al Nat Commun. 2023 Feb 4;14(1):608. doi: 1

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-hSyn-eNpHR 3.0-EYFP (AAV5)

    Viral Prep

    #26972-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSyn-eNpHR 3.0-EYFP (#26972). In addition to the viral particles, you will also receive purified pAAV-hSyn-eNpHR 3.0-EYFP plasmid DNA. hSyn-driven eNpHR 3.0-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    EYFP

    Available Since

    Feb. 14, 2018

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP (AAV8)

    Viral Prep

    #137153-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP (#137153). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of NpHR3.3-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre-dependent)

    Available Since

    April 8, 2021

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-hSynapsin-FLEX-soCoChR-GFP (AAV9)

    Viral Prep

    #107712-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin-FLEX-soCoChR-GFP (#107712). In addition to the viral particles, you will also receive purified pAAV-hSynapsin-FLEX-soCoChR-GFP plasmid DNA. Synapsin-driven, Cre-dependent somatic CoChR (soCoChR) fused to GFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Shemesh et al Nat Neurosci. 2017 Dec;20(12):1796-1806.

    Promoter

    Syn

    Tags

    GFP (Cre-dependent)

    Available Since

    Sept. 7, 2018

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-hSynapsin1-FLEx-axon-GCaMP6s (AAV5)

    Viral Prep

    #112010-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSynapsin1-FLEx-axon-GCaMP6s (#112010). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-FLEx-axon-GCaMP6s plasmid DNA. Synapsin-driven, cre-dependent axon targeted GCaMP6s calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Available Since

    Dec. 4, 2018

    Availability

    Academic Institutions and Nonprofits only

20. pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 (AAV8)

    Viral Prep

    #105540-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 (#105540). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 plasmid DNA. Expression of EGFP-Cre from hSyn promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    Syn

    Tags

    EGFP

    Available Since

    March 12, 2021

    Availability

    Academic Institutions and Nonprofits only