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We narrowed to 29 results for: HR2

Showing: 1 - 29 of 29 results
  1. New Viral Vectors - Winter 2025

    Type
    Blog Post
    ... viral prep AiP13755: pAAV-AiE0743m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3755) AAV-PHPeB...Control Gordon Fishell New viral prep pAAV_BiSSTe10_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiCHATe27_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiVIPe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiLAMP5e3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiPVe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiPVe3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...
  2. Channelrhodopsins with improved light sensitivity for minimally-invasive optogenetics

    Type
    Blog Post
    ...intensity than existing channelrhodopsins CoChR and/or ChR2(H134R). Designer channelrhodopsins paired with ...injections. When packaged in PHP.eB, ChRgers and ChR2(H134R) both reach the brain, but individual neurons...multiplicity of infection (MOI) makes it challenging for ChR2(H134R) to function because it’s lower conducence... a burst of light that could activate ChRger2 or ChR2(H134R) when they poked their nose into a hole in...what was seen with ChRger2 expressing mice, while ChR2(H134R) expressing mice did not have this self-stimulation...systemic delivery with PHP.eB compared to the existing ChR2(H134R).  In the second experiment, ChRger2 was delivered...the right M2 are activated, but mice that received ChR2(H134R) did not turn. Left-turning behavior in ChRger2...
  3. New and Upcoming Viral Vectors - December 2019

    Type
    Blog Post
    ...Fon hChR2(H134R)-EYFP 26975 AAVrg pAAV-CaMKIIa-hChR2(H134R)-mCherry 26976 AAV5 pAAV-hSyn-hChR2(H134R...packaged hChR2(H134R) plasmids from Karl Deisseroth’s lab, which includes pAAV-hSyn Con/Fon hChR2(H134R)...H134R)-mCherry 26973 AAVrg pAAV-hSyn-hChR2(H134R)-EYFP   Control AAV Control AAV allow researchers...
  4. New and Upcoming Viral Vectors - May 2020

    Type
    Blog Post
    ...AAV1 pAAV-CAG-FLEXFRT-ChR2(H134R)-mCherry Connie Cepko 83898 AAVrg pAAV-mDlx-ChR2-mCherry-Fishell-3 Gordon...Lentiviral preps for expressing SARS-CoV-2 proteins ChR2 for targeted expression DREADDs GFP dependent Cre...have expanded our AAV collection to include two new ChR2 constructs that allow for targeted expression. Plasmid...available in AAV1 for Flp-dependent expression of ChR2(H134R) bound to an mCherry reporter. We now also...AAVrg for plasmid 83898, which targets expression of ChR2 to forebrain GAB-ergic interneurons through the ...
  5. New and Upcoming Viral Vectors - September 2019

    Type
    Blog Post
    ... them! Controls pAAV-hSyn-hChR2(H134R)-EYFP (26973-AAVrg) pAAV-hSyn-hChR2(H134R)-mCherry (26976-AAV5)...(104496-AAVrg) Optogenetics pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (55645-AAV5)  Additional resources...
  6. The Materials Science of Optogenetics Experiments

    Type
    Blog Post
    ...      In the video above, Channelrhodopsin 2 (Chr2) has been expressed in the motor cortex of a mouse... light-gated cation channel, Channelrhodopsin 2 (ChR2), exists in several states: closed/light receptive.... If you deliver a continuous stream of photons, Chr2 will open but will not be given an opportunity to...
  7. Deciphering the Mysteries of Behavior with Viral Vectors

    Type
    Blog Post
    ...these neurons via the channel Channelrhodopsin 2 (ChR2) reduced glutamate transmission from the mPFC projections...Cre-dependent expression of  Channelrhodopsin 2 (ChR2), a modified receptor protein that activates neurons...
  8. Viral Vectors 101: Optogenetic Tools

    Type
    Blog Post
    ...controlling neuronal activity, channelrhodopsin-2 (ChR2), a blue light-activated cation channel, from the...opsin.      Figure 2: Diagram of excitatory (ChR2) activation by light showing ions flowing with the...
  9. New Viral Vectors - Spring 2025

    Type
    Blog Post
    ...Optogenetics Ofer Yizhar New viral tool pAAV-Ef1a-fDIO hChR2(H134R)-EYFP AAVrg Optogenetics Karl Deisseroth New...
  10. New Viral Vectors - Fall 2024

    Type
    Blog Post
    ...Optogenetics Karl Deisseroth New serotype pAAV-hSyn-hChR2(H134R)-EYFP AAV2 Optogenetics Karl Deisseroth New...
  11. Hot Plasmids - August 2020

    Type
    Blog Post
    ...hDlx-Flex-dTomato, mDlx-GCaMP6f, hDlx-GiDREADD-dTomato and mDlx-ChR2-mCherry. Find these AAVs at Addgene ...
  12. Optogenetics AAV Preps

    Type
    Collection
    ...collection. Opsin Excitatory Wild-type ChR2 ChR2/H134R soCoChR ChR2/other mutants Chronos, Chrimson, ChRmine... pACAGW-ChR2-Venus-AAV CAG ChR2 Venus Constitutive 1, 9 Karel Svoboda 58892 pAAV-GFAP104-ChR2-mCherry ... GFAP ChR2 mCherry Constitutive 5 Edward Boyden 83898 pAAV-mDlx-ChR2-mCherry-Fishell-3 Dlx ChR2 mCherry... 2.0-ChR2-mCherry nEF ChR2 mCherry Cre dependent 8 Karl Deisseroth 137144 pAAV-nEF-Coff/Fon-ChR2-mCherry... nEF ChR2 mCherry Flp dependent 8 Karl Deisseroth 137163 pAAV-nEF-Con/Foff 2.0-ChR2-EYFP nEF ChR2 EYFP...pAAV-RAM-d2TTA::TRE-ChR2-WPREpA TRE ChR2/H134R EYFP Constitutive 8 Yingxi Lin 100054 pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40... 9, rg* Gordon Fishell 135634 pAAV-S5E2-ChR2-mCherry nEF ChR2 mCherry Constitutive 1, 9, PHPeB Jordane...
  13. Penn Vector Core Partnership with Addgene

    Type
    Collection
    ...AAV-FLEX-rev-ChR2-tdtomato Optogenetics Scott Sternson AV-1-20071P 20071-AAV1 pACAGW-ChR2-Venus-AAV Optogenetics...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-1-26975 26975-AAV1 pAAV-CaMKIIa-hChR2(H134R)-...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-5-26975 26975-AAV5 pAAV-CaMKIIa-hChR2(H134R)-...pACAGW-ChR2-Venus-AAV Optogenetics Karel Svoboda AV-9-20297P 20297-AAV9 pAAV-EF1a-double floxed-hChR2(H134R...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-9-26975 26975-AAV9 pAAV-CaMKIIa-hChR2(H134R)-...pAAV-CaMKIIa-hChR2(E123A)-EYFP Optogenetics Karl Deisseroth AV-9-35506 35506-AAV9 pAAV-CaMKIIa-hChR2(E123A)-...pAAV-Ef1a-DIO hChR2(E123A)-EYFP Optogenetics Karl Deisseroth AV-9-35509 35509-AAV9 pAAV-Ef1a-DIO hChR2(E123T/...
  14. Caltech Systemic Capsids

    Type
    Collection
    ...pAAV-hSyn-hChR2(H134R)-EYFP Syn Activator ChR2 Deisseroth 20298 pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA...Cre-dependent ChR2 Deisseroth 127090 pAAV-CAG-DIO-ChR2(H134R)-eYFP CAG Activator, Cre-dependent ChR2 Gradinaru...213815 pAAV_BiSSTe10_ChR2_mCherry BiSSTe10 Activator ChR2 Fishell 213830 pAAV_BiCHATe27_ChR2_mCherry BiCHATe27...BiCHATe27 Activator ChR2 Fishell 213856 pAAV_BiVIPe4_ChR2_mCherry BiVIPe4 Activator ChR2 Fishell 213915 pAAV_BiLAMP5e3... pAAV_BiLAMP5e3_ChR2_mCherry BiLAMP5e3 Activator ChR2 Fishell 213937 pAAV_BiPVe4_ChR2_mCherry BiPVe4 Activator... Activator ChR2 Fishell 213941 pAAV_BiPVe3_ChR2_mCherry BiPVe3 Activator ChR2 Fishell 213945 pAAV_BiSSTe4...Dimidschstein 135634 pAAV-S5E2-ChR2-mCherry E2 regulatory element Activator ChR2 Dimidschstein 214846 AiP13755...
  15. Deisseroth INTRSECT Collection

    Type
    Collection
    ...Yes 55640 pAAV-Ef1a-dDIO hChR2(H134R)-EYFP Dre No 55639 pAAV-Ef1a-fDIO hChR2(H134R)-EYFP Flp Yes 126080...126080 pAAV-Ef1a-sCreDIO hChR2(H134R)-eYFP Scre No 126081 pAAV-Ef1a-vCreDIO hChR2(H134R)-eYFP Vcre No Dual...55645 pAAV-hSyn Con/Fon hChR2(H134R)-EYFP Cre AND Flp Yes 55644 pAAV-nEF Con/Fon hChR2(H134R)-EYFP Cre AND...pAAV-nEF Con/Foff hChR2(H134R)-EYFP Cre AND NOT Flp F3/F5 No 137163 pAAV-nEF-Con/Foff 2.0-ChR2-EYFP Cre AND...pAAV-hSyn Con/Foff hChR2(H134R)-EYFP Cre AND NOT Flp F3/F5 No 55649 pAAV-hnEF Coff/Fon hChR2(H134R)-EYFP Flp...pAAV-hSyn Coff/Fon hChR2(H134R)-EYFP Flp AND NOT Cre No 137139 pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP Cre AND...pAAV-nEF-Con/Foff 2.0-ChR2(ET/TC)-EYFP Cre AND Flp FRT/F5 Yes 137141 pAAV-nEF-Coff/Fon-ChR2(ET/TC)-EYFP Flp ...
  16. Brain Armamentarium

    Type
    Collection
    ...pAAV-AiE0743m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3755) Expression of ChR2(H134R)-EYFP in striatal...Fishell Viviana Gradinaru 213945-AAV1 pAAV_BiSSTe4_ChR2_mCherry AAV construct expressing mCherry-tagged... Fishell James M. Wilson 213945-PHPeB pAAV_BiSSTe4_ChR2_mCherry AAV construct expressing mCherry-tagged... Fishell Viviana Gradinaru 213941-AAV1 pAAV_BiPVe3_ChR2_mCherry AAV construct expressing mCherry-tagged...Gordon Fishell James M. Wilson 213941-PHPeB pAAV_BiPVe3_ChR2_mCherry AAV construct expressing mCherry-tagged... Fishell Viviana Gradinaru 213937-AAV1 pAAV_BiPVe4_ChR2_mCherry AAV construct expressing mCherry-tagged...Gordon Fishell James M. Wilson 213937-PHPeB pAAV_BiPVe4_ChR2_mCherry AAV construct expressing mCherry-tagged...
  17. Brain Initiative Collection

    Type
    Collection
    ... Gordon Fishell 83898-AAV1 pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain... Gordon Fishell 83898-AAV9 pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain...Gordon Fishell 83898-AAVrg pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion expression in forebrain...PHPeB pAAV-CAG-DIO-ChR2(H134R)-eYFP Cre-dependent AAV expression of humanized ChR2 (with H134R mutation... 135634-AAV1 pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical ... 135634-AAV9 pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical ...135634-PHPeB pAAV-S5E2-ChR2-mCherry AAV vector to drive the expression of ChR2-mCherry in PV cortical ...
  18. Retrograde AAV viral preps

    Type
    Collection
    ... pAAV-hSyn-hChR2(H134R)-EYFP Syn Activator Optogenetics Karl Deisseroth 28017 AAV-CAG-hChR2-H134R-tdTomato...pAAV-CaMKIIa-hChR2(H134R)-mCherry CamKII Activator Optogenetics Karl Deisseroth 55639 pAAV-Ef1a-fDIO hChR2(H134R... sensor Yulong Li 20297 pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA EF1a Activator, Cre-dependent...Optogenetics Karl Deisseroth 20298 pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA EF1a Activator, Cre-dependent...Optogenetics Karl Deisseroth 55645 pAAV-hSyn Con/Fon hChR2(H134R)-EYFP Syn Activator, Cre and Flp-dependent...Flp-dependent Optogenetics Karl Deisseroth 58880 pAAV-Syn-ChR2(H134R)-GFP Syn Activator Optogenetics Edward Boyden...Activator Optogenetics Edward Boyden 83898 pAAV-mDlx-ChR2-mCherry-Fishell-3 mDIx Activator Optogenetics Gordon...
  19. Optogenetics Guide

    Type
    Guide
    ...(nm) ChR2 Widely used light-gated cation channel from Chlamydomonas reinhardtii (CrChR2) 470 ChR2/H134R...light activated cation channel. ChR2 is preferred over ChR1 because ChR2 has higher conductance at physiological...dubia 460 C1C2 ChR1-ChR2 chimera 470 ChIEF, ChEF, ChD Engineered chimeras of ChR1 and ChR2; increased photocurrent...mouse line, such as for example the VGAT-ChR2 mouse, where ChR2 is expressed under the control of the vesicular...into the cell when stimulated. Channelrhodopsin-2 (ChR2), the first widely adopted optogenetic tool, is ...used variant with larger photocurrent compared to CrChR2 450 ChETA E123T mutation; faster kinetics but reduced...inactivation) ReaChR Red-activatable variant of CrChR2 590 Other Channelrhodopsins Name Description Peak...
  20. Optogenetics Plasmid Collection

    Type
    Collection
    ...widely used Channelrhodopsin-2 (ChR2) from Chlamydomonas reinhardtii . ChR2 is a membrane channel that opens...
  21. Immunology Research Plasmids and Resources

    Type
    Collection
    ... AMGL, AMGX AMH anti-Mullerian hormone MIF, MIS AMHR2 anti-Mullerian hormone receptor, type II AMHR, MISR2...receptor 1 CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f CRHR2 corticotropin releasing hormone receptor 2 CRFR2...hormone receptor 1 GPR24, MCH1R, MGC32129, SLC1 MCHR2 melanin-concentrating hormone receptor 2 GPR145,...hormone 2 TIP39 PTH2R parathyroid hormone 2 receptor PTHR2 PTHLH parathyroid hormone-like hormone HHM, MGC14611...ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I AMHR2 anti-Mullerian hormone receptor, type II AMHR, MISR2...
Showing: 1 - 29 of 29 results