We narrowed to 565 results for: PAC
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TypeBlog Post... (2) a complementary DNA sequence, and (3) a protospacer-adjacent motif (PAM) on the opposite strand. ...CRISPRi screen to identify endogenous genes that impact CGBE efficiency. In addition to using a new UNG...this strand is edited by base editors! PAM Protospacer-Adjacent Motif A short sequence that must be ...
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Fluorescent Protein Guide: Biosensors
TypeCollection...ready-to-use AAV preparations of select plasmids and AAV Packaged on Request for many more. Metal Ions Target Description...Dynamics in the Mitochondrial Matrix and Intermembrane Space with the GZnP2 Sensor. ACS Chem Biol. 2018 Jul 20...levels for imaging in live cells Fourth-generation epac-based FRET sensors for cAMP feature exceptional ...Description Gene/Insert Vector Type Eligible for Viral Packaging PI Return to Top Other Sensors and More Resources... -
Immunology Research Plasmids and Resources
TypeCollection...polypeptide 1 (pituitary) receptor type I PAC1, PACAPR, PACAPRI ADIPOQ adiponectin, C1Q and collagen domain...receptor 1 FLJ41949, HVR1, II, PACAP-R-2, RDC1, VAPC1, VIPR, VIRG, VPAC1, VPCAP1R VIPR2 vasoactive intestinal...cell types including T cells and B cells. It also impacts the development and function of innate immune cells...intestinal peptide receptor 2 FLJ16511, VPAC2, VPCAP2R XCL1 chemokine (C motif) ligand 1 ATAC, LPTN, LTN... -
Participate in the Pets of Addgene Scavenger Hunt
TypeBlog Post... year to give our lab and shipping teams enough space at HQ and for some of us, that means spending more...co-workers” have made their way onto our Slack workspace over the last year. Now, we’ve collected photos... -
Depositor Week 2020 is Happening Now. Join us!
TypeBlog Post...week to celebrate the scientists who make a big impact in open science. Depositors consistently contribute...depositor fun facts for a quick way to grasp the big impacts depositors have on science globally. *All data ... -
New Viral Vectors - Spring 2025
TypeBlog Post...titering. Our newest viral vector service, AAV Packaged on Request has seen a fantastic response from...our in-stock viral vectors or consider our AAV Packaged on Request service, which offers over 3,000 eligible... -
CRISPR Plasmids - RNA Editing
TypeCollection...change in RNA. dPspCas13b does not require a Protospacer Flanking Sequence (PFS), making it a very flexible...editing capabilities but are small enough to be packaged in AAV particles. Want more information on the... -
Grad School Advice Part 2: Building Community
TypeBlog Post...to younger graduate students Check Out Angela Depace's Talk on "Precision and Plasticity in Mentoring...studies developmental gene regulation with Dr. Angela DePace in the Department of Systems Biology, and he tweets... -
500,000 Plasmids Shipped and Counting!
TypeBlog Post...and moved to our packing area.Using the barcode system, the correct plasmids are packed into their boxes... -
Troubleshooting and Optimizing a Western Blot
TypeBlog Post...Running your transfer in the cold room or packing the box with ice packs can help keep the system cool, as can...overheating. Try running it in a cold room or putting ice packs in and/or around the gel box. If overheating remains... -
Making Career Development an Integral Part of the Science Training System
TypeBlog Post...the talent pipeline sets the world up for reduced impact of scientists and science. The pandemic has demonstrated...of priorities for pd|hub which include building capacity to identify the most effective practices and disseminating... -
Plasmid Collections
TypeCollection...Kits Kits are groups of plasmids that have been packaged together because they are intended for use as ...Initiative Collection Cell Migration Consortium Impact of Genomic Variation on Function (IGVF) Consortium... -
Optogenetics Plasmid Collection
TypeCollection...Insert Vector Type Promoter Eligible for Viral Packaging PI Return to top Optical Switch Plasmids Browse...Insert Vector Type Promoter Eligible for Viral Packaging PI Return to top Do you have suggestions for other... -
Bikard Lab - CRISPR Repression Collection
TypeCollection...CRISPR array coding for guide RNAs (diamonds) interspaced with CRISPR repeat motifs (squares), and also...concentration given relatively to the non‐targeting spacer measured by high‐throughput microscopy for a collection... -
Searchable and Sortable gRNAs for Your Next CRISPR Experiment
TypeBlog Post...Sequence Table. Disclaimer: The efficacy of gRNAs is impacted by the target location, target sequence, and model...multiple keywords that are separated by a single space to get even more specific. For example, to show ... -
Easing the Protein Purification Process with pCri
TypeBlog Post...yeast Pichia pastoris. The improved secretory capacities of these microbes make them useful for producing...difficult-to-fold proteins. In addition, P. pastoris has the capacity to glycosylate proteins and may recapitulate the... -
Spurred by COVID-19, Addgene Bridges Plasmid Sharing Between Academia and Industry
TypeBlog Post...role in fighting the pandemic could be even more impactful by reaching more scientists. Many members of the...past months, we’re excited to see our open sharing impact grow beyond COVID-19. But, we can’t do this alone... -
Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot
TypeBlog Post...relatively the same for quite a while and hadn’t kept pace with our growth over the last few years. Some of...elements and allowed our content to dictate the space. We wanted to comfortably tell our story, to get... -
Three Key Considerations for Precise Neuronal Targeting Using AAV Technologies
TypeBlog Post... consider. To tease apart how different neurons impact a certain output, neuroscientists have begun to...improve delivery by increasing transgene cargo capacity, enhancing anterograde transport efficiency, and... -
Increasing Your Work's Visibility with Addgene: Citation, Search, and Collections
TypeBlog Post...variety of metrics they can use to evaluate the impact of their work (H-index for instance), but these...the Addgene Blog Read How Notions of Scientific Impact Are Evolving Check out the Blog Post on Our Citations...