We narrowed to 724 results for: rel

...initiative to find a suitable partner, connect the relevant teams, coordinate implementation, and now must...conference calls and make sure to maintain these relationships by keeping in touch by email and social media...media (see the section on “Maintaining Relationships” below). Expand: Collaboration opportunities outside... fun. I just had to remember to approach the relationship with the perspective of my potential collaborators...generally asking for some advice and guidance. The relationships you establish in this way can, of course, lead...favors, but you should not go into a professional relationship expecting these things. In this context, I often...about and get started. You never know where the relationships you develop will lead! Read our blog post about...

...plasmid stability, reduced recombination relA or relA1 Relaxed phenotype, mutation eliminating stringent...blue/white screening. F- endA1 glnV44 thi-1 recA1 relA1 gyrA96 deoR nupG Φ80dlacZΔM15 Δ(lacZYA-argF)U169... for cloning repetitive DNA. endA1 glnV44 thi-1 relA1 gyrA96 recA1 mcrB+ Δ(lac-proAB) e14- [F' traD36 ...araD139]B/r Δ(codB-lacI)3 galK16 galE15 λ- e14- mcrA0 relA1 rpsL150(strR) spoT1 mcrB1 hsdR2(r-m+)  MG1655  ... ∆lacX74 galK16 galE15 e14-  Φ80dlacZ∆M15 recA1 relA1 endA1 nupG rpsL (StrR) rph spoT1 ∆(mrr-hsdRMS-mcrBC... recombine.  F- endA1 glnV44 thi-1 recA1 gyrA96 relA1 Δ(lac-proAB) mcrA Δ(mcrBC-hsdRMS-mrr) λ-  Stbl3...mcrBC-hsdRMS-mrr) recA1 endA1 gyrA96 gal-thi-1 supE44 λ-relA1 Δ(lac-proAB)/F' proAB+lacIqZΔM15 Tn10 (TetR) TOP10...

...planning you can do to build a bench mentor-mentee relationship and bring your best self to the training experience...plenty of articles on building successful mentor relationships, asking for mentor support, and choosing your...the research group). The bench mentor-mentee relationship is extremely important – without a good set ...mentor than your scientific mentor. Thus, this relationship will probably define your experience in the ...Luckily, you can do a lot to contribute to the relationship dynamic and set yourself up for success! Getting.... Preparation before bench work Are there any relevant papers you can read prior to the start of your...through the protocol mentally (or physically where relevant) and identify any gaps or questions you have, ...

... mentoring relationship, but if you don’t take this past the chatting stage you will rarely make any change...mentor. How do you make the most of this new relationship? Consider adding formality and active goal setting... setting to your mentoring relationships, so that you can reap rewards in the form of reaching career ...meetings and setting the direction in a mentoring relationship falls on the shoulders of the Mentee. A Mentor...progress over the course of an ongoing mentoring relationship (in a book or online). Mentee: Make a list of...secret of accountability To make a mentoring relationship really productive, the most important step you...SMART goals are Specific, Measurable, Attainable, Relevant, and Time-bound. It is a good idea to take larger...

...this, consider the cost of an accidental release. Science relies on popular support, which in turn depends...regions that don't have resident populations of the relevant mosquito species. Reproductive confinement involves... confinement strategies, but they should not be relied on exclusively because historical studies of pathogen...building candidate gene drives intended for eventual release should consider building an appropriate immunizing...mitigate the potential effects of an accidental release3. Which gene drive confinement strategies should... that trust more than an accidental gene drive release, which would represent proof positive that at least...powerful technology responsibly. An accidental release would be particularly dangerous for molecular biology...

... build the relationship in a non-awkward way?  7 ways to strengthen your new relationships Here are some...Relationships need nurturing. Perhaps you’ve met someone interesting at an event. Or, perhaps you have...contacts you have; it’s about building genuine relationships with people you care about knowing. How do you...some ways to go about strengthening a new relationship with authenticity and not discomfort: Invite the...meeting (in person or virtually) will make the relationship stronger.  If appropriate, invite them to speak...same people is often the easiest way to build relationships and strengthen them over time.  Things to ...important” or senior people. Focus on building relationships with peers and people around you naturally. ...

...demand for the related plasmid. Under such circumstances, we would observe this same correlation, but it wouldn...pulled the journals from 2005 to 2015 in areas most relevant to plasmids: Genetics & Heredity, Cell Biology...aggregated this much, you can see the 2013 ‘bump’ related to the CRISPR/Cas papers and Addgene deposits, ...Addgene, in contrast to other reasons for the correlation. However, determining this exactly is difficult... remaining difference caused by depositing the related plasmids with Addgene? Probably not all of it. ...still be controlled for. As an example, plasmid-related areas of science could be growing more quickly ...quickly which could also generate this type of correlation. But even with that caveat, it is still suggestive...

...familiar with a body of literature related to the topic. Finding reliable references and sorting out what...narrowing down your search and sorting the results (relevance, dates etc). The links for the titles can generally... you an overview of the topic and point you to relevant primary research articles. Then just start reading...should give a critical eye to all results in the relation to how they are supporting the conclusions. Look...key words and download what seems interesting or relevant. Harness the power of the Google search engine...Google Scholar will send you daily updates with relevant literature. Organizing the literature As a scientist... of useful papers. For many, this collection is purely electronic. Gone are the days of file cabinets ...

... Chen co-founded Addgene in 2004. They worked tirelessly to get Addgene from a concept to an up and running...job were important parts of team buidling - they relieved some of the pressure of start up life and maintained...“work hard, play hard.” Part of the reason we sincerely like spending time together is that when it’s ...employees. The teambuilding culture helps us build relationships and thereby work better together.I realize I...encourage everyone to make an effort to build relationships with their colleagues. It can be easy to get...done everything from kayaking, to field day, to relay triathlons, to 5Ks. Many of these examples we’ve...conversation to get people excited!    Laura Veckerelli is the Administrative and Operations Coordinator...

... more open to developing a relationship. The time to develop relationships is before you need them (well...academia often means that scientists-in-training rarely get the opportunity to learn about the myriad of...doing interesting things. I call this building relationships because networking has gotten a bad reputation...Scientists enjoy learning new things. Building new relationships is all about learning new things from other ...networking for a job connection with ongoing relationship building through Informational Interviews. Making...is always best to meet in person to develop relationships, but if it is not possible consider a phone ...

...Sacks "Neurologist Oliver Sacks examines the relationship between the human brain and music: how we perceive.... Sacks, Musicophilia includes case studies of relevant neurological atypicalities, including a patient...and fascinating, all without compromising on the relevant science."     - Randall Carter, Contracts Administrator...roles microbes play in our ecosystem, examining relationships between microbes and insects, mammals, and plants...Director of Quality Control Jonathan Strange & Mr. Norrell by Susanna Clarke "A quasi-historical/fantasy fiction... had a few reasons for launching this one. On a purely selfish level, I wanted to be challenged to read...responses ranged from “one of my favorite books” to “I barely got through it.”  To date, we’ve read 76 books ...

...base editors in vivo and achieved therapeutically relevant editing efficiencies in the mouse brain, liver...Physiol 2018. PubMed PMID: 30819783. Light up CreLite: a red-light inducible optogenetic tool for precision...lineage tracing Article contributed by Erin Sanders CreLite, designed by the Eisenhoffer lab, is a new tool...systems (ex: tamoxifen). As the name suggests, CreLite combines the Cre/lox system with optogenetics. ...studies. Eisenhoffer and his colleagues evaluated CreLite for cell tracing using the transgenic zebrafish...combination of fluorescent proteins expressed. CreLite-mediated recombination was found in both deep and...the breadth and versatility of this tool. Find CreLite at Addgene. Yen et al., bioRxiv 2019. DOI: 10.1101...

...NFIB- and NFIC-related human syndromes. As therapies are developed for specific NFI-related genetic disorders...formerly occupied by the Arg sidechain. Although not related to this rescue function, GdnHCl was approved by...binds to and inhibits a potassium channel, causing release of acetylcholine. Given its unique molecular biology...PubMed PMID: 9514755. Richard Gronostajski: NFI-related diseases of neural development Richard Gronostajski...VUSs will enable more accurate diagnosis of NFIX-related syndromes (Sotos-type 2 and Marshall-Smith) and...these will also allow better treatment of these related syndromes. Many thanks and best of luck to the...

...could be because there is no correlation or it could mean that the relationship is non-linear and you should...down the hall from you have in common? All of them rely on standard curves in their day-to-day work. Indeed...concentrations in food; and your friend the grad student relies on a standard in their bicinchoninic acid assay...of determination, R2. R2 is the square of the correlation between the actual values and the predicate values...fit and 0 indicating that there is no linear relationship between the observed and predicted values. This...Additional considerations When running assays that rely on a standard curve, it is critical that the unknown...

...racial bias from work being done today, is a nearly entirely separate effort from acknowledging its existence...dependencies  Take, for instance, a recent preprint released by the Boehm and Beroukhim labs at the Broad Institute...tumors, which can lead to new cancer targets and related biomarkers . Data from such screens are often uploaded...Unexpected results Their results showed 96 strongly correlated genetic dependencies that were clearly associated... they looked for a biological explanation, a relationship between the genetic dependencies they identified... ancestries. While there were some exciting relationships identified, 48% were found to be artificial,...bias into their experiments instead of a true correlation.   It turned out there was indeed a bias, and...

...re inefficient compared to CRISPR/Cas9 edits that rely on double strand DNA breaks. Due to this inefficiency...2018). TLDR: The ACE reporter from the Harris Lab relies on the restoration of a frame-shift in mCherry ...quantifies APOBEC-Cas9 efficiency in real-time, it relies on DSBs which is not ideal for monitoring single...APOBEC-Cas9 editisome complexes. The eGFP reporters rely on the correction of point mutations in eGFP that...base-editing activity The reporters mentioned above all rely on GFP fluorescence and cell sorting using FACS ...enriches for base editing events in vivo without relying solely on GFP (Katti et al., 2020). They named ...reporter system for base-editing events in vivo. As GO relies on the correction of a mutated start codon to initiate...

...membrane. Vampirovibrio chlorellavorus will not grown in culture alone and relies on its algae host for ...ant’s body. The fruiting bodies then rupture and release spores onto the forest below for the next unsuspecting...stumble upon. Vampire bacteria Vampirovibrio chlorellavorus is a predatory bacteria that attaches to the...adult worms develop in the digestive tract and release eggs in the bird feces, which get eaten by another... the predatory cyanobacterium Vampirovibrio chlorellavorus." PeerJ 3 (2015): e968. PubMed PMID: 26038723...

...difficult to consolidate every conceivable chromatin-related plasmid in a collection that grows on a daily basis... basis, the lists below provide a snapshot of relevant resources and a good jumping off point. The following... Yi Zhang Leonard Zon  You!     Chromatin-related genes with plasmids available from Addgene The ...directly on our website. In-exhaustive Chromatin-related genes with plasmids on Addgene.org AGO1 BRCA1...from Addgene Many articles reporting chromatin-related research describe the production of plasmids that...2018 Feb 13. pii: 1722491115. Addgene blog posts related to chromatin This is not the first Addgene blog...

... Sutton, located on the edge of London to gain relevant experience. I applied for this summer position...because I knew the tests worked and would produce a reliable result. This is not to say the role was without...left me optimistic that I would find a genetics related role soon after finishing my MSc. The masters program...large scale data analysis, as this is increasingly reliant on programming skills which are not my strong point...I had received all the training and experience relating to good manufacturing practice (GMP) and good ...downside to large commercial companies which are reliant on contracts with clients is that, when those contracts...

...and their successes. Although all mentorship relationships are valuable and highly recommended, a mentor...mentor creates a closer and more approachable relationship for the mentee, where (s)he feels truly understood...Scholars need strong proactive mentors who have relevant expertise and skills, positive disposition and..., mentors and mentees often developed close relationships with a level of sympathy that is difficult to...confidence. These improvements, combined with the relationships fostered through the IMP have motivated many...-Harvard Medical School, where she studies age-related macular degeneration. She is also a blogger who...