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TypeBlog Post... blood stream to commute to and invade multiple organs, and most importantly escape the immune mechanisms...environments for tumor cells spreading to other organs during metastasis. Evading Recognition Tumor cells...2002): 991-998. PubMed PMID: 12407406. 4. Weiner, George J. "Building better monoclonal antibody-based therapeutics...Ghana Modulate Cancer Signalling Resources on Addgene.org Check out Our Cancer Collection Pages Use the...
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Interview with Bart Newland, Addgene’s Newest Board Member
TypeBlog Post...of a lawyer can bring a new perspective to an organization. I'm used to thinking about the downstream results...how to manage them without them paralyzing an organization. I think these are things that I can bring to...that business experience and judgement to the organization and see how I can help. Q: What do you enjoy... -
Addgene’s Top 10 Blog Posts from 2014
TypeBlog Post...research with the community, so email us at blog@addgene.org if you are interested. Addgene's Most Popular...Plasmids 101: Origin of Replication By Kendall Morgan Save Time and Money by Making Your Own Competent...101: The Promoter Region – Let's Go! By Kendall Morgan Plasmids 101: Mammalian Vectors By Marcy Patrick... -
CRISPR-Cas14: a family of small DNA-targeting enzymes enabling high-fidelity SNP genotyping
TypeBlog Post...scientists to edit the genome of virtually any organisms on this planet, CRISPR-Cas systems were merely... to quickly detect the presence of infectious organisms (ex: SARS-CoV-2) and genetic mutations. By providing...Download our CRISPR cheat sheet Resources on Addgene.org Find the Cas14 plasmids here Checkout our CRISPR... -
Let There Be LITE Plasmids
TypeBlog Post...tissue. “The brain is such an amazing and dynamic organ,” Konermann explained. “It helps us adapt to influences...use is by no means limited to particular model organisms or cell types. “This tool is really flexible and... Kendall Morgan... -
Reflections and Looking Ahead
TypeBlog Post.... Even more remarkably, 1,160 labs from 522 organizations in 41 countries enriched our repository with...antibody characterization. Nature Protocols. https://doi.org/10.1038/s41596-024-01095-8 Kahn, R. A., Virk, H...biomedical research. eLife, 13, e100211. https://doi.org/10.7554/eLife.100211... -
Modulate the Activity of 17 Signaling Pathways with One Kit!
TypeBlog Post...growth, survival, and differentiation.” https://www.addgene.org/kits/sabatini-wood-cancer-pathway-orfs/ Finding...Technologies from 2015 Additional Resources on Addgene.org Find Other Kits for Your Research Find Pooled... Kendall Morgan... -
From our Table to Yours: An Inside Look at Lunch at Addgene
TypeBlog Post...sports, movies, and just about anything. As our organization grew, we continued this tradition. We now have...delicious) team building activity that is easy to organize. We’ll dedicate a post to these competitions in...Hack Days. During Hack Days, teams at Addgene will forgo their regular To-Do lists (other than emergency ... -
SciComm with the Experts at Science in the News Part 2
TypeBlog Post...Set up your own Science by the Pint series and organize evens where scientists can grab a beer and chat...institutional knowledge and continuity - two lead organizers on each program, one junior and one senior. ...For more info about starting your own SciComm organization and to learn about some of SITN's other initiatives... -
Celebrating Accomplishments in the Lab
TypeBlog Post...lab do for fun as a group? The Ellis Lab self-organizes cinema nights, game nights, and trips to eat out...flexibility and you aren’t locked into a schedule.” George Church comments on how he would go home in the ... Connie Cepko (Harvard Medical School), and Dr. George Church (Harvard Medical School) for taking the ... -
Spurred by COVID-19, Addgene Bridges Plasmid Sharing Between Academia and Industry
TypeBlog Post... happy to have the support of the following organizations to share materials more broadly to accelerate...to industry? Over the past 8 years, several organizations have made their plasmids available beyond academia...to industry, please reach out at techtransfer@addgene.org and we will initiate a conversation with you ... -
IBEX Knowledge-Base: A Data Resource for Multiplex Tissue Imaging
TypeBlog Post...reagent type, target species, target name, host organism, isotype, clone details, vendor, method, tissue...tissues. Nature Protocols, 17(2), Article 2. https://doi.org/10.1038/s41596-021-00644-9 Radtke, A. J., Kandov...Academy of Sciences, 117(52), 33455–33465. https://doi.org/10.1073/pnas.2018488117 More resources on the Addgene... -
Increasing Your Work's Visibility with Addgene: Citation, Search, and Collections
TypeBlog Post...collections pages, please shoot us an e-mail at help@addgene.org. We’d love to hear your feedback. Additional ...set of plasmids you’ve deposited with us. Don't forget to get yourself out there! Additional Resources...Inside Addgene Posts Additional Resources on Addgene.org Browse Our Special Collections Pages Suggest... -
9 Tips to Achieve Success in Academia
TypeBlog Post... Connie Cepko (Harvard Medical School), and Dr. George Church (Harvard Medical School) who took the time...helps when the time comes to work with full force. George Church 1. “Initial and sustained motivation is ...Thank you again to Connie Cepko, Tom Ellis, and George Church for answering our burning questions about... -
In Living Color: The Skinny on In Vivo Imaging Tools
TypeBlog Post...peering right through living animals to see their organs – a liver or brain, say, or maybe a tumor. They...for optical labeling and tracking of proteins, organelles, and living cells in a spatiotemporal manner,... Kendall Morgan... -
Understanding GPCR Signaling Using TRUPATH
TypeBlog Post...transducerome. Nat Chem Biol 16:841–849 . https://doi.org/10.1038/s41589-020-0535-8 Takeda S, Kadowaki S,...genome sequence. FEBS Letters 520:97–101 . https://doi.org/10.1016/s0014-5793(02)02775-8 Additional resources...Find other fluorescent biosensors Resources on Addgene.org Browse the catalog of fluorescent protein plasmids... -
Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight
TypeBlog Post...and space. Zebrafish have become a popular model organism because their larval stage lends itself well to...toolbox and the versatility of the zebrafish model organism, the Isacoff lab was able to link these cells ... Subscribe to the Addgene blog Resources on Addgene.org Learn about our ready-to-use viral service Find... -
Antibodies 101: Affinity Tags
TypeBlog Post...Humana Press. https://doi.org/10.1385/1-59259-301-1:99 Resources on Addgene.org Addgene antibodies ...Protein Science. John Wiley & Sons, Inc. https://doi.org/10.1002/0471140864 Fox, J. D., & Waugh, D. S. (... -
Antibodies 101: Fc Effector Functions
TypeBlog Post... responses. Cell Res 20, 34–50 (2010). https://doi.org/10.1038/cr.2009.139 Janda, A., Bowen, A., Greenspan...Function. Frontiers in Microbiology, 7. https://www.frontiersin.org/articles/10.3389/fmicb.2016.00022 Torres,...specificity. Trends in Immunology, 29(2), 91–97. https://doi.org/10.1016/j.it.2007.11.004 Xu Cao, et al. Promoting... -
Tips for Improving Your Next Manuscript
TypeBlog Post...Searching, Reading, & Organizing Write for the Addgene Blog Resources on Addgene.org Check out Our Revamped...straight to the point. 3. Engage the reader Scientists forget that the reader is not in their head. The scientist...