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  1. Antibodies 101: Secondary Antibodies

    Type
    Blog Post
    ... amounts or if the conjugated signaling molecule has a weak signal. For flow cytometry, secondary antibodies...introduction of antibody fragments, such as nanobodies, has introduced new options for increasing signal strength...
  2. Antibodies 101: Polyclonal Antibodies

    Type
    Blog Post
    ... - typically within 2-4 months. After the animal has the desired level of antibodies in its bloodstream...their batch to batch variability. Once an animal has undergone a terminal bleed to acquire all of its ...
  3. Viral Vectors 101: Gamma-Retroviral Packaging Systems

    Type
    Blog Post
    ...gamma-retroviruses) in cancer and stem cell research has prompted the development of multiple virus packaging...components found within the backbone. For example: pLXSN has the wild type LTR, an MCS for cloning X gene, an ...
  4. Viral Vectors 101: Viral Applications

    Type
    Blog Post
    ...hundred years ago. Since then, medical technology has changed a lot, but viruses have stuck around. Vaccine...been approved by the FDA, and this mode of delivery has a lot of clinical promise moving forward. What viruses...
  5. All in a Twist: dsRNA

    Type
    Blog Post
    ...immune response machinery of the host. This pathway has been clinically exploited for antiviral purposes ...deplete expression of proteins of interest. RNAi has even made it into agriculture as species-specific...
  6. Gendered Innovations: Why Does Sex of the Cell Matter?

    Type
    Blog Post
    ... human suffering and death. Doing research right has the potential to save lives and money. A 2014 analysis...physiologic or pathologic processes. Much progress has been made in this area in recent years, and you can...
  7. New Tool for Lineage Tracing: The ClonTracer Library

    Type
    Blog Post
    ...Vivo Pharmacology group at Novartis Oncology, Bhang has been working on using the ClonTracer library to monitor...allosteric inhibitors at Novartis. The ClonTracer library has been distributed all over the world and was recently...
  8. CRISPR 101: Non-Homologous End Joining

    Type
    Blog Post
    ...HDR, NHEJ is active throughout the cell cycle and has a higher capacity for repair, as there is no requirement...ends interfere with that step. Accordingly, NHEJ has a vast toolbox of processing factors, including polymerases...
Showing: 501 - 520 of 847 results