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We narrowed to 972 results for: arc

Showing: 561 - 580 of 972 results
  1. Academic vs. Industry Postdocs

    Type
    Blog Post
    ... essential part of being able to continue your research. As an academic postdoc, you’re often required... at once at the end of February or beginning of March, and the jobs are mixed into the general careers...developmental biology and is applying this towards researching neurodegenerative diseases.   Additional resources...
  2. xCas9: Engineering a CRISPR Variant with PAM Flexibility

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    Blog Post
    ...d like to modify. To tackle the PAM problem, researchers have engineered alternative Cas9s binding distinct...this case, NNGRRT and NNNNGATT, respectively. Researchers also engineered SpCas9 variants with alternative...fused to third generation cytidine base editor architecture (BE3) slightly improves NGG PAM editing efficiency...
  3. No Llamas Required - Synthetic Nanobodies Against Membrane Proteins

    Type
    Blog Post
    ...approach for treatment or prophylaxis of COVID-19. Researchers identified nanobodies that bind to coronavirus...sybody libraries in the form of mRNA for academic research. The template plasmids for generating your own...days. While the lab used this method for COVID-19 research, this protocol holds promise for developing treatments...
  4. Common Injection Routes in Mice

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    Blog Post
    ...drugs, DNA, viral vectors, and viruses. All researchers must go through the proper basic training prior...commonly administered through the tail vein — many researchers will simply refer to these as “tail vein injections...feeding tube can be flexible or metal, depending on researcher preferences. It sounds complicated but has a ...
  5. Twenty Years of Addgene Sharing: CRISPR

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    Blog Post
    ...depositing them in Addgene’s repository. Other researchers, eager to try this new technology, were quick...the CRISPR community?  Addgene exists to help researchers share useful tools, and as such, we’re always...collection, we’ve shared almost 300,000 plasmids with researchers all over the world. That’s an average of 27,272...
  6. Of Myc and Men

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    Blog Post
    ...devising their tagging strategy, another group of researchers was working on isolating monoclonal antibodies...identified oncogenes and was a target of intense research. Evan, et al. hoped that their new monoclonals...producing anti-Myc [9E10] as a recombinant antibody. Researchers first sequenced the variable domains of Myc1-...
  7. Hot Plasmids and Viral Preps - May 2021

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    Blog Post
    ...Jesse Bloom’s lab at the Fred Hutchinson Cancer Research Center developed a pooled plasmid library encompassing...plasmid encodes the mutated spike protein and a barcode, and is designed so that the SARS-CoV-2 spike RBD...encapsulating a single enzyme. Compared with previous research, which required protein compartments to co-localize...
  8. Interview: Nicola Patron on Plant Synthetic Biology, MoClo, and More

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    Blog Post
    ...hosts. I spoke with her about what motivates her research, the MoClo Kit she and Sylvestre Marillonnet share...and since we are making all the tools for plant research here and validating them, it made the most sense...academic in literature who gave a talk to the women’s research network here. She talked about the advantages ...
  9. Which Fluorescent Protein Should I Use?

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    Blog Post
    ...variants, and their relevant mutations, check out Marcy's post from last week on GFP. Additionally, many ... & pHTomato (pH sensors), HyPer (H2O2 sensor), ArcLight (voltage sensor), and iGluSnFr (glutamate sensor...to Our Guest Blogger! Gal Haimovich, PhD, is a research fellow in the lab of Prof. Robert Singer at Albert...
  10. CRISPR Plasmids - RNA Editing

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    Collection
    ... of RNA targeting with CRISPR. Browse, sort, or search the tables below for CRISPR plasmids designed for...
  11. AAVs in Retinal Gene Therapy

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    Blog Post
    ...delivered using this vector. For example, although researchers know that Usher Syndrome (a disease that results...encouraging. Importantly, a significant amount of basic research is being done to further improve the technology...Muzyczka N., 2014. AAV-Mediated Gene Therapy for Research and Therapeutic Purposes. Annu Rev Virol. 2014...
  12. Getting to Know Expansion Microscopy

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    Blog Post
    ...accessibility (Prakash K, et al. 2022). So what’s a researcher to do if they want to understand the ultrastructural...Since it arrived on the scene, ExM has helped researchers gain a deeper understanding of neuronal synapses... microscopy: principles and uses in biological research. Nat Methods 16:33–41. https://doi.org/10.1038...
  13. Transferable Skills Guide: Identifying Your Transferable Skills

    Type
    Blog Post
    ...technical expertise in a specific field. While searching for jobs and making connections, avoid falling...they’re seeking someone who has, to a t, all the research skills under your belt from your last job. You...managing inventories in the lab, or organizing a research project, one can assume that you’ve had to flex...
  14. Better Dyeing Through Chemistry & Small Molecule Fluorophores

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    Blog Post
    ...blogger, Luke Lavis, a Group Leader at the Janelia Research Campus, Howard Hughes Medical Institute. Chemistry...cell biologist can feel like a college student searching couch cushions for spare change, desperate to ...Lavis is currently a Group Leader at the Janelia Research Campus, Howard Hughes Medical Institute. He would...
  15. CRISPR Antimicrobials

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    Blog Post
    ... by antibiotic resistant bacteria. Even when researchers develop new antibiotics, the onset of resistance...’re turning the tables on the bacteria. Future research will show if this new strategy can help us win... on Addgene.org Find CRISPR Plasmids for Your Research Read Our CRISPR Guide Pages Find CRISPR gRNA Design...
  16. Fluorescent Proteins 101: Green Fluorescent Protein (GFP)

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    Blog Post
    ...derivatives are a staple in the lab. GFP is used in research across a vast array of biological disciplines ...protein and facilitating its widespread use in research. Many other mutations have since been introduced... Marcy Patrick...
  17. MAPK Plasmids

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    Collection
    ...biochemical signals. In collaboration with numerous research labs from around the globe, Addgene has assembled...
  18. CRISPR Plasmids - Bacteria

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    Collection
    ...Addgene's Empty gRNA Expression Vectors page and search the table for "Bacteria". Activate ID Plasmid Gene...
Showing: 561 - 580 of 972 results