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We narrowed to 1,010 results for: IGH@;

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Showing: 41 - 60 of 1010 results

  1. Resolute Plasmid Collection

    Type
    Collection
    ...the results, techniques, and reagents with the highest-possible quality of research output, RESOLUTE expects...production is used for assays and to generate antibody/ high-affinity ligands. Data is embedded in an integrated...Grixti, J., Kell, D. B., Mughal, F., Swainston, N., Wright-Muelas, M., Bohstedt, T., Burgess-Brown, N., Carpenter...

  2. TALEN Guide

    Type
    Collection
    ... are able to recognize their targets with fairly high specificity. Fifteen years of research has shown...TALe research has been swift. The incentives are high. Since ZF targets are confined to sequences composed...on specificity is on par with ZF arrays, if not slightly lower. Figure 2: Simplified representation of ...

  3. Lentivirus Plasmids

    Type
    Collection
    ...— contains packaging gene env This collection highlights popular second- and third-generation lentiviral...transgene expression. Contains intron that gives high expression. Didier Trono 12254 pWPI 2nd EF-1alpha...

  4. New Norepinephrine Indicators: nLightG and nLightR

    Type
    Blog Post
    ... nLightR. A, Structural models of nLightG (left) and nLightR (right) generated using ColabFold (Mirdita...indicators: nLightG and nLightR (Kagiampaki et al., 2023).     Figure 1: Properties of nLightG and nLightR...al., 2023. nLight nLight sensors are based on alpha-1a adrenergic receptor; nLightG contains circularly...norepinephrine. nLight is 28-fold more selective than GRABNE, with both nLightG and nLightR showing significantly...experimental design. Find nLight plasmids here! Next steps While nLightG and nLightR greatly expand the toolbox... both nLightG and nLightR, and may soon have a red tool which matches the sensitivity of nLightG. Many...images of HEK293T cells and neurons expressing nLightG or nLightR before/after application of NE (10 μM) and...

  5. Caltech Systemic Capsids

    Type
    Collection
    ...pAAV-EF1a-iCreV EF1a light-inducible recombinase iCreV Zeng 140136 pAAV-EF1a-iDreV EF1a light-inducible recombinase...recombinase iDreV Zeng 140137 pAAV-EF1a-iFlpV EF1a light-inducible recombinase iFlpV Zeng 164450 CN1851-rAAV-hI56i-minBglobin-iCre...

  7. TREAT-AD Plasmid Collection

    Type
    Collection
    ...resources for emerging targets in AD and creating high-quality, well-characterized lead molecules for prioritized...further translational investment. All resources and high-quality research tools are shared openly. Plasmids...

  8. DNA Service - Cloning Grade DNA

    Type
    Collection
    ...a variety of popular plasmids and backbones with high cloning potential. By making these plasmids available...spectrophotometer. Other methods of quantification may yield slightly different DNA concentrations. Can I directly transfect...

  9. Addgene Packaged on Request: Scope of Service

    Type
    Collection
    ...Addgene determines that our current queue is too high and we do not expect to meet the general turnaround...complete any additional customs documentation that might be required by your country for the import of biological...

  10. Adenovirus Plasmids

    Type
    Collection
    ...used for gene delivery due to their high packaging capacity, high efficiency in driving strong transient...

  11. Synthetic Biology - Overview

    Type
    Collection
    ...pre-assembled genetic circuits such as logic gates and higher level gene networks. Sensing and Signaling Browse...Efflux Pumps Voigt Lab Repressors , Terminators , Light Signaling , Sigma Factors , Resource Allocator and...

  12. Zinc Finger Consortium: Zinc Finger Arrays

    Type
    Collection
    ...Method Full Target Site (5' to 3') Left half-site Right half-site CACNA1F OZ507 and OZ508 OPEN OPEN gCGTGACCTCgctgatAAGAAGAGg...engineering of customized zinc-finger nucleases for highly efficient gene modification. Maeder ML et al. Mol...

  13. CRISPR Plasmids - Prime Edit

    Type
    Collection
    ... gRNA vectors suitable for prime editing are highlighted in the table below. Use the search bar to find...

  15. TALEN Plasmids and Kits

    Type
    Collection
    ...and C terminus and induces mutation at rates much higher than the parental vectors. pC-GoldyTALEN directs...obligate heterodimers that require cloning of left and right TALEN monomer proteins into opposite vectors. 37276...

  16. Empty Backbones - Choosing Your Perfect Plasmid Backbone

    Type
    Collection
    ...Advantages Representative Empty Backbones AAV High transduction efficiency, but do NOT integrate into... Retroviral backbones made by Addgene Adenoviral High transduction efficiency, but do NOT integrate into...

  17. Zhang Lab CRISPR Page

    Type
    Collection
    ...engineering using the CRISPR-Cas9 system. Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Nat Protoc . ... engineered CRISPR-Cas9 complex. Konermann S*, Brigham MD*, Trevino AE, Joung J, Abudayyeh OO, Barcena...

  18. Neurodegeneration Plasmid Collection

    Type
    Collection
    ...Parkinson's Richard Youle 23966 pTreTight-Htt94Q-CFP HTT CFP TREtight Huntington's Nico Dantuma 23971 ...Alzheimer's Gavin Wright 51643 APP-bio-His APP His, CD4 CMV Alzheimer's Gavin Wright 51811 PRNP-bio-His...PRNP-bio-His PRNP His, CD4 CMV Dementia Gavin Wright 53363 pCB268 APP Flag, HA, Myc CMV Alzheimer's Alexander Varshavsky...132389 AAVS1 CAG rtTA3 TauWT 2N4R-EGFP MAPT GFP TREtight Parkinson's, FTD Gerold Schmitt-Ulms 132393 AAVS1...AAVS1 CAG rtTA3 TauP301L 2N4R-EGFP MAPT GFP TREtight Parkinson's, FTD Gerold Schmitt-Ulms 133320 pHBS834...

  19. Light Sheet Fluorescence Microscopy

    Type
    Blog Post
    ...based on using a thin plane (sheet) of light generated by sunlight to observe single gold particles with...V= ventral Developments in light sheet fluorescence microscopy Modern light sheet fluorescence microscopy...out-of-focus reflected light by using a pinhole.  However, the excitation light excites all of the fluorophores..., there is a drop in image brightness with increasing depth caused by light scattering and absorption....of this century has seen some major advances in light microscopy, particularly related to the neurosciences....  One of these advances in microscopy has been light sheet fluorescence microscopy (LSFM). The underlying...a fluorescent sample and captured the reflected light using a different objective lens oriented perpendicular...

  20. Is this the right place for me? 8 tactics for choosing a lab

    Type
    Blog Post
    ...for many years (at a very low salary I might add). You have a right and responsibility to choose a lab where...Why is choosing the right lab such a big deal? It’s actually something you CAN choose and it will make...difference for your future career and life. You might see a lab head as choosing you, but in reality, ...communication before making this important decision. I’ll highlight some of these questions in the sections below....you are good at asking for and getting help, size might not be a big factor for you. Know who's boss You...considering a career at a small, teaching college you might want to consider less expensive, portable areas ...ownership" and author order PI lets lab members fight it out PI intervenes if there are interpersonal...
Showing: 41 - 60 of 1010 results