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...proteolytic site connecting the two proteins, thus releasing Cas9. Nanoblades can also deliver Cas9 variants...

...characterize the transcriptome. The first data release for CeNGEN is planned for August 15th, 2019. For...

...unlike other well-characterized Cas enzymes, which rely on multiple active sites. In addition, Casɸ has ...

...we use. Scientists utilize an array of tools that rely on DNA amplification and manipulation to produce...

...search and replace” genome editing technique that relies on a fusion enzyme of Cas9 nickase + reverse transcriptase...

...Beckman Coulter’s Biomek FXP. We had a previous relationship with Beckman Coulter and that certainly played...

... NYN PAMs, but with less efficiency and less reliability. Notably, the SpRY variant didn’t display higher...

... and minimal toxicity, including in clinically-relevant lines such as CAR-T cells. Plus, this method is...

... to the number of strands in the canonical beta-barrel structure. Most frequently, the proteins are split...

...HDR as the double-strand break repair pathway, relying instead on microhomology-mediated end-joining (...

...be indicated in the “Species Other” column. Relevant Mutations Indicate the amino acid change as ...

...containing FLEx technology. Read the genOway press release for more information. References: 1. Schnütgen ...

... and methylated states. Thus, this system is a reliable tool in reporting methylation status of these ...

...for Disease and Open Science: An Interview with Darrell Kotton Four Factors that Differentiate the Stem...

...four times in a 95% ethanol and dry ice bath to release the virus particles from the cells. Cell lysates...

...AAV5. AAV9 preps and more AAV1 versions will be released soon. Visualize axonal projections and putative...

...sybody selection platform can be found here and relevant plasmids are available in the Sybody Generation...

... molecular viewing software.   In reality, this rarely happens. But if you ever have an opportunity to...

...the tag, selectable marker, and connector to be released (Fig. 1, Step 2-3). Since donor plasmids of the...

.... If the solution is too cold, it will clump prematurely, and not spread out onto the plate. We test the...