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We narrowed to 1,049 results for: URE

Showing: 661 - 680 of 1049 results
  1. From our Table to Yours: An Inside Look at Lunch at Addgene

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    Blog Post
    ... a dish that features that ingredient. We just had a cook-off last week, and the featured ingredient was...Harry Potter-style.The shared lunches create a culture of openness and trust that comes from caring about...ll dedicate a post to these competitions in the future, and hopefully include some of our favorite winning...
  2. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

    Type
    Blog Post
    ...values with each element. We also set out to make sure the page looked clean, professional, and modern....our website, or in social media, we wanted to make sure our friend matched our core branding. Blugene needs... our values of community and sharing.  One big feature upgrade? Blugene now has a full expression. You...Addgene's new search tool Read more about other features of Addgene's website Resources on Addgene.org...
  3. Supporting Rare Disease Research with BeHeard 2017

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    Blog Post
    ...heart health. These are amazing advances that will surely save thousands if not millions of lives, but many...resources and promoting research for rare disease cures. Through their BeHEARD Award, the Rare Genomics ...better choose which genes and pathways to target in future small molecule screens. He plans to work with a...voice. Check back with Addgene often to learn of future rare disease research funding opportunities. References...
  4. Five Questions to Ask If You're Deciding Between a Master's or PhD Program

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    Blog Post
    ...wanted to be. But prior to graduate school, I wasn’t sure a master’s was a good decision. So how do you know...means to gain employment, so it’s important to make sure a masters helps you get a job you want. But how ...with master's have Job descriptions often fail to capture all of the responsibilities of a role, so it helps...questions in this blog post can help you start to figure out if a master’s is a good fit with your interests...
  5. Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation

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    Blog Post
    ...Rodríguez et al., 2011).  Genetics of SPARC Figure 1: SPARC and SPARC2 use the GAL4-UAS system along...sparse (S) labeling of the cell population. Figure 2: Dense (c), intermediate (d), and sparse (e) ...gene expression and clonal analysis in Drosophila. Nature Methods 9:47–55 . https://doi.org/10.1038/nmeth...projection-specific brain-wide reconstruction of single neurons. Nature Methods 15:1033–1036 . https://doi.org/10.1038/...
  6. Hot Plasmids and Viral Preps - July 2021

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    Blog Post
    ...Ashley Waldron Organoids are three-dimensional cultures that mimic aspects of organ morphology and physiology... an organoid model (Sun, et al. 2021).  Figure 1: Example schematic from the Organoid EasyTag ...targeted cells that can be used to generate organoid cultures with a modification of interest. While the authors...other Cas12a nucleases identified, functions at temperatures up to 43 °C and can be used for genome editing...
  7. Strengthening Foundations: Reflections on 2025 and What's Ahead for 2026

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    Blog Post
    ...their materials enables countless breakthroughs, ensures that scientific inquiry builds on prior discovery...scientific tools and computational approaches, we ensured that access to reliable plasmid information keeps...underrepresented research areas, we're working to ensure that when scientists need materials, Addgene can... blanca virus: from transformation to protein structure. Frontiers in plant science, 16, 1517321. https...
  8. Sensing Neuronal Dopamine

    Type
    Blog Post
    ... of the brain where DA quantitation is desired (Figure 1). The probe perfuses liquid, which causes the... the method is powerful and offers immediate measurements in a live animal that can be correlated to behavior...developed fluorescent-protein based DA sensors (Figure 2). The dLight1 dopamine sensor In 2018, Lin Tian...powerful new developments in the detection and measurement of neurotransmitters in various species and while...
  9. Bringing Sustainable Practices to the Lab: Recycling

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    Blog Post
    ...boxes). We get these boxes a lot when receiving temperature-controlled reagents. Expanded polystyrene will...company and it has to be packaging (no coated tissue culture plates, for example). Check the link for more details...or Axygen®, set up a bin or box in your tissue culture room for the wrappers and ship them back. Start...make a huge impact directly on waste, but also on culture. Encourage your workplace to become a leader in...
  10. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

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    Blog Post
    ...That includes keeping fees as low as possible to ensure that our materials are affordable but enough to...community-oriented values. Addgenies like the nonprofit company culture as well. We work every day to do a better job of... our core values. These accurately reflect our culture and outlook: Addgene increases productivity by...increase sharing in the community Addgene fosters a culture of respect, collaboration, and fun Addgene believes...
  11. Fluorescent Proteins 101: Fluorescent Biosensors

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    Blog Post
    ... first need to decide the best way to track or measure the process you’re interested in. Depending on ...examine, i.e. for an enzymatic reaction, you could measure consumption of a substrate OR production of a product...molecule biosensors Addgene has many sensors that measure the concentration of small molecules like arabinose...withstand a particular solute concentration or temperature? For further advice, see our posts on how to ...
  12. Antibodies 101: Affinity Tags

    Type
    Blog Post
    ... visualization. However, due to the nature of the size, structure, and other qualities of each tag class...individually isolate a protein, there must be a special feature about that protein that no other protein in the...for an extra clean up step of the tag – a handy feature. If you decide not to cleave the GST tag after/...
  13. An Addgene Co-op: The Intersection of Fun, Friendship, and Work

    Type
    Blog Post
    ... lunch. There was something so special about her pure interest and curiosity to understand my work and...making of this photo!  Here, I was also given a mixture of support and independence that allowed me to ...on content strategy. I really believe that the culture at Addgene cultivates trust between coworkers and... more confident in myself, my abilities, and my future - something I didn’t expect from a co-op experience...
  14. Cellosaurus: A Cell Line Information Database

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    Blog Post
    ...for helpful information on the known features and relevant literature, or to decide which line is best for...cell line collections websites and catalogues Literature searches utilizing Google Scholar alerts and ...as commonly misidentified lines. Browsing this feature to know if your lines may be especially vulnerable...
  15. Running for Rare Disease, Running for FOP, Running for AJ

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    Blog Post
    ...very painful FOP flare ups. Eventually, without a cure, AJ will begin losing mobility and not be able to...play like the other kids his age. A potential FOP cure But, there is HOPE. FOP is a genetic disease typically...solutions to treat rare diseases like FOP until a cure is available. Addgene and AJ's Avengers This year...knowledge of FOP, it’s biological causes, and potential cures. We encourage any researchers working on ACVR1 or...
  16. Networking and Inspiring Young Scientists at Freshers Fairs

    Type
    Blog Post
    ...young scholars across Europe get introduced to the cultures and opportunities available to them at university...to students. Freshers fairs are also where many future scientists are introduced to the biology and chemistry...talks by prominent scientists, including Nobel Laureates, who speak about their work and current, trending...positions both inside and outside academia. Inspiring future scientists At Addgene, we’re incredibly glad to...
  17. The Golden Stopwatch Award: Recognizing Facilitators of Research

    Type
    Blog Post
    ...Updated April 21, 2020 Picture this: you’re a busy scientist anxiously awaiting the arrival of the newest...signs each agreement just once, covering nearly all future requests/deposits. This reduces the processing ...between a TTO and Addgene, whose terms apply to all future deposits of materials with Addgene Master Reception...between a TTO and Addgene, whose terms apply to all future materials requests from Addgene MTA: material transfer...
  18. Antibodies 101: Epitope Tags

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    Blog Post
    ...readthrough mitigation. Nature. (2016) 534, 719-723. DOI: 10.1038/nature18308   Additional resources on...are unreliable for a variety of reasons (Baker, Nature). Tagging your protein allows you access to a ...Reproducibility crisis: Blame it on the antibodies. Nature (2015) 521, 274-276 DOI: 10.1038/521274a Arribere...
  19. Antibodies 101: Chimeric Antibodies

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    Blog Post
    ... both targets in your specimen. You scour the literature and find an ideal antibody against Protein A ...distinguish between your two targets.    Figure 1: In the isotype conversion process the variable...successfully visualize both proteins.     Figure 2: Two primary antibodies with the same isotype... the anti-Protein B antibody (Fig. 3)    Figure 3: Recommended secondary antibodies for rat IgG1...
  20. Natural or synthetic? How Addgene’s dataset reveals trends in biological innovation

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    Blog Post
    ...synthesis. They published their results in a paper in Nature Communications announcing a new bioinformatics ...good predictors because they are just that: rare. “Nature has many genes where there are not rare codons ...source genes from farther away in the tree of life." Nature communications 9.1 (2018): 4425. PubMed PMID: 30356044...to predict the lab-of-origin of engineered DNA." Nature communications 9.1 (2018): 3135. PubMed PMID: 30087331...
Showing: 661 - 680 of 1049 results