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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 938 results for: mpl

Showing: 701 - 720 of 938 results

  5. Predicting Adverse Reactions to Monoclonal Antibody Drugs

    Type
    Blog Post
    ... binding affinity to major histocompatibility complexes (MHC class I and II).  There are multiple algorithms...approach The in silico approach cannot replicate the complexity of antigen processing events that take place ...

  6. Trading Spaces - Visiting Scientist Edition

    Type
    Blog Post
    ...from a month to a year. The researcher remains employed by their home institute, meaning the host university...and a priority list of experiments you hope to complete. Share this plan with your host prior to arrival...

  7. Hot Plasmids - January 2023

    Type
    Blog Post
    ...JA. Precise transcript targeting by CRISPR-Csm complexes. Nat Biotechnol. 2023 Jan 23. doi: 10.1038/s41587...antibodies allows you to use them in parallel to help amplify your signal - giving you the benefit of a polyclonal...

  10. Choosing Your Fluorescent Proteins for Multi-Color Imaging

    Type
    Blog Post
    ... proteins should be separated by 50-60 nm. For example, CFP (ex 430 nm / em 474 nm) and YFP (ex 514 nm...protein of interest has a similar spectrum. For example, here's a screenshot from the Chroma Spectra Viewer...

  12. Communicating Your Science With Help From ComSciCon

    Type
    Blog Post
    ...an interview setting, this means persuading an employer that your past work has prepared you to contribute...audience and ask for their feedback before you complete your work. If you’re giving a public talk, ask...

  13. Why and how to start studying chromatin (with Addgene's help)

    Type
    Blog Post
    ...interact with each other. Chromatin regulation is complex and influences--directly or indirectly--many other...phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling...

  14. How Addgene Creates Content

    Type
    Blog Post
    ... look at how we create this content, using the example of our Antibody Guide, which was published alongside...require updating or retiring. CRISPR/Cas9, for example, has gone through rapid change in the past few ...

  15. Antibodies 101: Isotypes

    Type
    Blog Post
    ...portion of different antibody isotypes. Binding to complement system proteins, which can initiate a cascade... next to a different constant domain gene. For example if a B cell switches to producing IgE antibodies...

  16. OCaMP: A New Calcium Indicator for Neural Imaging

    Type
    Blog Post
    ...jRGECO1a and jRCaMP1a are widely used as well. To complement these tools, we recently developed a new orange...cell types at once using existing indicators. For example, you might want to use OCaMP to monitor Ca2+ signals...

  17. Fluorescent Proteins 101: Luciferases

    Type
    Blog Post
    ...chemical reaction takes place. Figure 2: Simplified chemical reaction catalyzed by luciferase, releasing... proteins to be visualized simultaneously. Complementation systems for examining protein-protein interactions...

  18. CasPEDIA: A Functional Classification of Cas Enzymes

    Type
    Blog Post
    ... the cis and trans activity of each entry. For example, SpyCas9a (one of the most frequently used Cas ... an advanced search option. For the former, you simply type in identifier keywords (Cas name, RefSeq ID...

  19. Viral Vectors 101: Types of viruses

    Type
    Blog Post
    ...that use reverse transcriptase to synthesize complementary DNA copies of their genome upon infecting a ... These viruses have a cargo capacity of ~ 8 kb, ample room for most experimental needs, and can transduce...

  20. Viral Vectors 101: Viral Applications

    Type
    Blog Post
    ...shRNAs are short RNA sequences which target complementary mRNA sequence for degradation. Viral introduction...targeting an exon in your gene of interest, for example. Some customization is required, but many viral...
Showing: 701 - 720 of 938 results