Prime Editing: Adding Precision and Flexibility to CRISPR Editing
Type
Blog Post
...Temporarily inhibiting this complex may allow time for 5′ flap exonucleases and DNA ligases to act first.
PE4... optimized enzyme can be used with any of the PE2-5 approaches, sometimes referred to as PE2max, PE3max...with twin prime editing. Nature Biotechnology, 40(5), 731–740. https://doi.org/10.1038/s41587-021-01133...post was originally written by Jennifer Tsang in October 2019 and updated by Emily P. Bentley in December...