Adeno-associated virus (AAV) Guide
Type
Guide
...AAV2/5 indicates a virus containing the genome of serotype 2 packaged in the capsid from serotype 5. Use...comparison. Duan D, Yue Y, Engelhardt JF. Mol Ther. 2001 Oct;4(4):383-91. PubMed . Return to Top...efficiency, as well as alter tropism. For example, AAV2/5 targets neurons that are not efficiently transduced...first with a 3’ splice donor and the second with a 5’ splice acceptor. When these viruses co-infect a cell...much less efficient than with a single AAV virus (∼5%). Another technique for increasing packaging capacity...pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after...