Supporting Rare Disease Research with the 2020 BeHEARD Awards
Type
Blog Post
...-, and intensity-based signaling biosensors to monitor intracellular signaling,” says Hébert. Previous...Prakash!
Terry Hébert: How GNB1 mutations affect signaling pathways
G protein-coupled receptors (GPCRs) detect...molecules outside of the cell and translate those signals into cellular responses. For example, GPCRs and...proteins, with an emphasis on oligomerization, signalling complex assembly, and localization to the nucleus...knowledge of GNB1 disorder by understanding affected signaling pathways and how they lead to neurological phenotypes...GNB1 mutations, the lab hopes to capture the signalosome of different receptors upon stimulation. “To ...