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We narrowed to 861 results for: SOM

Showing: 821 - 840 of 861 results

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New Optimized Genome-wide CRISPRko, CRISPRi, and CRISPRa Libraries

Type

Blog Post

...activation domain (CRISPRa) to regulate gene expression. Some CRISPR libraries contain many sgRNAs per gene to...
Don’t FRET: Bimolecular Fluorescence Complementation Makes Visualizing Protein-Protein Interactions Easy

Type

Blog Post

...careful selection of FP fragments and, preferably, some information about the structures of the tested PIPs...
AAVs CREATed for Gene Delivery to the CNS and PNS

Type

Blog Post

...inducer virus. Additionally, this system is less cumbersome than brainbow, another method for multi-color...
Lentiviral Vector Uses and Overview

Type

Blog Post

...promoter. Although safer, this system may be more cumbersome to use and lead to lower viral titers due to ...
CRISPR Antimicrobials

Type

Blog Post

... that CRISPR, the bacterial immune system, may someday be used to target the hardest-to-kill bacteria....
Cpf1: A New Tool for CRISPR Genome Editing

Type

Blog Post

... a different nuclease could potentially overcome some of Cas9’s shortcomings - namely its blunt double...
CRISPR 101: Targeting RNA with Cas13a (C2c2)

Type

Blog Post

...cells The Zhang lab made the exciting discovery that some Cas13a orthologs can function in mammalian and plant...
Deciphering the Mysteries of Behavior with Viral Vectors

Type

Blog Post

...mysteries of behavior. We’ve previously discussed some of the general considerations for performing behavioral...
New Tools Enable CRISPRa for Neuroscience Applications

Type

Blog Post

...sequenced. Guide RNAs targeting several known and some unknown regulators of neuronal differentiation were...
Antibodies 101: Immunoprecipitation

Type

Blog Post

...References: Björck L, Kronvall G (1984) Purification and some properties of streptococcal protein G, a novel IgG-binding...
Rett Syndrome: A History of Research and Therapeutic Outlooks

Type

Blog Post

...research, the role of the MECP2 gene, and highlights some of the latest breakthrough therapeutic approaches...
Overcoming the AAV Size Limitation for CRISPR Delivery

Type

Blog Post

... While finding smaller Cas9 orthologs works for some applications, it doesn’t eliminate the need to deliver...
Finding nucleic acids with SHERLOCK and DETECTR

Type

Blog Post

...system SHERLOCKv2 for SHERLOCK version 2. Here are some of the improvements: SHERLOCKv2 uses far less primer...
Plasmids 101: Plasmid Incompatibility

Type

Blog Post

...suggest that the late replication that occurs for some types low copy plasmids during cell division simply...
New Acoustic Reporter Genes: Ultrasound Imaging of Gene Expression

Type

Blog Post

...poorly at body temperature (37oC) and were too burdensome to express in situ. As a result, they had to ...
Hot Plasmids: Fall 2024

Type

Blog Post

...Every few months, we highlight some of the new plasmids, antibodies, and viral preps in the repository...
Twenty Years of Sharing: Addgene's Viral Vector Service

Type

Blog Post

...complexity of effectively deploying them in the lab somewhat mirrors the complexity of understanding their ...
CRISPR 101: Which Cas9 Do I Choose for My CRISPR Experiment?

Type

Blog Post

...modifications Site-specific deletions and knockouts Some experiments may require the introduction of a mutation...
Tips for CRISPR Gene Editing in Mice

Type

Blog Post

...of writing many of the specifics surrounding why some gRNA’s work better than others remain unknown, but...
Tips for Using FRET in Your Experiments

Type

Blog Post

...easy technique, but it is very important to follow some simple rules to avoid common pitfalls and to use...

Showing: 821 - 840 of 861 results

Results per page:

New Optimized Genome-wide CRISPRko, CRISPRi, and CRISPRa Libraries

Don’t FRET: Bimolecular Fluorescence Complementation Makes Visualizing Protein-Protein Interactions Easy

AAVs CREATed for Gene Delivery to the CNS and PNS

Lentiviral Vector Uses and Overview

CRISPR Antimicrobials

Cpf1: A New Tool for CRISPR Genome Editing

CRISPR 101: Targeting RNA with Cas13a (C2c2)

Deciphering the Mysteries of Behavior with Viral Vectors

New Tools Enable CRISPRa for Neuroscience Applications

Antibodies 101: Immunoprecipitation

Rett Syndrome: A History of Research and Therapeutic Outlooks

Overcoming the AAV Size Limitation for CRISPR Delivery

Finding nucleic acids with SHERLOCK and DETECTR

Plasmids 101: Plasmid Incompatibility

New Acoustic Reporter Genes: Ultrasound Imaging of Gene Expression

Hot Plasmids: Fall 2024

Twenty Years of Sharing: Addgene's Viral Vector Service

CRISPR 101: Which Cas9 Do I Choose for My CRISPR Experiment?

Tips for CRISPR Gene Editing in Mice

Tips for Using FRET in Your Experiments

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