We narrowed to 961 results for: ARC
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TypeBlog Post...γ-retroviruses (gamma-retroviruses) in cancer and stem cell research has prompted the development of multiple virus... 3’ LTR and are primarily used in gene therapy research to reduce promoter interference and/or drive high...Cycle Popular Retroviral Vectors and Their Use in Research More resources on addgene.org Addgene Protocols...
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Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog Post...base editors for your research Read our CRISPR guide Find plasmids for your research ...compatible with all Cas9 and Cas12 homologs that the researchers tested, including SpCas9, SaCas9, LbCas12a, enAsCas12a... -
GPCRs: How Do They Work and How Do We Study Them?
TypeBlog Post...GPCRs. This collection, called TRUPATH, allows researchers to identify specific G proteins activated by ...s still a lot to learn about GPCR signaling, researchers in the meantime have developed GPCRs for chemogenetic...chemogenetics guide Find chemogenetics plasmids for your research ... -
7 Tips to Secure a STEAM Internship This Summer
TypeBlog Post...-level positions right out of college. Prior to March 2020, internships were a fiercely competitive endeavor...applying to several opportunities. In an age of scarcity, the rational human being will tend to clinch ...out other tools and resources for early career researchers Applying for jobs? Check out these blog posts... -
Targeted Mutagenesis with EvolvR
TypeBlog Post...mutational abilities of PolI3m. This tag would allow researchers to trace the progeny of a single starting cell...flexibility to address many different types of research questions. Are you ready to start EvolvR-ing your...Perez-Pinera. "The continuously evolving CRISPR barcoding toolbox." Genome biology 19.1 (2018): 143. PubMed... -
Screening for Successful Genome Editing with Digital PCR
TypeBlog Post...the University of Alberta. If you’re like many researchers these days, you are ready to take (if you haven...are often impractical for small projects. Most researchers instead turn to so-called “mismatch nuclease”...knockout of HIV co-receptor CCR5. Nucleic Acids Research 43, 5560–5571 (2015). PubMed PMID: 25964300. PubMed... -
REPLACR Mutagenesis: Replacing In Vitro Recombination Methods
TypeBlog Post...Site-directed mutagenesis (SDM) is one of the key tools researchers use to prove causation in molecular biology and...inactivating/activating mutations. In biomedical research, modeling patient mutations using SDM can help...Perfect Plasmid Backbone Find Plasmids for Your Research ... -
Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur
TypeBlog Post...engineer and scientist, I like to envision that my research will have a direct impact on healthcare and the...result, I have occasionally pondered translating my research into a startup company. However, like many like-minded...incorporated into Novophage Therapeutics, Inc. in March 2009 and tested in the “market” by competing in ... -
Transferable Skills Guide: Cross-team Communication
TypeBlog Post... long tenure at Addgene. I would work with our research team and software engineers to update our Lab ...engineer that you want the LIMS software to create a barcode for your plate, you will get in trouble if you ...given container Whether or not the container was barcoded (this is pretty Addgene specific) The types or... -
Hot Plasmids April 2018 - Protein Degradation, Nanoscopy, FIRE-Cas9, and Yeast Expression Tools
TypeBlog Post... podcast segment CRISPR and RNAi have helped researchers alter DNA sequence and RNA expression - but what... Yeast Transcription Factors Podcast Segment Researchers from the El-Samad lab recently deposited plasmids...that this level of control will enable future researchers to better simulate physiological gene expression...