We narrowed to 259 results for: OVA
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TypeBlog Post...postdoc positions, including AstraZeneca, Pfizer, Novartis, Biogen, Amgen, New England Biolabs, Regeneron...pre-approved project. Other companies, such as Novartis, have specific web sites for postdoc listings,...
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When is a Monomer not a Monomer? The Top Three Ways Your Favorite Fluorescent Protein Oligomerizes in Cells
TypeBlog Post...remain unaware that EGFP/GFP is prone to forming noncovalent dimers. This property of EGFP can lead to significant...EGFP/GFP has a real nontrivial propensity to noncovalently dimerize. That means that your POI fused to ... -
Plant Plasmids and Resources
TypeCollection... exchange, open technologies, and responsible innovation for improvement of sustainable agriculture and... -
Plasmids 101: Secondary Nanobody Toolbox
TypeBlog Post...incubation can be skipped by pre-binding to 1° Monovalent Monoclonal Only anti- rabbit and -mouse versions...Maleimide-labeling occurs when a maleimide group forms a covalent bond with a sulfhydryl group (–SH), such as that... -
An Introduction to Adenovirus
TypeBlog Post...likely for adenoviral vectors – namely due to the removal of certain adenoviral genes that apparently contribute...36996871. Tatsis, N., Fitzgerald, J. C., Reyes-Sandoval, A., Harris-McCoy, K. C., Hensley, S. E., Zhou... -
Getting to Know Expansion Microscopy
TypeBlog Post...have been found to help improve label density (Mikhaylova, et al. 2015). Despite these limitations, ExM.... https://doi.org/10.1038/s41587-022-01546-1 Mikhaylova M, Cloin BMC, Finan K, et al (2015) Resolving... -
Arf GTPase Family
TypeCollection...Link opens in a new window) Sztul, E., Chen, P., Casanova, J. E., Cherfils, J., Dacks, J. B., Lambright,... -
Viral Vectors
TypeCollection...relative to natural viruses) for safety through the removal of certain genes that are required for viral replication... -
What's Your Organism? Expanding Genomic Tools via the NSF EDGE Program
TypeBlog Post...program should “enable the ability to study life’s innovations from anywhere in the tree of life.” Accepted ...manipulation. The ReMOT control system (Receptor-Mediated Ovary Transduction of Cargo) delivers Cas9 RNP to the... -
Designing Your Chalk Talk for the Academic Job Interview
TypeBlog Post...problem and then explain why it’s significant and innovative. For example, "while it is possible to grow liver... best person to do this research? Do you have innovative tools? A novel dataset? Unique expertise? A novel... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog Post...co-founded by Kaspar, acquired by Novartis and rebranded to Novartis Gene Therapies, and Taysha Gene Therapies... -
To Codon Optimize or Not: That is the Question
TypeBlog Post...Optimization References Athey J, Alexaki A, Osipova E, Rostovtsev A, Santana-Quintero LV, Katneni U...Addgene;s dataset reveals trends in biological innovation Resources on Addgene.org Check out Addgene'... -
The PAM Requirement and Expanding CRISPR Beyond SpCas9
TypeBlog Post...Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F (2015) In vivo... B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der... -
Hot Plasmids - August 2020
TypeBlog Post...derived either from p63(1-29) and Lck. Image from Chertkova et al., 2020. In their BioRxiv post, the authors...mammalian cell structure markers plasmids at Addgene! Chertkova, AO, et al., bioRxiv. 2020. https://doi.org/10.1101... -
Viral Vectors 101: Pseudotyping
TypeBlog Post...achieve a high titer (reviewed in Joglekar and Sandoval, 2017). This high titer is one of the reasons ...https://doi.org/10.3390/v12091016 Joglekar AV, Sandoval S (2017) Pseudotyped Lentiviral Vectors: One Vector... -
Control AAV Preps
TypeCollection...produced with the AAV retro helper plasmid from the Karpova and Schaffer labs. See the Retrograde AAV Inventory... -
An Integrin Antibody Toolkit from IPI
TypeBlog Post...inhibited. Recently, we at the Institute for Protein Innovation (IPI), a Boston-based, nonprofit protein research...a science writer at the Institute for Protein Innovation. She writes about all things IPI, from the scientists... -
New Optogenetic Tools for Cytoskeleton and Membrane Control
TypeBlog Post...are not easily reversible. Late last year, the Akhmanova Lab published a new optogenetic tool for localized...Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool ... -
Evolution of Lab Techniques
TypeBlog Post...papers or are brainstorming new technological innovations. Let’s take a look at three historical techniques...past. In the sequencing world, one up and coming innovation is nanopore-based DNA sequencing which reads ... -
Viral Vectors 101: Systemic Capsids
TypeBlog Post...throughout the central nervous system. Nature Cardiovascular Research, 1(4), Article 4. https://doi.org/...Gore, B. B., Weed, N., Omstead, V., Bishaw, Y., Shapovalova, N. V., Martinez, R. A., Fong, O., Yao, S., Mortrud...