...control both when and where genome editing happens. CASANOVA , developed by Dominik Niopek’s lab , is a way...improved kinetics LSD1 - repression through targeted removal of H3K4 and H3K9 methylation In certain cases, ... maintained by the Jennifer Doudna lab at the Innovative Genomics Institute, University of California,... Science , 339 (6121), 823–826. PMID: 23287722 Makarova, K. S., Wolf, Y. I., Alkhnbashi, O. S., Costa,... Kriz, A. J., Zetsche, B., Shalem, O., Wu, X., Makarova, K. S., Koonin, E. V., Sharp, P. A., & Zhang, ...Cian, A., Itier, J. M., Anegon, I., Lopez, B., Giovannangeli, C., & Concordet, J. P. (2018). CtIP fusion ..., Ladha, A., Gardner, Z., Schmid-Burgk, J. L., Makarova, K. S., Koonin, E. V., & Zhang, F. (2019). RNA-guided...

...10.1261/rna.2192803 PMID: 12649500 Timms, R. T., Tchasovnikarova, I. A., & Lehner, P. J. (2018). Differential...activation of viral genomic RNA transcription. Removal of this region in the 3’ LTR in third-generation...

...Lavzin, M., Ritola, K. D., Lindo, S., Michael, S., Kuleshova, E., Ojala, D., Huang, C. C., Gerfen, C. R., Schiller...Hantman, A. W., Looger, L. L., Schaffer, D. V., & Karpova, A. Y. (2016). A designer AAV variant permits efficient...

...activation of viral genomic RNA transcription. Removal of this region in the 3’ LTR creates self-inactivating...

...sdAb. sdAbs can have weak signals due to their monovalent nature. Darpins - Darpins are genetically engineered...