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We narrowed to 167 results for: tox

Showing: 121 - 140 of 167 results

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Light Sheet Fluorescence Microscopy

Type

Blog Post

...order to improve axial resolution and reduce phototoxicity for imaging live specimens, they combined light...
New Optimized Genome-wide CRISPRko, CRISPRi, and CRISPRa Libraries

Type

Blog Post

...the Brunello knock-out library while mitigating toxicity induced by high copy number dsDNA cutting. A Dolcetto...
AAVs CREATed for Gene Delivery to the CNS and PNS

Type

Blog Post

...long-term expression; and 3) they have limited toxicity. However, a key challenge of using AAVs for neuroscience...
CRISPR Antimicrobials

Type

Blog Post

...pair change in DNA gyrase, CRISPR phagemids were cytotoxic only for resistant bacteria. Bikard et al. used...
Fluorescent Proteins 101: Green Fluorescent Protein (GFP)

Type

Blog Post

...fluorescent dyes of the time was the fact that it was non-toxic and could be expressed in living cells, enabling...
Fluorescent Protein Guide: Subcellular Localization

Type

Collection

...B4GALT1(1-61) mTurquoise2 Dorus Gadella 68073 GalToxBFP Golgi apparatus GalT signal anchor transmembrane...
Plasmids 101: Stringent Regulation of Replication

Type

Blog Post

... protein, which can be useful if the product is toxic in high amounts. These plasmids are also useful ...
Fluorescent Proteins 101: Aptamer Fluorophores

Type

Blog Post

...visualization technique. Ultimately, MG proved to be too toxic for many in vivo applications, but this work proved...
Plasmids 101: Gateway Cloning

Type

Blog Post

...containing the ccdB gene. Since the ccdB product is toxic to the cell, Gateway cloning efficiency can reach...
Overcoming the AAV Size Limitation for CRISPR Delivery

Type

Blog Post

...did so without a substantial immune response or toxicity. More AAV-based CRISPR systems Smaller Cas proteins...
Rett Syndrome: A History of Research and Therapeutic Outlooks

Type

Blog Post

...the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery. Molecular Therapy...
5 Reasons to Use Reddit for Science Communication

Type

Blog Post

...career topics. However, many of the posts were about toxic advisors, fruitless job searches, and even despair...
Plasmids 101: The Promoter Region – Let's Go!

Type

Blog Post

...even kill your cells if your gene of interest is toxic. To combat this, scientists have created synthetic...
Viral Vectors 101: Integrase-Deficient Lentiviral Vectors

Type

Blog Post

...Cas9 is no longer necessary. However, Cas9 can be toxic if continuously expressed (Fu et al., 2013). Using...
Hot Plasmids: Summer 2024

Type

Blog Post

...methyltransferase for epigenetic silencing, which can be toxic, CHARM uses a cofactor fused to a histone tail to...
Antibodies 101: Introduction to Gating in Flow Cytometry

Type

Blog Post

...-mouse CD8b-PerCP-Cy5.5), which is present on cytotoxic T killer cells but not dendritic cells. Using ...
Deep Mutational Scanning with One Pot Saturation Mutagenesis

Type

Blog Post

...display assays, ubiquitination activity assays, toxin activity, small molecule binding, growth rate, and...
CRISPR 101: Homology Directed Repair

Type

Blog Post

... can be used, however, these are generally more toxic to cells than their plasmid counterparts. Another...
Four Ways to Package Transgenes That Exceed the Size Limit of Adeno-associated Virus

Type

Blog Post

...non-functional, they could be dominant-negative and/or toxic. A potential solution is to include an in-frame ...
Five Popular Model Organisms

Type

Blog Post

...Yeast models of PD, like those that overexpress the toxic protein α-synuclein (the most common protein found...

Showing: 121 - 140 of 167 results

Results per page:

Light Sheet Fluorescence Microscopy

New Optimized Genome-wide CRISPRko, CRISPRi, and CRISPRa Libraries

AAVs CREATed for Gene Delivery to the CNS and PNS

CRISPR Antimicrobials

Fluorescent Proteins 101: Green Fluorescent Protein (GFP)

Fluorescent Protein Guide: Subcellular Localization

Plasmids 101: Stringent Regulation of Replication

Fluorescent Proteins 101: Aptamer Fluorophores

Plasmids 101: Gateway Cloning

Overcoming the AAV Size Limitation for CRISPR Delivery

Rett Syndrome: A History of Research and Therapeutic Outlooks

5 Reasons to Use Reddit for Science Communication

Plasmids 101: The Promoter Region – Let's Go!

Viral Vectors 101: Integrase-Deficient Lentiviral Vectors

Hot Plasmids: Summer 2024

Antibodies 101: Introduction to Gating in Flow Cytometry

Deep Mutational Scanning with One Pot Saturation Mutagenesis

CRISPR 101: Homology Directed Repair

Four Ways to Package Transgenes That Exceed the Size Limit of Adeno-associated Virus

Five Popular Model Organisms

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