CRISPR Activators: A Comparison Between dCas9-VP64, SAM, SunTag, VPR, and More!
Type
Blog Post
...then recruit additional activation domains (HS1 and p65).
Performance
When targeting single genes, SAM consistently... as two other potent transcriptional activators (p65 and Rta). These transcriptional activators work in...activators, fusing the epitope tag of SunTag with the P65-HSF activation domains used in SAM. This method has...