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  1. p53 Pathway

    Type
    Collection
    ...name to find available plasmids for the gene, or browse the gene list below. For multiple isoforms or subunits...for the gene. For components with multiple isoforms or subunits, individual links to each gene page are...especially important to tumorigenesis. Inheriting only one functional copy of the p53 gene causes a large reduction...content for this page was generated with the help of . Return to top p53 Pathway - Gene List Click on a name... Ras pathway Background p53 Pathway Plasmids p53 Gene List References Background p53 is a transcription...Cancer Impact p53 is the most frequently mutated gene (>50%) in human cancer; most of these mutations ... subunits, individual links to each gene page are provided below. Color is used for clarity and does not...
  2. TALENs for Endogenous Zebrafish Genes

    Type
    Collection
    ...zebrafish genes; many of these were generated as part of an NIH-sponsored effort to provide gene-editing...zebrafish genes. TALengineering... TALengineering Reagents TALEN Zebrafish Reagents TALENs for Endogenous Zebrafish Gene Targets...gene-editing nucleases to the zebrafish community. Target Gene Name TALENs Full Target Site (5' to 3'; half-sites...TCACGGCGAACAACACTAccgatccgttcgggagGAACGAAGATGTGGCCAA bbc3-(puma) TAL3030 & TAL3031 TGGCACGCCGAACAGCTGcaggatggaggtgctgCGTCAGGACGCCTGGCCA...
  3. Viral Vectors 101: Pseudotyping

    Type
    Blog Post
    ...Precious Tools to Improve Gene Modification of Hematopoietic Cells for Research and Gene Therapy. Viruses 12...To deliver genes using lentiviral vectors, you need an envelope protein on the virus’s surface and a ... plasmid which contains a promoter, the envelope gene, and a polyA tail.   Figure 1: Lentiviral...can’t be used for neuronal tracing or peripheral gene delivery. Combining the rabies glycoprotein into...Lentiviral Vectors: One Vector, Many Guises. Human Gene Therapy Methods 28:291–301 . https://doi.org/10.1089...Resources on Addgene.org: Check out the lentivirus guide Find ready-to-use lentiviral preps at Addgene ...your viral vector, you use the same protocol for generating lentivirus, but you use a different envelope ...
Showing: 1 - 3 of 3 results