We narrowed to 70 results for: raly
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TypeBlog Post...high-throughput SARS-CoV-2 pseudovirus neutralization assay. Neutralization was quantified in terms of luminescence...MIT, and Harvard, and his lab found that the neutralization effectiveness of current vaccines differed ... doses of the Moderna or Pfizer vaccine could neutralize many variants, including the B.1.1.7 (Alpha variant....1.351 (Beta variant) were much less effectively neutralized. The B.1.617.2 (Delta variant) was not tested...at the time of this study. Figure 1: Neutralization levels against spike pseudovirus decreases ... on the variant. The lowest levels of cross-neutralization occurs in the P.1 and B.1.351 variants tested...permission. The spike variant pseudovirus neutralization assay Balazs’s lab, which studies immunity ...
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SARS-CoV-2 Pseudotyped Virus
TypeCollection...mechanisms of infection and to determine methods of neutralizing the virus or reducing its infective potential...that can be used for measuring infectivity and neutralizing activity are listed below: pBOBI-FLuc - Lentiviral...Posts Viral Vectors 101: Pseudotyping Antibody Neutralization Response Against Pseudoviruses Expressing SARS-CoV... -
COVID-19 Resources
TypeCollection...used for measuring viral entry and activity in neutralization assays and links to popular envelope and packaging...constructs now available from Andrea Pauli's lab. Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block... -
Rett Syndrome
TypeCollection...mouse line developer and repository, and CRO for centralized behavior scoring (Link opens in a new window)...28544139 Laurvick et al. 2006. Rett syndrome in Australia: a review of the epidemiology. J Pediatric . 148... -
Finding Your Perfect Job After University
TypeBlog Post...Research in Australia I then travelled abroad to work at the University of Queensland in Australia, this was...months in Australia or another country of the Commonwealth. Another reason why I chose Australia was because... -
Improving Transduction Efficiency with Exosome AAVs
TypeBlog Post...also found that exo-AAVs were more resistant to neutralizing anti-AAV antibodies. This is particularly useful...vivo where endogenous anti-AAV antibodies often neutralize the therapeutic efficacy of AAV vectors. How ...Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo.... -
Fluorescent Proteins 101: Luciferases
TypeBlog Post...Commons. The North American firefly, Photinus pyralis, catalyzes a chemical reaction in its abdomen to...Cofactors Secreted North American firefly (Photinus pyralis) Natural or codon-optimized 562 61 Luciferin ATP...Furimazine None Optional AkaLuc(derived from Photinus pyralis) Engineered 677 61 AkaLumine ATP No Common... -
A Look Back at One Year of Plasmid Sharing for COVID-19 Research
TypeBlog Post...later used by another team of researchers for neutralization assays, part of a study that examined the repertoire...effective sera from vaccinated individuals are at neutralizing the different SARS-CoV-2 spike variants. You...Particles with SARS-CoV-2 Spike Protein for Neutralization Assays. Viruses 12:513. https://doi.org/10.3390... -
Enabling Precision Functional Genomics with the Target Accelerator Plasmid Collection
TypeBlog Post...assays, we figured that they would need to be generalizable and capable of measuring a variety of molecular... and morphological profiling can be used as generalizable strategies to map the function of rare cancer... -
Supporting Rare Disease Research with the 2020 BeHEARD Awards
TypeBlog Post...Mark Mellett: IL-36 biology in generalized pustular psoriasis Generalized pustular psoriasis is a chronic... -
Adeno Associated Virus (AAV) for Cell and Gene Therapy
TypeBlog Post...prevent AAV infection. For example, prevalence of neutralizing antibodies against some AAV types, AAV1, 2, ...own immune systems can develop antibodies that neutralize the AAV vectors used to treat them. Scientists... -
Twenty Years of Addgene Sharing: CRISPR
TypeBlog Post...FR=France; KR=South Korea; CH=Switzerland; AU=Australia. It probably comes as no surprise that the...plasmids. But many other countries, from Japan to Australia, are significant depositors and requestors. CRISPR... -
Viral Vectors 101: Systemic Capsids
TypeBlog Post...administered concurrently to minimize the impact of neutralizing antibodies developed in response to the first...with slightly reduced efficiency, and is not neutralized by pre-existing antibodies against AAV9-based... -
2021 Deck the Lab Winners!
TypeBlog Post...Yit Heng Chooi Lab at the University of Western Australia. 🤩 our lab in Bayliss Building @SMS_UWA is... -
Export Control Regulations Lifted for Plasmids Containing Rabies and VSV-G Genes
TypeBlog Post... the international controls prescribed by the Australia Group, for these plasmids for the majority of ... -
The Developmental Studies Hybridoma Bank: Over 25 Years of Antibody Sharing
TypeBlog Post...such as bacteria or viruses, which results in neutralization or targeted destruction. Antibodies are composed... -
A Scientist's Guide to Ebola
TypeBlog Post...critical component of vaccines and the target of neutralizing antibodies and inhibitors of attachment and ... -
Interview with Bart Newland, Addgene’s Newest Board Member
TypeBlog Post...about risks and how to manage them without them paralyzing an organization. I think these are things that... -
Six Spooky Science Stories and Halloween at Addgene
TypeBlog Post...spooky science stories Zombie ants Ophiocordyceps unilateralis is a fungus that infects ants and controls their... -
Scientific Sharing in the Time of COVID-19: Databases and Resources
TypeBlog Post...world. To support this pace of research, new, centralized databases and centers to support the sharing ...