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Showing: 181 - 200 of 545 results

  2. Reagent Repositories Are Speeding up Science During the Pandemic

    Type
    Blog Post
    Published
    Aug. 4, 2020, 1:15 p.m.
    ...they provide rapid access to validated reagents, especially during a time when these materials may not be...of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus. JVI 81:813–821 . https:...

  4. Using CRISPR/Cas9 to Edit Disease Out of the Genome

    Type
    Blog Post
    Published
    June 23, 2022, 1:15 p.m.
    ...using CRISPR/Cas9. They are targeting the genes responsible for both early onset and late onset AD. In this...ability to influence editing efficiency. In 2022, despite the increasing effectiveness of CRISPR/Cas9, scientists...

  5. New Neuroscience Tool: The iGluSnFR3 Glutamate Sensor

    Type
    Blog Post
    Published
    April 7, 2022, 1:15 p.m.
    ...by glutamate, and tweaking it to improve its responsiveness, they showed that iGluSnFR could detect neuronal...sensitive and better localized for synaptic glutamate response than its predecessors. The detailed characterization...

  7. Multiplexed Overexpression of Regulatory Factors (MORF) collection

    Type
    Blog Post
    Published
    March 30, 2023, 1:15 p.m.
    ...classify unknown, or ‘orphan’, TFs into their respective families. Given the number of poorly studied ...cellular fates were then matched with candidate TFs responsible for that differentiation.   Fig. 2: Single...

  8. What Good Citizenship Can Do for Reproducibility in Science

    Type
    Blog Post
    Published
    Nov. 7, 2019, 2:18 p.m.
    ... can and do play this role, and we take our responsibility to push for clear communication of science ...broader role as Vice President. Her current responsibilities encompass overall leadership of the Cell Press...

  9. Components of CRISPR/Cas9

    Type
    Blog Post
    Published
    Feb. 2, 2016, 5 p.m.
    ...is a variant with increased PAM flexibiliy and eSpCas9/SpCas9-HF1 have increased targeting specificity...CRISPR/Cas systems have a variety of enzymes responsible for processing foreign DNA as well as the RNA...

  11. Plasmids 101: Mammalian Vectors

    Type
    Blog Post
    Published
    March 25, 2014, 3:15 p.m.
    ...rate than that of bacteria (~24 h vs 20 min, respectively). Therefore, it is not always mission critical...plasmids containing the viral EBV or SV40 ORIs, respectively. The presence of these viral components greatly...

  13. Early Career Researcher Toolbox: Social Media for Scientists

    Type
    Blog Post
    Published
    Dec. 11, 2018, 12:46 p.m.
    ...and others have used Twitter professionally. I especially love Dan’s advice to tap into the online conversations... tips for getting the most out of the site. I especially like the pointers on how to use LinkedIn to research...

  14. Sweating the Small Stuff: Details in the Lab

    Type
    Blog Post
    Published
    Feb. 8, 2022, 2:15 p.m.
    ...made a huge difference in my ability to focus, especially on days when I was tired, stressed, or rushing...Try a variety of things, including (and maybe especially) suggestions you are initially resistant to. ...

  15. Plasmids 101: Screens vs. Selections

    Type
    Blog Post
    Published
    Nov. 10, 2022, 2:15 p.m.
    ... a patient mutation to assess how patients may respond to drug treatment. Another example is using a mouse...gene expression temporarily. RNAi libraries are especially useful if you are interested in studying genes...

  17. How to Make Friends and Meet People at a Scientific Conference

    Type
    Blog Post
    Published
    Aug. 7, 2014, 1:58 p.m.
    ...ready to talk about them. People love to help especially when solving problems.  During the conference...input. Connect with people you met on LinkedIn, especially if they are not in academia. Make sure to learn...

  18. Dos & Don'ts When Publishing a Scientific Manuscript

    Type
    Blog Post
    Published
    May 22, 2014, 4:02 p.m.
    ... their decision. If you do object, do so in a respectful and professional manner. Arguing will make you...is a Developmental Editor for F1000Research, responsible for assessing the scientific content of manuscripts...

  19. Form Your Own Peer Mentoring Group: A How-To Guide for Scientists

    Type
    Blog Post
    Published
    Feb. 18, 2014, 4:22 p.m.
    ...Senior people (of which there are never enough, especially in underrepresented groups) reach multiple mentees...in a rotation. The leader for that meeting is responsible for choosing a topic and leading the discussion...

  20. Will You Be My Mentor? Finding and Asking for Mentoring Support

    Type
    Blog Post
    Published
    Feb. 4, 2014, 3:50 p.m.
    ... to be your mentor, it may sound like a big responsibility or commitment. Start by asking them to have...questions and topics to discuss. The mentee is responsible for leading the discussion and for being “coachable...
Showing: 181 - 200 of 545 results