We narrowed to 554 results for: ESP
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TypeBlog PostPublishedNov. 27, 2018, 2 p.m....that can sense contaminants and emit light as a response. To create this bacterial sensor, he will construct... activate fluorescent protein transcription in response to river contaminants and transform these plasmids...
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Creating accessible biology activities in schools with BioBits
TypeBlog PostPublishedAug. 2, 2018, 12:56 p.m....equivalent of a “chemistry kit” for topics in biology, especially those at the molecular and cellular level. The... of this is conducive to a classroom setting, especially for a school with a limited budget. While there... -
What Good Citizenship Can Do for Reproducibility in Science
TypeBlog PostPublishedNov. 7, 2019, 2:18 p.m.... can and do play this role, and we take our responsibility to push for clear communication of science ...broader role as Vice President. Her current responsibilities encompass overall leadership of the Cell Press... -
New and Upcoming Viral Vectors - September 2019
TypeBlog PostPublishedSept. 12, 2019, 1 p.m....specific parameters: jGCaMP7s is the most sensitive responder to action potentials. For a single action potential...brighter than GCaMP6s. jGCaMP7f is the fastest responding variant. jGCaMP7b exhibits the brightest resting... -
Multiplexed Overexpression of Regulatory Factors (MORF) collection
TypeBlog PostPublishedMarch 30, 2023, 1:15 p.m....classify unknown, or ‘orphan’, TFs into their respective families. Given the number of poorly studied ...cellular fates were then matched with candidate TFs responsible for that differentiation. Fig. 2: Single... -
Using CRISPR/Cas9 to Edit Disease Out of the Genome
TypeBlog PostPublishedJune 23, 2022, 1:15 p.m....using CRISPR/Cas9. They are targeting the genes responsible for both early onset and late onset AD. In this...ability to influence editing efficiency. In 2022, despite the increasing effectiveness of CRISPR/Cas9, scientists... -
New Neuroscience Tool: The iGluSnFR3 Glutamate Sensor
TypeBlog PostPublishedApril 7, 2022, 1:15 p.m....by glutamate, and tweaking it to improve its responsiveness, they showed that iGluSnFR could detect neuronal...sensitive and better localized for synaptic glutamate response than its predecessors. The detailed characterization... -
Crowdfight, a Platform to Boost Scientific Collaboration During COVID-19 and Beyond
TypeBlog PostPublishedJune 1, 2021, 1:15 p.m.... illustrates the power of collaboration, which despite the competitiveness of cutting-edge research, is... list. We then collected and classified their responses, and used that information to deliver to the requesters... -
Reagent Repositories Are Speeding up Science During the Pandemic
TypeBlog PostPublishedAug. 4, 2020, 1:15 p.m....they provide rapid access to validated reagents, especially during a time when these materials may not be...of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus. JVI 81:813–821 . https:... -
Quantifying DNA? Here are Five DNA Quantification Methods to Consider
TypeBlog PostPublishedJuly 21, 2020, 1:15 p.m....methods are more sensitive than UV absorbance, especially when you expect low concentrations in your samples...samples with a known DNA quantity and their corresponding fluorescence. That way, you can compare the ... -
Components of CRISPR/Cas9
TypeBlog PostPublishedFeb. 2, 2016, 5 p.m....is a variant with increased PAM flexibiliy and eSpCas9/SpCas9-HF1 have increased targeting specificity...CRISPR/Cas systems have a variety of enzymes responsible for processing foreign DNA as well as the RNA... -
Plasmids 101: How to Verify Your Plasmid Using a Restriction Digest Analysis
TypeBlog PostPublishedAug. 28, 2014, 3:34 p.m....matching the backbone and insert, respectively. The results on the gel correspond to the predicted sizes. Watch... -
Plasmids 101: Mammalian Vectors
TypeBlog PostPublishedMarch 25, 2014, 3:15 p.m....rate than that of bacteria (~24 h vs 20 min, respectively). Therefore, it is not always mission critical...plasmids containing the viral EBV or SV40 ORIs, respectively. The presence of these viral components greatly... -
Early Career Researcher Toolbox: Social Media for Scientists
TypeBlog PostPublishedDec. 11, 2018, 12:46 p.m....and others have used Twitter professionally. I especially love Dan’s advice to tap into the online conversations... tips for getting the most out of the site. I especially like the pointers on how to use LinkedIn to research... -
Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies
TypeBlog PostPublishedJuly 28, 2017, 1:30 p.m....can be dissected at various times throughout the lifespan of the fly to determine the implications of your...differentiation (a cell type important for adaptive immune responses, which flies do not have!) (4). The power of Drosophila... -
A Quick Guide to a Career in Software Product Management
TypeBlog PostPublishedNov. 24, 2020, 2:15 p.m..... 4:00 PM--Respond to customer help tickets. Catch up on customer help tickets, and respond when I have... -
Plasmids 101: Screens vs. Selections
TypeBlog PostPublishedNov. 10, 2022, 2:15 p.m.... a patient mutation to assess how patients may respond to drug treatment. Another example is using a mouse...gene expression temporarily. RNAi libraries are especially useful if you are interested in studying genes... -
Sweating the Small Stuff: Details in the Lab
TypeBlog PostPublishedFeb. 8, 2022, 2:15 p.m....made a huge difference in my ability to focus, especially on days when I was tired, stressed, or rushing...Try a variety of things, including (and maybe especially) suggestions you are initially resistant to. ... -
How to Make Friends and Meet People at a Scientific Conference
TypeBlog PostPublishedAug. 7, 2014, 1:58 p.m....ready to talk about them. People love to help especially when solving problems. During the conference...input. Connect with people you met on LinkedIn, especially if they are not in academia. Make sure to learn... -
Dos & Don'ts When Publishing a Scientific Manuscript
TypeBlog PostPublishedMay 22, 2014, 4:02 p.m.... their decision. If you do object, do so in a respectful and professional manner. Arguing will make you...is a Developmental Editor for F1000Research, responsible for assessing the scientific content of manuscripts...