We narrowed to 559 results for: ESP

... on which lab jobs needed to be done (Who is responsible for making the running buffer this week?). Scientists...what is most important to each person. It can especially be difficult to think creatively when you are...create a win-win situation? Learning about and respecting cultural differences is a crucial part of understanding...

...expensive to gain access to routinely, and it can be especially challenging when trying to develop antibodies... a defined set of different trinucleotides (corresponding to different amino acids) in the regions that...further characterization and analysis. In a rapid response to the COVID-19 pandemic, the Seeger lab demonstrated...

...there’s a PAM near your insertion site, the corresponding gRNA might be undesirable due to potential off-target...than SpCas9, in this case, NNGRRT and NNNNGATT, respectively. Researchers also engineered SpCas9 variants..., resulting in lower overall genome frequency. Despite the progress we’ve made, there is still a need ...

...with the Krauthammer lab (University of Zurich), especially with my deep learning-wizard colleague Ahmed ...selecting the most promising pegRNA designs and especially facilitates the use of prime editing in pooled...true for any prime editor experimentalist, and especially shines once large-scale prime editing experiments...

...fluorescent proteins, it’s important to note that despite their distinction by name, chromoproteins are actually...pTOX6 express the YhaV, MqsR, and Tse2 toxins, respectively, and all encode the amilCP chromoprotein. Vectors...pTOX9 express the YhaV, MqsR, and Tse2 toxins, respectively, and encode the tsPurple chromoprotein.  Find...

...without triggering a destructive inflammatory immune response. At the time, adenoviral vectors were the most...disease-causing genes, including the RPE65 gene responsible for an autosomal recessive, severe, childhood-onset...follow in the footsteps of Luxturna™. However, despite promising results in preclinical studies some potential...

...are also an important target for gene delivery, especially for the study of pain. While many new capsids...and AAV.PHP.S, that target the CNS or the PNS, respectively.  Read on to learn more about these two new ...Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature biotechnology...

...individual molecules. Poor photon budgets are a widespread issue with fluorescent proteins—even the thriftiest...student searching couch cushions for spare change, desperate to extract a few more photons from a sample. Chemical...have excellent properties inside living cells, especially for advanced imaging experiments. We continue...

...and it would have been very difficult for us to respond to such a large number of requests by ourselves...with each other, which is critically important, especially for young researchers. It was a really nice incubator...Identification of Proteins Associated with an IFNgamma-Responsive Promoter by a Retroviral Expression System for...

... Wilson Lab also looked for the gene variant responsible for the PHP.B permissive phenotype in mice. They...transfer to the rat CNS: AAV PHP. EB vector dose–response and comparison to AAV PHP. B." Gene therapy 25.5...Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain." Nature biotechnology...