We narrowed to 740 results for: NSI

...technique! What is a photosensitizer? First, for a few definitions. A photosensitizer is a dye or protein...system? Turns out that with light-inducible photosensitizers and a quick zap of the proper color light,...light, you can do just that.  Photosensitizing dyes and proteins have been around for awhile (check out this...Bruchez and Tsang labs recently developed a photosensitizer composed of the protein complex complex and... oxygen species (ROS). The ROS produced by photosensitizers inactivate target proteins or cells while ...having little effect on neighboring cells. The photosensitizer used in this work is composed of two parts:...fluorogen (the TAP - targeted and activated photosensitizer - MG-2I in this case). The fluorogen is not...

... as channelrhodopsins (ChRs) makes them light-responsive. When light shines on excitatory channelrhodopsin-expressing...tissue culture dish but can also happen in real-time inside a mouse’s brain.  But the brain is a tricky organ...mm3). Current channelrhodopsins also need high-intensity light for activation which requires implantation...design new channelrhodopsins that are more light sensitive and have enhanced conductance compared to current...channelrhodopsin’s photocurrent strength, wavelength sensitivity, and off-kinetics.   This model was then used... measured photocurrent amplitude, wavelength sensitivity, and off-kinetics correlated with the model’s... produced stronger photocurrents at low light intensity than existing channelrhodopsins CoChR and/or ChR2...

...Understanding the transition While a PhD equips you with exceptional technical skills, transitioning into management...   Strategies for a successful transition To successfully transition into a managerial role, it's essential...mentors who have made similar transitions can provide you with insights, lessons from their experiences... most pivotal decisions many PhDs face when transitioning from academia to industry is whether to stay...preparation and a willingness to embrace new responsibilities. After my second postdoc, I realized that...career trajectories within the industry, but the transition wasn’t easy - I had to reinvent myself and redefine...d like to share below. Common pitfalls in the transition (what I wish I knew before experimenting on myself...

...to individual researchers. Yet accurate and comprehensible organization of data is essential for efficient...store raw data in formats that require specific (expensive) software that evolves over time such that prior... the journals themselves should be primarily responsible for storage.  If datasets are too large to transfer...projection of it, could allow idea generation and extension, based on existing, published data. The importance...However, expectations must also be reasonable, sensitive to the data type and made as facile for both the...

...and quantify based on band intensities of your DNA relative to the intensity in the ladder. It’s best to...things to consider: cost, time, equipment, and expected DNA concentration. It’s important to consider the advantages...any special reagents. However, there’s limited sensitivity at low concentrations of DNA and it can’t distinguish...measure all nucleic acids). These methods are more sensitive than UV absorbance, especially when you expect... to compare the band intensity of the fragment in the ladder that is closest in size to your piece of ...nm. This method is time consuming and has low sensitivity so it’s not used much. However, the measurements...

...and a Spanish minor, it’s time for me to start considering my future path. Talking to Addgenies has helped...biggest takeaways from my co-op. It has been so insightful to learn about different career paths, successes...

...researchers, we wondered how we could make the insights gained during this time more visible and thereby... ReFigure saves time, knowledge and makes your insights discoverable. Watch this quick video to learn ... ground again and again as they don’t save the insights they glean from a reading session. To remember...notes on a “Pinterest for scientists”? ReFigure extension is a simple Chrome plugin that allows you to save...papers to find the right experiment! The ReFigure extension also tells readers if a paper they’re reading ...ReFigure making it easy for others to discover your insights on a topic. Beyond collating other’s data, you...instantly and are editable by the author at any time. Insights contained in your ReFigure could be beneficial...

...networks, and specific neuronal populations to consider. To tease apart how different neurons impact a...experimental approach you choose, it’s essential to consider the technical limitations of each approach and...

...conducted in Professor Cepko's lab and to get some insight into her management and mentoring styles. If you'd...