Viral Vectors 101: The Retroviral Lifecycle
Type
Blog Post
Published
July 27, 2023, 1:15 p.m.
...that have been developed into retroviral vectors and 2.) a subclass of retroviruses called the lentiviruses...effectively.
Retroviral structure
Figure 2: Structure of a retrovirus. Image re-used from Dong...Dong & Kantor, 2021 under CC-BY license.
Figure 2 gives a detailed view of the structure of a retroviral...transfer of RT, which would actually occur in step 2 during uncoating.
After uncoating, reverse transcription...one of the two strands’ DNA counterparts from step 2 will be integrated by the viral integrase protein ... Air. Environmental Science & Technology Letters, 2(4), 84. https://doi.org/10.1021/ACS.ESTLETT.5B00050...2836(73)90277-5. PubMed PMID: 4355596
King, S. R., Duggal, N. K., Ndongmo, C. B., Pacut, C., & Telesnitsky...