We narrowed to 30 results for: pSC

1. Using CRISPR/Cas9 to Edit Disease Out of the Genome

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   Blog Post

   Published

   June 23, 2022, 1:15 p.m.

   ...basal forebrain cholinergic neurons derived from iPSCs. From Rohn et al. 2018; see figure 3 for full details...

2. Human Germline Editing Using CRISPR

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   Blog Post

   Published

   Aug. 10, 2017, 2:19 p.m.

   ...They observed higher targeting efficiency than in iPSCs, but with the caveat of mosaicism. To circumvent...

3. Lighting Up Cell Signaling with Photoswitchable Kinases

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   Blog Post

   Published

   July 25, 2017, 1:20 p.m.

   ...other photoswitchable kinases: psMEK2, psRaf1, and psCDK5. MEK2 is a serine/threonine kinase with a similar...

4. Fluorescent Proteins 101: Fluorescent Protein Timers

   Type

   Blog Post

   Published

   May 4, 2017, 2:30 p.m.

   ...lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like...

5. Isolating Genomic Regions of Interest with the CRISPR System

   Type

   Blog Post

   Published

   May 30, 2019, 12:44 p.m.

   ... of many human malignancies. Additionally, the Tapscott Lab identified regulators of DUX4, a transcriptional...

6. Adeno-associated Viruses (AAVs) for Genome Editing

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   Blog Post

   Published

   March 27, 2018, 1:32 p.m.

   ...of AAV mediated genome editing in human ESCs and iPSCs from ~0.2% to ~1.5%. In more recent work, researchers...

7. CRISPR 101: Epigenetics and Editing the Epigenome

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   Blog Post

   Published

   June 24, 2020, 5:45 p.m.

   ...certain processes, like cellular reprogramming of iPSCs, more efficient. In general, epigenetic chromatin...

8. PiggyBac-ing Through the Genome Editing Field

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   Blog Post

   Published

   May 31, 2016, 3:30 p.m.

   ...in Lung Epithelial Cells Generated from Patient iPSCs.,” Cell Rep., vol. 12, no. 9, pp. 1385–90, Aug. ...

9. Plasmids 101: Using Transposons in the Lab

   Type

   Blog Post

   Published

   July 6, 2021, 1:28 p.m.

   ...to viral vector delivery of transgenes, like for iPSC reprogramming and gene and cell therapy, and have...

10. 28 Hot Plasmid Technologies from 2015

    Type

    Blog Post

    Published

    Dec. 23, 2015, 3:30 p.m.

    ...capable of promoting induced-pluripotent stem cells (iPSCs) to take on a “neuron-like” phenotype when targeting...