...acknowledge that negative data is something every researcher experiences and that it often provides incredibly...and the CLOVER Center, each one submitted by researchers like you. Reports are reviewed by Addgene scientists...regions and cell types. Power in numbers A Pubmed search for “AAV” and “brain” over the past decade gives...., McGuire, A. L., & Lázaro-Muñoz, G. (2020). Researcher Perspectives on Data Sharing in Deep Brain Stimulation...Data Freedom: The Expansion of Data Sharing in Research Publications...

...want to highlight it for use in your research. Martínez-García et al., BMC Microbiology 2011 Feb 22...progression. One of the major challenges in signaling research is the inability to replicate the spatio-temporal... post-translational modifications in cells and research into its many roles in protein function and signaling...at Yale University previously changed the way researchers can explore important questions surrounding serine...Nicola Patron's MoClo kit and her plant synbio research, read the Addgene interview. Engineering TALENs...order to extend the utility of the system, the researchers developed three new versions. Flipbow employs...

...types in the sample. The visualization helps the researcher see which of the multiplexed sgRNA was involved...browser’s Control+F or Command+F functionality to search for a particular sequence or name. You can perform...educating and supporting novice to expert-level researchers in achieving consistently successful CRISPR experiments...enthusiast, and when she is not guiding CRISPR researchers, she's either day-dreaming about exploring sci-fi...our CRISPR guide Find CRISPR plasmids for your research Find other CRISPR software resources ...

...selection. In a subcutaneous cancer model, the researchers showed that after 24 hours, the unstabilized ...in nature, these systems have been adapted by researchers for many uses when plasmid retention without ...for long-term experiments. They’ve also helped researchers design and optimize cloning methodologies using...genetic modification of Pichia pastoris." FEMS yeast research 9.4 (2009): 600-609. PubMed PMID: 19416369. Kulakauskas....org Check out our molecular biology reference Search for a plasmid here Find plasmids from our special...

...from Ludwig-Maximilians-University in Munich and Marc Tessier-Lavigne’s lab at the Rockefeller University...clones! We would therefore strongly encourage any researcher to incorporate CRISPR/Cas-blocking mutations ...Neurobiology at the Institute for Stroke and Dementia Research, Ludwig-Maximilians-University Munich. His lab... the described project while he was a Postdoc in Marc Tessier-Lavigne’s lab at the Rockefeller University...University in NYC.   Dylan Kwart is a graduate student Marc Tessier-Lavigne’s lab at the Rockefeller University...

... contributed by Jacob Lazarus, a postdoctoral researcher at Harvard. There’s an astounding number of ways... flexneri, Enterobacter cloacae, and Serratia marcescens and have created dozens of deletions as well ...attending physician. He performs post-doctoral research in the lab of Matthew Waldor at Harvard. Now that...sliding at upstream standby sites." Nucleic acids research42.4 (2013): 2646-2659. PubMed PMID: 24234441. PubMed... unmodified Enterobacteriaceae." Nucleic acids research 43.13 (2015): e83-e83. PubMed PMID: 25800749. ...

... lab website, publication records, LinkedIn, ResearchGate or Twitter. Be ready for the interview with ...with the rise of movements such as the Future of Research Symposium and #MeTooSTEM, academic bullies are...first place. This is another reason to do your research and choose wisely. From the Tenure She Wrote blog...undermining personal integrity, destructive innuendo and sarcasm, persistent teasing, name calling, insults, intimidation... to consider less expensive, portable areas of research (transgenic mice—out, zebra fish—in) Team attitude...

...expression or silencing. To alter DNA modifications, researchers used blunt tools like histone deacetylases, but...epigenetic modifications at a user-specified locus. Researchers showed that TALE-TET1 constructs, which fused...transcription at CpG regions of various promoters. Other researchers additionally fused a TAL effector to LSD1 histone...and dCas9-based epigenome editing. Nucleic Acids Research 47:e23–e23. https://doi.org/10.1093/nar/gky1286...system for targeted DNA methylation. Nucleic Acids Research 44:5615–5628 . https://doi.org/10.1093/nar/gkw159...

...the complexity of the system, researchers have used split GAL4 architecture or combined the system with ... ON state, and how you might use these in your research. Today, we’ll look at repressible promoters, which...bind the promoter and repress pADH1 activity. Researchers have engineered pADH1 variants that are less ...(2006). https://doi.org/10.1186/1472-6750-6-43Kaczmarczyk A, Vorholt JA, Francez-Charlot A. Cumate-inducible...

...developed by the GENIE Project team at HHMI's Janelia Research Campus (Aggarwal et al., 2025).In this latest ...genetic cargo of choice. After hearing about researchers' favorite features and limitations of existing...and striatal interneurons (Furlanis, Dai, Leyva Garcia et al., 2025).More than a dozen of these enhancer-AAV...cell morphology. Adapted from Furlanis, Dai, Leyva Garcia et al. 2024 bioRxiv, under a CC-BY-NC-ND 4.0 International...from the article! Furlanis, E., Dai, M., Leyva Garcia, B., Tran, T., … Dimidschstein, J., Fishell, G....