...in contrast, engages existing gene regulatory mechanisms to block activity and does not work easily in...Generating zebrafish transgenics Creating transgenic organisms by introducing foreign DNA into the genome is ...

...and stably maintain the genes they carry among organisms belonging to many different phylogenetic groups...bacteria and express proteins within different host organisms. pBBR1-based plasmids and plasmids in incompatibility...

...many have mechanisms in place to prevent the burden from getting overwhelming. These mechanisms include ...

...have different levels of cytotoxicity and the mechanisms behind the cytotoxicity can vary. For example...differentially inactivated by nonspecific complement mechanisms in serum. Sometimes this is due to the cells ...

...on the escape mechanism of genome editing in microorganisms which could be applied to optimization of genome...cells to understand the genetic and biochemical mechanisms behind their distinct phenotypes and to design...

...versatile tool for precise gene editing in many organisms and model systems. We have used CRISPR/Cas9 extensively...He currently works to understand pathological mechanisms of Alzheimer’s disease by developing novel iPSC-based...

...amongst a subset of methanogenic archea: these organisms lacked a classic cysteinyl tRNA synthetase, despite... Lajoie, Marc J., et al. "Genomically recoded organisms expand biological functions." Science 342.6156...

...developed for tracking various cell types and organisms and for improving the level of detail possible...systems allow single cell dynamics in a variety of organisms to be observed in more detail than ever before...

...an essential coenzyme that is required by all organisms for life. Biotin is only synthesized by plants...post-translational protein modification. Most organisms have less than five enzymes in the entire proteome...

...expression. (a) Several engineered capsids with unique tropisms are now available. These include variants with...specific application and animal model.  Other model organisms Tropism and efficacy can vary depending on species..., 2023 * indicates viral preps available. Mechanisms of crossing the BBB are indicated in parentheses...

...known is that different serotypes have different tropisms but, as you can see, AAVs of each serotype can...Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport...

...genomes. A) Components of the INTEGRATE system. B) Mechanisms of RNA-guided transposition with INTEGRATE. The... Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac...

...and even include profiling single nucleotide polymorphisms (SNPs) (5,12,13). For example, in the Ligase...for characterization of resistance-mediating polymorphisms in African samples of Plasmodium falciparum....

... mitochondrial homeostasis maintained through mechanisms like fission, fusion, biogenesis, and mitophagy...significantly enhanced our understanding of cellular mechanisms. Advancements in dye chemistry have led to the...

... using a viral approach Genetically modified organisms like transgenic mice are important tools for understanding...specific to interneurons in mice as well as other organisms, opening the possibility of using these tools ...

... Australia.    🤩 our lab in Bayliss Building @SMS_UWA is getting festive 🎄🎁🎅🤶🎄 pic.twitter.com/rDaEjxTNZX...

...good light!    🤩 our lab in Bayliss Building @SMS_UWA is getting festive 🎄🎁🎅🤶🎄 pic.twitter.com/rDaEjxTNZX...

...collection is highly diverse in terms of target organisms (from bacteria to mammals), cloning techniques...

...work has focused on elucidating the molecular mechanisms behind interactions between crops like potatoes...

...them in the cell. This blog post features two mechanisms that cause plasmids to be incompatible. 4. RNA...