We narrowed to 24 results for: sms
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TypeCollection...Dee N, Reding M, Ronellenfitch K, Mufti S, Sunkin SM, Smith KA, Esposito L, Waters J, Thyagarajan B, Yao...K, Way SW, Esposito L, Yao Z, Gradinaru V, Sunkin SM, Lein E, Levi BP, Ting JT, Zeng H, Tasic B. Enhancer...Ko AL, Ojemann JG, Keene CD, Silbergeld DL, Sunkin SM, Gradinaru V, Horwitz GD, Zeng H, Tasic B, Lein ES...
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AAVED
TypeCollection... K, Cepko C, Guerin KI, Rego MA, Ersing I, Bachle SM, Kamens J, Fan M. Front Neuroanat. 2019 Nov 26;13... -
Allen Institute for Cell Science Plasmid Collection
TypeCollection...Ludmann SA, Mueller IA, Yang R, Horwitz R, Rafelski SM, Gunawardane RN. Mol Biol Cell. 2017 Oct 15;28(21... -
CRISPR Guide
TypeCollection...knock out target genes in various cell types and organisms, but modifications to various Cas enzymes have... In this section, we will introduce the basic mechanisms of CRISPR and some of the ways the CRISPR components...efficiency, or flexibility of the Cas enzyme. Basic Mechanisms of CRISPR The requirements for a CRISPR knockout...Examples of increased fidelity enzymes, and their mechanisms, include: eSpCas9(1.1) - weaken interactions ...family members inhibit CRISPR by a variety of mechanisms, including blocking crRNA loading or PAM recognition...different locations, by combining other gene editing mechanisms, including transposons, integrases, and recombinases...be added to detect the presence of infectious organisms (like SARS-CoV-2 ) and genetic mutations. Similar... -
Microbiology Resources
TypeCollection...these model organisms. See below for plasmid kits and other resources relevant to these organisms, or use ...depositors are making this possible in a range of organisms. Find CRISPR tools for use in genome editing of... -
CRISPR References and Information
TypeCollection...Supports a range of Cas enzymes (Cas9 and Cas12) and organisms. Developed by the Jin-Soo Kim Lab . Cas-Designer...target site common to a set of similar sequences. Organisms include human, mouse, rat, chicken, frog, zebrafish...upload. Currently supports a wide selection of organisms. From the Database Center for Life Science (DBCLS... -
Mammalian RNAi Tools
TypeCollection.... W., & Sontheimer, E. J. (2009). Origins and mechanisms of miRNAs and siRNAs . Cell, 136 (4), 642–655...Abadi, S. J., & Gharagouzlo, E. (2017). Molecular mechanisms and biological functions of siRNA . International... -
SARS-CoV-2 Pseudotyped Virus
TypeCollection...Viral Pseudotyping SARS-CoV-2 Pseudotyped Virus Mechanisms of SARS-CoV-2 infection remain poorly understood...This approach allows researchers to safely study mechanisms of infection and to determine methods of neutralizing... -
p53 Pathway
TypeCollection...characterized as gain-of-function, expanding the mechanisms by which mutant p53 is known to function in cancer...Thrombospondin 1 Return to top References Unravelling mechanisms of p53-mediated tumour suppression. Bieging KT... -
CRISPR History and Development for Genome Engineering
TypeCollection... aeruginosa . Anti-CRISPR genes employ varied mechanisms to block CRISPR. Some prevent the CRISPR-Cas ...Wiedenheft B, Maxwell KL, Davidson AR. 2015. Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins... -
Fluorescent Protein Guide: Biosensors
TypeCollection...biosensors can be introduced into cells, tissues, or organisms for long-term imaging and can be designed to specifically...calcium sensors (fRCaMP1/2, GECO1/2) The kinetic mechanisms of fast-decay red-fluorescent genetically encoded... -
CRISPR Plasmids - Activate Gene Expression
TypeCollection...upregulating gene expression in various model organisms.... -
CRISPR Plasmids - Cascade-Cas3
TypeCollection...can be repaired by the cell’s endogenous repair mechanisms. Cas3 belongs to the Class 1 family of CRISPR... -
CRISPR Plasmids and Resources
TypeCollection...collections feature plasmids for a variety of organisms, including mammals, plants, bacteria, yeast, Drosophila... -
Malate Dehydrogenase CUREs Community Collection
TypeCollection...expression, structure and function, kinetics and mechanisms of action, regulation and post-translational ... -
Adenovirus Plasmids
TypeCollection...adenovirus plasmids in either mammalian cells or microorganisms, including bacteria and yeast. Two plasmids... -
Zebrafish Plasmid Collection
TypeCollection...screening fluorescent protein fusion expression in organisms or cells in which an exogenous mRNA can be injected... -
TALEN Plasmids and Kits
TypeCollection...Golden Gate cloning method. Validated in multiple organisms. Dan Voytas Adam Bogdanove Joung Lab TAL Effector... -
Neurodegeneration Research Collection
TypeCollection... within 3-5 years from symptom onset. Disease mechanisms are still poorly understood but several genes... -
Rett Syndrome
TypeCollection...differentiated cells that can be used to understand the mechanisms of the disease and for the development of successful...