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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 837 results for: Eras

Showing: 471 - 480 of 837 results

  1. Top 10 Open Science Developments of 2013

    Type
    Blog Post
    Published
    Dec. 19, 2013, 3:46 p.m.
    ...s how science progresses after all, with each generation of scientists standing on the shoulders of their...Technology Policy issued a memorandum calling on Federal agencies with over $100 million in annual R&D expenditures...support increased public access to the results of federally-funded research. 2)      In June, the White House...Bohannon published an article describing a sting operation in which he submitted a phony paper to a list ...

  2. IDP and your PI: A Roadmap for Career Planning and Personal Development

    Type
    Blog Post
    Published
    July 21, 2015, 2:30 p.m.
    ...then formulate a plan to further develop your transferable skills and reach your career goals.      Although...subject matter discussed at the meeting, but the overall tone of the meeting is almost more important. As...Wunderlich Z, Estrada J, Park J, Bragdon MD, Lopez Rivera F, Biette KM, DePace AH. Mol Cell. 2015 Jun 4;58... What Makes a Good Manager Anyway Developing Transferable Skills During Science Training ...

  3. Inside Addgene's 10 Year Anniversary Gala

    Type
    Blog Post
    Published
    July 3, 2014, 3:48 p.m.
    ... the interactive photo graffiti wall. I had a lot of fun playing the prototype of an interactive game ...about her grandfather’s humble beginnings as an operator of a printing press. Just as her grandfather used...the newspaper, Addgene uses E. coli bacteria to generate copies of plasmids. The community of scientists...

  4. Scientific Sharing in the Time of COVID-19: Databases and Resources

    Type
    Blog Post
    Published
    May 12, 2020, 1:15 p.m.
    ...opportunities, protocols, publications, and more to accelerate the pace of research into COVID-19. While this...opportunities, and community response initiatives. Accelerate the translational impact of research Universities...important for creating research synergies and accelerating the translational impact of research activities...Alliance at the CCRP2. Other groups have focused on iterating on methods for coronavirus research, sharing resources...

  5. Cre-ating New Methods for Site-specific Recombination in Drosophila

    Type
    Blog Post
    Published
    May 12, 2015, 1:32 p.m.
    ...from the standard UAS/GAL4 system is toxic to proliferating cells. A Cre-estrogen receptor ligand binding...about new recombinases suitable for this system. Gerald Rubin’s lab sought to make complex genome modifications...specific recombination site for each enzyme, were generated to test recombination efficiency. When expressed...PubMed. Reduction of Cre recombinase toxicity in proliferating Drosophila cells by estrogen-dependent activity...

  6. Celebrating Outstanding CRISPR/Cas9 Achievements at the Dr. Paul Janssen Award Dinner

    Type
    Blog Post
    Published
    Sept. 15, 2014, 6:05 p.m.
    ...and Dr. Paul Stoffels from J&J. The panel was moderated by a non-scientist from Bloomberg news. Given ...who shared first authorship on their seminal, cooperative paper in Science.  Interestingly, this project...finding they have been able to use CRISPR/Cas9 to generate mice with genes knocked out in the insulin signaling..., open academic exploration in this area will accelerate the launch of clinical applications. During ...

  7. London Calling - Addgene’s New Europe Office in London

    Type
    Blog Post
    Published
    June 10, 2014, 3:20 p.m.
    ... brand new Europe office located in London and operated in collaboration with LGC Standards. And now you... VII. During my years in research, I developed several new plasmids, including: plasmids to study the ...and shared by others to develop an anti-tumour therapy using antibodies targeting dendritic cells. These...sharing those ideas with others. This love of interacting with people and talking about science makes her...

  8. Zebrafish as a Model for Behavior: Swimming into the Optogenetic Spotlight

    Type
    Blog Post
    Published
    July 16, 2019, 12:59 p.m.
    ...escape reflex. These traits, coupled with short generation times and high fecundity, make zebrafish ideal...lights (Baier et al., 2009).  Zebrafish behaviors Several behavioral assays can be done on zebrafish at 5...neurons that trigger the CPG (central pattern generator) (Wyart et al., 2009). The CPG is a neural circuit...circuit involved in locomotion that generates periodic motor commands for rhythmic movements like spontaneous...

  9. Running for Rare Disease, Running for FOP, Running for AJ

    Type
    Blog Post
    Published
    Sept. 15, 2016, 2:30 p.m.
    ...receptor ACVR1. ACVR1 triggers appropriate bone regeneration in healthy patients. However, the R206H mutation...including Activin A. A commercially developed therapeutic antibody that binds Activin A and interferes ...interferes with inappropriate activin-ACVR1 interactions prevents FOP bone growth in mouse models. As this biologic...experience is in both vaccine subunit design and therapeutic biologic design (ADCs) along with pre-clinical...

  10. Chemogenetics vs. Optogenetics: Which Method Should I Choose?

    Type
    Blog Post
    Published
    June 11, 2020, 1:34 p.m.
    ...behaviors. Scientists continue to engineer opsins to operate at increasingly faster kinetics. The opsin ChETA...body. Administering the drug once can result in several hours of neuronal excitation or inhibition. This...sustained activation period is beneficial for use in therapeutic or behavioral applications where drawn out effects... by Designer Drugs): Chemogenetic Tools with Therapeutic Utility. Annual Review of Pharmacology and Toxicology...
Showing: 471 - 480 of 837 results