We narrowed to 214 results for: OVA
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TypeBlog PostPublishedApril 20, 2021, 2:30 p.m....achieve a high titer (reviewed in Joglekar and Sandoval, 2017). This high titer is one of the reasons ...https://doi.org/10.3390/v12091016 Joglekar AV, Sandoval S (2017) Pseudotyped Lentiviral Vectors: One Vector...
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What's Your Organism? Expanding Genomic Tools via the NSF EDGE Program
TypeBlog PostPublishedMay 2, 2019, 12:41 p.m....program should “enable the ability to study life’s innovations from anywhere in the tree of life.” Accepted ...manipulation. The ReMOT control system (Receptor-Mediated Ovary Transduction of Cargo) delivers Cas9 RNP to the... -
Designing Your Chalk Talk for the Academic Job Interview
TypeBlog PostPublishedMarch 12, 2019, 1:37 p.m....problem and then explain why it’s significant and innovative. For example, "while it is possible to grow liver... best person to do this research? Do you have innovative tools? A novel dataset? Unique expertise? A novel... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog PostPublishedNov. 19, 2020, 2:15 p.m....co-founded by Kaspar, acquired by Novartis and rebranded to Novartis Gene Therapies, and Taysha Gene Therapies... -
To Codon Optimize or Not: That is the Question
TypeBlog PostPublishedNov. 12, 2020, 2:15 p.m....Optimization References Athey J, Alexaki A, Osipova E, Rostovtsev A, Santana-Quintero LV, Katneni U...Addgene;s dataset reveals trends in biological innovation Resources on Addgene.org Check out Addgene'... -
The PAM Requirement and Expanding CRISPR Beyond SpCas9
TypeBlog PostPublishedAug. 20, 2020, 2:30 p.m....Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F (2015) In vivo... B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der... -
Hot Plasmids - August 2020
TypeBlog PostPublishedAug. 18, 2020, 1:15 p.m....derived either from p63(1-29) and Lck. Image from Chertkova et al., 2020. In their BioRxiv post, the authors...mammalian cell structure markers plasmids at Addgene! Chertkova, AO, et al., bioRxiv. 2020. https://doi.org/10.1101... -
An Integrin Antibody Toolkit from IPI
TypeBlog PostPublishedMarch 28, 2024, 1:15 p.m....inhibited. Recently, we at the Institute for Protein Innovation (IPI), a Boston-based, nonprofit protein research...a science writer at the Institute for Protein Innovation. She writes about all things IPI, from the scientists... -
New Optogenetic Tools for Cytoskeleton and Membrane Control
TypeBlog PostPublishedSept. 28, 2023, 1:15 p.m....are not easily reversible. Late last year, the Akhmanova Lab published a new optogenetic tool for localized...Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool ... -
Evolution of Lab Techniques
TypeBlog PostPublishedJune 21, 2016, 2:30 p.m....papers or are brainstorming new technological innovations. Let’s take a look at three historical techniques...past. In the sequencing world, one up and coming innovation is nanopore-based DNA sequencing which reads ... -
Viral Vectors 101: Systemic Capsids
TypeBlog PostPublishedOct. 12, 2023, 1:15 p.m....throughout the central nervous system. Nature Cardiovascular Research, 1(4), Article 4. https://doi.org/...Gore, B. B., Weed, N., Omstead, V., Bishaw, Y., Shapovalova, N. V., Martinez, R. A., Fong, O., Yao, S., Mortrud... -
Hot Plasmids: Spring 2025
TypeBlog PostPublishedJune 3, 2025, 1:15 p.m....flexibility and speed, so you can design, test, and innovate faster than ever. Plus, we've already taken them...potential. Our partners at the Institute for Protein Innovation (IPI) recently released a set of highly-specific... -
Viral Vectors 101: AAV Variables That Matter
TypeBlog PostPublishedJune 1, 2023, 1:15 p.m....optimizing! Recommended Reading Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. ....org/10.1038/s41434-019-0075-6 Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. ... -
Technologies Enabled by NanoLuc® Luciferase
TypeBlog PostPublishedFeb. 8, 2018, 12:17 p.m.... encourage people to go to Addgene to get new innovative tools. Afterall, isn’t science better when we...fluorescent proteins has allowed researchers to make innovative tools not possible with other luciferases. In... -
Scientific Reproducibility - Focusing on Solutions at the Minisymposium on Reproducibility
TypeBlog PostPublishedMay 18, 2018, 7:32 p.m....Development - Steven C. Almo, Institute for Protein Innovation 1:18:45 - 2:01:18 (end) - Panel Alex Tucker... talk about work at the Institute for Protein Innovation (IPI) (49:45 - 1:18:45), there are also initiatives... -
Easi-CRISPR: Generating Knock-In and Conditional Mouse Models
TypeBlog PostPublishedApril 5, 2018, 12:42 p.m....correctly edited founder. Figure 6: Diagram of ovary and oviduct anatomy with the equipment used for ...female mice using a small incision that exposes the ovaries and oviducts. After solution injection into the... -
Building Global Connections with the International Mentorship Program USA-EUROPE
TypeBlog PostPublishedNov. 6, 2015, 3:30 p.m.... can exchange ideas, network, collaborate, and innovate internationally. Why an International Mentorship...Spanish Secretary of Research, Development, and Innovation, D. Carmen Vela, who reiterated the Spanish government... -
Finding Your Science Policy Path
TypeBlog PostPublishedSept. 22, 2020, 1:15 p.m....who decides how they are going pursue regulatory approval for a new product or a well-endowed philanthropy...interested in driving scientific and technological innovation that is accessible and equitable for all. You... -
Fluorescent Proteins 101: Monitoring Cell Mobility Using Fluorescent Proteins
TypeBlog PostPublishedAug. 15, 2017, 1:24 p.m....sites of infection or damage (Peters et al. 2008, Chtanova et al. 2008, Kamenyeva et al. 2015)? How do blood...18703742. PubMed Central PMCID: PMC2606057. 2. Chtanova, Tatyana, et al. "Dynamics of neutrophil migration... -
Starter Guide to induced Pluripotent Stem Cells (iPSCs) Part 2: Reprogramming and Transdifferentiation
TypeBlog PostPublishedNov. 6, 2018, 1:12 p.m.... vitro and in vivo Epigenetic marks Complete removal to convert to iPSCs and re-establishment after ...PMID: 24302443. 29. Kogut, I., D.R. Roop, and G. Bilousova, Differentiation of human induced pluripotent ...