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Showing: 101 - 120 of 332 results

  1. Make a Splash: Notions of Scientific Impact Are Evolving

    Type
    Blog Post
    Published
    Dec. 5, 2014, 2:54 p.m.
    ...Ventures like Impact Story seek to find ways to capture scholarly work that exists outside of traditional...Of course, no one measure will ever adequately capture a notion as complex as “scientific impact.” As ...

  2. A Scientist's Guide to Ebola

    Type
    Blog Post
    Published
    Oct. 16, 2014, 3:01 p.m.
    ...It’s pretty hard to escape news and fears of Ebola these days, as the infectious disease once limited...described how the glycoprotein transforms itself to escape vesicles within host cells and turn the cell into...

  4. Reflections and Looking Ahead

    Type
    Blog Post
    Published
    Feb. 25, 2025, 2:15 p.m.
    ...scientific gains by adding long-read sequencing capabilities to complement our next-generation sequencing...flourishes when data are shared. The scientific landscape is evolving rapidly, and with it, the needs of...

  5. In Living Color: The Skinny on In Vivo Imaging Tools

    Type
    Blog Post
    Published
    March 27, 2014, 5:14 p.m.
    ...described in Nature Communications last year, “The capability to control spectral properties of PA FPs with...is also looking in the direction of biosensors capable of revealing, for example, how muscles work inside...

  6. CUT&RUN: An Improved Method for Studying Protein-DNA Interactions

    Type
    Blog Post
    Published
    Feb. 13, 2018, 2:51 p.m.
    ...sheering of DNA by sonification. Though it helps capture weaker or more transient DNA-protein interactions...fusion proteins Study chromatin interactions with CAPTURE Additional Resources on Addgene.org Find simple...

  8. Bricking Science: Portraying Scientific Reality Through LEGO

    Type
    Blog Post
    Published
    Nov. 29, 2016, 3:30 p.m.
    ...gnome. See this video where he/she/it/something is captured on camera: Unfortunately, unless they’ve worked...were mirrored by the nearly infinite regulatory capabilities of gene pathways just waiting to be discovered...

  9. Safe Port in a Storm...How Addgene is Weathering the Pandemic

    Type
    Blog Post
    Published
    Sept. 17, 2020, 1:15 p.m.
    .... We don’t raise money except occasionally for capital equipment or resources needed to launch a new service...workforce for when we need to be working at full capacity to serve the scientific community. First, we applied...

  10. Another Pathway into Cells: iTOP

    Type
    Blog Post
    Published
    June 23, 2015, 8:37 p.m.
    ... Primary cells recapitulate the natural biology of a cell type of interest better than immortalized lines...to a protein of interest thereby giving it the capacity to enter cells. One such CPP was discovered in...

  14. Viral Vectors 101: Viral Applications

    Type
    Blog Post
    Published
    April 13, 2023, 1:15 p.m.
    ...the viral titer (the number of viral particles capable of infecting a host cell) can be tuned so that ...Viral vector platforms within the gene therapy landscape. Sig Transduct Target Ther 6, 53 (2021). DOI: ...

  15. Viral Vectors 101: Viruses as Biological Tools

    Type
    Blog Post
    Published
    March 21, 2023, 1:15 p.m.
    ...Expression Infects Non-Dividing Cells Large Packaging Capacity (>8kb) High Transduction Efficiency Transient...Mouse Cells and Hematopoietic Cells Low Packaging Capacity (~4.5kb From basic science to clinical applications...

  17. Clear and Accessible Writing

    Type
    Blog Post
    Published
    Feb. 15, 2024, 2:15 p.m.
    ...densities are captured at the 17%, 25%, and 60% layers, and genome-containing virions are captured at the 40%...

  19. CRISPRainbow and Genome Visualization

    Type
    Blog Post
    Published
    Feb. 28, 2017, 3:30 p.m.
    ...fluorescent in situ hybridization (FISH) and chromosome capture suffer from low resolution and can’t be used in...editing, but it retains its gRNA-directed targeting capacity. By using a gRNA to target fluorescently labeled...

  20. CRISPR 101: Cas9 vs. The Other Cas(s)

    Type
    Blog Post
    Published
    Dec. 8, 2022, 2:15 p.m.
    ... therapeutic delivery by AAV, which has strict capacity limitations. New efforts have recently been made...Cas7 and Cas11 domains. Cas7-11 cuts ssRNA and is capable of pre-crRNA self-processing. Functionally, it ...
Showing: 101 - 120 of 332 results