We narrowed to 333 results for: caps
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TypeBlog PostPublishedDec. 5, 2014, 2:54 p.m....Ventures like Impact Story seek to find ways to capture scholarly work that exists outside of traditional...Of course, no one measure will ever adequately capture a notion as complex as “scientific impact.” As ...
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A Scientist's Guide to Ebola
TypeBlog PostPublishedOct. 16, 2014, 3:01 p.m....It’s pretty hard to escape news and fears of Ebola these days, as the infectious disease once limited...described how the glycoprotein transforms itself to escape vesicles within host cells and turn the cell into... -
Making Career Development an Integral Part of the Science Training System
TypeBlog PostPublishedFeb. 25, 2021, 2:15 p.m....2019 solidified the project and the findings were captured in this just released report “Enhancing Dissemination...of priorities for pd|hub which include building capacity to identify the most effective practices and disseminating... -
Reflections and Looking Ahead
TypeBlog PostPublishedFeb. 25, 2025, 2:15 p.m....scientific gains by adding long-read sequencing capabilities to complement our next-generation sequencing...flourishes when data are shared. The scientific landscape is evolving rapidly, and with it, the needs of... -
In Living Color: The Skinny on In Vivo Imaging Tools
TypeBlog PostPublishedMarch 27, 2014, 5:14 p.m....described in Nature Communications last year, “The capability to control spectral properties of PA FPs with...is also looking in the direction of biosensors capable of revealing, for example, how muscles work inside... -
Bricking Science: Portraying Scientific Reality Through LEGO
TypeBlog PostPublishedNov. 29, 2016, 3:30 p.m....gnome. See this video where he/she/it/something is captured on camera: Unfortunately, unless they’ve worked...were mirrored by the nearly infinite regulatory capabilities of gene pathways just waiting to be discovered... -
CUT&RUN: An Improved Method for Studying Protein-DNA Interactions
TypeBlog PostPublishedFeb. 13, 2018, 2:51 p.m....sheering of DNA by sonification. Though it helps capture weaker or more transient DNA-protein interactions...fusion proteins Study chromatin interactions with CAPTURE Additional Resources on Addgene.org Find simple... -
CASTing Off for New Shores in Human Genome Editing
TypeBlog PostPublishedJune 10, 2025, 1:15 p.m....power of CRISPR combined with the large sequence capacity of transposons open whole new worlds to explore... the course of evolution, Tn7-like transposons captured and repurposed nuclease-deficient CRISPR-Cas systems... -
The Open Repository of CRISPR Screens: CRISPR Screen Data in One Place
TypeBlog PostPublishedJan. 21, 2020, 2:30 p.m..... Importantly, metadata for each screen is captured by BioGRID curators, including the cell line/tissue...determine the gene hits for each screen are also captured as metadata. Screen results are reported as ... -
Safe Port in a Storm...How Addgene is Weathering the Pandemic
TypeBlog PostPublishedSept. 17, 2020, 1:15 p.m..... We don’t raise money except occasionally for capital equipment or resources needed to launch a new service...workforce for when we need to be working at full capacity to serve the scientific community. First, we applied... -
Another Pathway into Cells: iTOP
TypeBlog PostPublishedJune 23, 2015, 8:37 p.m.... Primary cells recapitulate the natural biology of a cell type of interest better than immortalized lines...to a protein of interest thereby giving it the capacity to enter cells. One such CPP was discovered in... -
Addgene’s Viral Service - Why Virus? Why Now?
TypeBlog PostPublishedMarch 23, 2017, 2:30 p.m....sponsored the capital construction of our new BL2+ laboratory and the infrastructure capabilities to produce... -
Hot Plasmids December 2018 - C. elegans RNAi, TurboID, Detecting Viral Outbreaks, and Protein Binding Specificity Tools
TypeBlog PostPublishedDec. 6, 2018, 1:34 p.m.... money, and viruses at low concentrations often escape detection. The Alexander Green lab found a solution...University of Toronto expanded the specificity landscape of the SH3 proteins using peptide-phage display... -
Cas13d: Small RNA-targeting CRISPR enzymes for transcriptome engineering
TypeBlog PostPublishedMay 3, 2018, 1:48 p.m.... 2.8 kb in size and are easy to package in low-capacity vectors! These small, but mighty type VI-D enzymes...Their small size makes then easy to package in low-capacity vectors like AAV, a popular vector due to its ... -
Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog PostPublishedMarch 17, 2020, 1:32 p.m....been trying to expand their precision editing capabilities. Base editors make specific DNA base changes...development towards faster and more precise base editors capable of editing previously uneditable sequences. Four... -
Viral Vectors 101: Viral Applications
TypeBlog PostPublishedApril 13, 2023, 1:15 p.m....the viral titer (the number of viral particles capable of infecting a host cell) can be tuned so that ...Viral vector platforms within the gene therapy landscape. Sig Transduct Target Ther 6, 53 (2021). DOI: ... -
Viral Vectors 101: Viruses as Biological Tools
TypeBlog PostPublishedMarch 21, 2023, 1:15 p.m....Expression Infects Non-Dividing Cells Large Packaging Capacity (>8kb) High Transduction Efficiency Transient...Mouse Cells and Hematopoietic Cells Low Packaging Capacity (~4.5kb From basic science to clinical applications... -
Clear and Accessible Writing
TypeBlog PostPublishedFeb. 15, 2024, 2:15 p.m....densities are captured at the 17%, 25%, and 60% layers, and genome-containing virions are captured at the 40%... -
Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur
TypeBlog PostPublishedJuly 10, 2014, 7:17 p.m....Flagship Ventures – a local Cambridge biotech venture capital firm with deep ties into the local academic community...Drug by Barry Werth Ten Tips for Raising Startup Capital in Biotech - Posted on Forbes.com, contributed... -
Announcing the Winners of the 2021 Michael Davidson and Roger Tsien Commemorative Conference Awards
TypeBlog PostPublishedAug. 5, 2021, 12:15 p.m....enzyme hydropersulfide-propagating enzymes 3-mercaptopyruvate sulfurtransferase (MPST) which catalyzes the... the desulfuration of 3-mercaptopyruvate and generates an enzyme-bound hydropersulfide that is then transferred...