Skip to main content
Addgene
Showing: 1 - 6 of 6 results
  1. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    Published
    May 18, 2023, 1:15 p.m.
    ...complement deposition (ADCD) b) antibody-dependent cellular cytotoxicity (ADCC) c) antibody-dependent ...dependent cellular cytotoxicity (ADCC) Antibody dependent cellular cytotoxicity (ADCC) is a slightly more direct...antibody-dependent cellular phagocytosis (ADCP). Figure adapted from van Erp, et al., 2019.    Antibody-dependent complement... complement deposition (ADCD) Antibodies can bind to a pathogen and physically prevent it from entering...opsonization. In antibody-dependent complement deposition (ADCD), opsonization of IgG and IgM antibodies on a pathogen...direct method than opsonization. In ADCC, IgG antibodies bind to a pathogen and natural killer (NK) cells...target cell. If the pathogen is a large parasite, ADCC can be induced through a very similar interaction...
  2. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    Published
    Feb. 13, 2025, 2:15 p.m.
    ...Neugebauer et al., 2023 TadCBE, TadDE   Evolved TadA domain for cytosine base editing (TadCBE) or dual cytosine... 2023). These CBEs (called Td-CBEs, CBE-Ts, or TadCBEs) are smaller and less likely to cause off-target...
  3. Anatomy of a Plasmid Page at Addgene

    Type
    Blog Post
    Published
    Feb. 4, 2016, 3:30 p.m.
    ...your colleagues. Top of the plasmid page The ‘breadcrumb’ trail at the top of any plasmid page gives the...
  4. CRISPR 101: Off-Target Effects

    Type
    Blog Post
    Published
    Feb. 8, 2024, 2:15 p.m.
    ... where nicking/cleaving of DNA occurs, not for deadCas activator/repressor experiments where only localization...
Showing: 1 - 6 of 6 results