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We narrowed to 6 results for: ADC

Showing: 1 - 6 of 6 results
  1. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    Published
    May 18, 2023, 1:15 p.m.
    ...complement deposition (ADCD) b) antibody-dependent cellular cytotoxicity (ADCC) c) antibody-dependent ...dependent cellular cytotoxicity (ADCC) Antibody dependent cellular cytotoxicity (ADCC) is a slightly more direct...antibody-dependent cellular phagocytosis (ADCP). Figure adapted from van Erp, et al., 2019.    Antibody-dependent complement... complement deposition (ADCD) Antibodies can bind to a pathogen and physically prevent it from entering...opsonization. In antibody-dependent complement deposition (ADCD), opsonization of IgG and IgM antibodies on a pathogen...direct method than opsonization. In ADCC, IgG antibodies bind to a pathogen and natural killer (NK) cells...target cell. If the pathogen is a large parasite, ADCC can be induced through a very similar interaction...
  2. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    Published
    Feb. 13, 2025, 2:15 p.m.
    ...Neugebauer et al., 2023 TadCBE, TadDE   Evolved TadA domain for cytosine base editing (TadCBE) or dual cytosine...base editing (TadDE) Wu et al., 2025 TadCBE(NCN) variants, TadCABE   Evolved TadA domain for position-specific...cytosine base editing (TadCBE variants) or dual cytosine and adenine base editing (TadCABE) This post was... 2023). These CBEs (called Td-CBEs, CBE-Ts, or TadCBEs) are smaller and less likely to cause off-target...adenine base editing, called CABE-Ts, TadDEs, or TadCABEs, without additional fused components (Lam et al...
  3. Anatomy of a Plasmid Page at Addgene

    Type
    Blog Post
    Published
    Feb. 4, 2016, 3:30 p.m.
    ...your colleagues. Top of the plasmid page The ‘breadcrumb’ trail at the top of any plasmid page gives the...
  4. CRISPR 101: Off-Target Effects

    Type
    Blog Post
    Published
    Feb. 8, 2024, 2:15 p.m.
    ... where nicking/cleaving of DNA occurs, not for deadCas activator/repressor experiments where only localization...
Showing: 1 - 6 of 6 results