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Showing: 1 - 9 of 9 results

  2. Antibodies 101: Fc Effector Functions

    Type
    Blog Post
    ...complement deposition (ADCD) b) antibody-dependent cellular cytotoxicity (ADCC) c) antibody-dependent ...dependent cellular cytotoxicity (ADCC) Antibody dependent cellular cytotoxicity (ADCC) is a slightly more direct...antibody-dependent cellular phagocytosis (ADCP). Figure adapted from van Erp, et al., 2019.    Antibody-dependent complement... complement deposition (ADCD) Antibodies can bind to a pathogen and physically prevent it from entering...opsonization. In antibody-dependent complement deposition (ADCD), opsonization of IgG and IgM antibodies on a pathogen...direct method than opsonization. In ADCC, IgG antibodies bind to a pathogen and natural killer (NK) cells...target cell. If the pathogen is a large parasite, ADCC can be induced through a very similar interaction...

  3. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    ...Neugebauer et al., 2023 TadCBE, TadDE   Evolved TadA domain for cytosine base editing (TadCBE) or dual cytosine... 2023). These CBEs (called Td-CBEs, CBE-Ts, or TadCBEs) are smaller and less likely to cause off-target...

  6. CRISPR 101: Off-Target Effects

    Type
    Blog Post
    ... where nicking/cleaving of DNA occurs, not for deadCas activator/repressor experiments where only localization...

  7. Empty Backbones - Choosing Your Perfect Plasmid Backbone

    Type
    Collection
    ...that adds a C-terminal nuclear localization signal pGADCg - Gateway yeast expression vector that adds a SV40... pGADT7-GW - Gateway compatible Y2H vector - AD pGADCg - Gateway compatible Y2H vector BASTA Plant pGTQL1211YN...
Showing: 1 - 9 of 9 results