We narrowed to 5 results for: Dnmt3a

1. CRISPR 101: Epigenetics and Editing the Epigenome

   Type

   Blog Post

   Published

   June 24, 2020, 5:45 p.m.

   ...Methyltransferase 3 Alpha (DNMT3A) Vlatka Zoldoš’ lab has deposited pdCas9-DNMT3A-EGFP and pdCas9-DNMT3A-PuroR for targeted...For lentiviral expression, Fuw-dCas9-Dnmt3a and Fuw-dCas9-Dnmt3a-P2A-tagBFP are available from Rudolf ...ready-to-use lentivirus. Figure 3: dCas9-DNMT3A methylates cytosines at promoters and enhancers...transient and quickly reversed in culture. However, DNMT3A-induced methylation persisted throughout a 100 ...

2. New CRISPR Web Resources and #12DaysofCRISPR Recap

   Type

   Blog Post

   Published

   Dec. 12, 2017, 3:13 p.m.

   ... demethylation by LSD1, cytosine methylation by DNMT3A or MQ1, and cytosine demethylation by Tet1. RNA...

3. Simple CRISPR-based Epigenetic Editing: dCas9-directed DNA Demethylation

   Type

   Blog Post

   Published

   Dec. 14, 2021, 2:15 p.m.

   ...acetyltransferase p300 or the DNA methyltransferase DNMT3A allows researchers to easily add biochemical marks...

4. Hot Plasmids: Summer 2024

   Type

   Blog Post

   Published

   Aug. 27, 2024, 1:15 p.m.

   ...the endogenous, autoinhibited methyltransferase DNMT3A to the genomic location specified by the DNA-binding...

5. 27 Hot Plasmids from 2016

   Type

   Blog Post

   Published

   Dec. 22, 2016, 3:03 p.m.

   ...the catalytic domain from DNA methyltransferase, DNMT3A. Co-expression of this modified Cas9 along with...