We narrowed to 10 results for: keith joung
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TypeBlog PostPublishedAug. 20, 2020, 2:30 p.m....pyogenes Cas9s with novel PAM recognition In 2015, Keith Joung’s lab performed a series of positive selection...Abudayyeh OO, Gootenberg JS, Essletzbichler P, Han S, Joung J, Belanto JJ, Verdine V, Cox DBT, Kellner MJ, Regev...Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F (2017) RNA editing with CRISPR-Cas13....Gonzales APW, Li Z, Peterson RT, Yeh J-RJ, Aryee MJ, Joung JK (2015) Engineered CRISPR-Cas9 nucleases with ...Nguyen NT, Welch MM, Lopez JM, McCaw ZR, Aryee MJ, Joung JK (2016) Genome-wide specificities of CRISPR-Cas...Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F (...
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What's New in CRISPR - May 2019
TypeBlog PostPublishedMay 28, 2019, 12:49 p.m.... unwanted RNA editing (SECURE) base editors Keith Joung’s lab recently found that a cytosine base editor... -
What's New in CRISPR - December 2019
TypeBlog PostPublishedDec. 17, 2019, 2:37 p.m....SECURE adenine base editor Earlier this year, Keith Joung’s lab developed SECURE cytosine base editors, ... -
Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity
TypeBlog PostPublishedNov. 5, 2019, 1:28 p.m....Feng Zhang Lab had described eSpCas9, while the Keith Joung Lab had developed SpCas9-HF1. Both of the enzymes...off-target activity relative to Cas9. Since then, the Joung and Jennifer Doudna Labs used targeted mutagenesis... -
Addgene @ Keystone: Thoughts on Precision Genome Engineering and Synbio
TypeBlog PostPublishedJan. 15, 2015, 1:50 p.m....CRISPR-Cas9 field – Jennifer Doudna, Feng Zhang, and Keith Joung. All Addgene depositors! Addgene was mentioned... -
Sequencing Options for CRISPR Genotyping
TypeBlog PostPublishedOct. 4, 2016, 2:30 p.m....PMCID: PMC3651036. 15. Tsai, Shengdar Q., and J. Keith Joung. "Defining and improving the genome-wide specificities...genotyping options. Figure reproduced from Tsai and Joung 2016 with permission. Even though progress has...experiments move closer to the clinic (Tsai and Joung 2016). Table 2: Unbiased Genotyping Options Technique...specificities of CRISPR–Cas9 nucleases” by Tsai and Joung 2016. Many thanks to our guest blogger Søren Hough... -
Hot Plasmids and Viral Preps - March 2021
TypeBlog PostPublishedMarch 23, 2021, 1:15 p.m....resistance markers. New CRISPR pooled library from Keith Joung’s and Benjamin Kleinstiver’s labs are now available... -
Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog PostPublishedNov. 19, 2020, 2:15 p.m....Investigators and Addgene depositors David Liu, PhD, Keith Joung, PhD, and Feng Zhang, PhD, is pursuing CRISPR... -
CRISPR 101: Cytosine Transversion Editors
TypeBlog PostPublishedMarch 25, 2025, 1:15 p.m....transversion editors starts with researchers in the Keith Joung lab, who were engineering an ABE to reduce its...Miller, B. R., Langner, L. M., Grünewald, J., & Joung, J. K. (2021). CRISPR C-to-G base editors for inducing... -
CRISPR 101: Cytosine and Adenine Base Editors
TypeBlog PostPublishedFeb. 13, 2025, 2:15 p.m....adenine and cytosine editing components together. Keith Joung’s lab created a dual-deaminase editor called SPACE...R., Langner, L. M., Hsu, J. Y., Aryee, M. J., & Joung, J. K. (2020). A dual-deaminase CRISPR base editor...