Hot Biosensors 2022: Year-End Roundup
Type
Blog Post
Published
Dec. 6, 2022, 2:15 p.m.
...biosensors new to Addgene this year.
Feel the love with MTRIA sensors
One of the latest additions to Addgene’s...TRansmembrane region-to-IntrAcellular loop linkers” (MTRIA for short), where a fluorescent protein is inserted... ligand (Ino et al. 2022). The oxytocin sensor MTRIAOT enabled real-time observations of oxytocin dynamics...earlier tools. They also produce more than 20 other MTRIA sensors based on GPCRs recognizing various neurotransmitters...ligands - almost A to Z! - from ATP to urotensin. The MTRIA sensors will be useful for investigating neuronal...sensors for these and other targets.
Figure 1: MTRIA biosensors are generated by inserting a circularly-permuted...from Ino et al. 2022, under CC-BY license.
Find MTRIA sensors here!
Ino D, et al. A fluorescent sensor...