CRISPR Guide
Type
Guide
...base editors (pyrimidine-to-pyrimidine), which catalyze base transitions. Cytosine base editors are created...The TadA domain has also been further evolved to catalyze cytidine deamination instead of (or in addition...researchers have developed base editors that can catalyze base transversions. These editors are based on...C-terminus of Cas9 H840A nickase. The fusion enzyme can catalyze targeted insertions, deletions, and all possible...