Adenovirus Guide
Type
Guide
...production of replication-competent adenoviruses (RCAs) that would be able to infect cells and replicate...production, and higher titers. However, the risk of RCA formation is higher for first-generation rAdV vectors...exposed. There is a risk of spontaneous reversion to RCAs, although this has been reduced by providing the...adenovirus and replication-competent adenovirus (RCA) contaminants . Experimental & Molecular Medicine...material into cells. Replication-competent adenovirus (RCA) Mutated adenoviral vector that has the ability to...