CRISPR Guide
Type
Guide
...such as dCas9-KRAB) or dCas9 gRNA(s) targeting promoter elements of target gene dCas9-KRAB is more effective...transcriptional activator (e.g. VP64) or repressor (e.g. KRAB; see panel A to the right). Additionally, more elaborate...Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna...