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Fuw-dCas9-Tet1CD-P2A-BFP Citations (6)

Originally described in: Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.
Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R Cell. 2018 Feb 8. pii: S0092-8674(18)30049-7. doi: 10.1016/j.cell.2018.01.012.
PubMed Journal

Articles Citing Fuw-dCas9-Tet1CD-P2A-BFP

Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons. Graef JD, Wu H, Ng C, Sun C, Villegas V, Qadir D, Jesseman K, Warren ST, Jaenisch R, Cacace A, Wallace O. Eur J Neurosci. 2020 May;51(10):2143-2157. doi: 10.1111/ejn.14660. Epub 2020 Feb 4. PubMed
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. Halmai JANM, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FKB, Waldo JJ, Lock SR, Anderson JD, O'Geen H, Segal DJ, Nolta J, Fink KD. Nucleic Acids Res. 2020 Mar 18;48(5):2372-2387. doi: 10.1093/nar/gkz1214. PubMed
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. PubMed
p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino. Marney CB, Anderson ES, Adnan M, Peng KL, Hu Y, Weinhold N, Schmitt AM. Cell Rep. 2021 Jun 29;35(13):109329. doi: 10.1016/j.celrep.2021.109329. PubMed
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9. Sapozhnikov DM, Szyf M. Nat Commun. 2021 Sep 29;12(1):5711. doi: 10.1038/s41467-021-25991-9. PubMed

Associated Plasmids

CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells. Wilk C, Effenberg L, Abberger H, Steenpass L, Hansen W, Zeschnigk M, Kirschning C, Buer J, Kehrmann J. Cell Immunol. 2022 Jan;371:104471. doi: 10.1016/j.cellimm.2021.104471. Epub 2021 Dec 20. PubMed

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