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pBABE-bleo IGF-1R Citations (13)

Originally described in: Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.
Entingh-Pearsall A, Kahn CR J Biol Chem. 2004 Sep 3. 279(36):38016-24.
PubMed Journal

Articles Citing pBABE-bleo IGF-1R

Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells. Marconett CN, Singhal AK, Sundar SN, Firestone GL. Mol Cell Endocrinol. 2012 Nov 5;363(1-2):74-84. doi: 10.1016/j.mce.2012.07.008. Epub 2012 Jul 24. PubMed
Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy. Wang Q, Ru Y, Zhong D, Zhang J, Yao L, Li X. Oncotarget. 2014 Jul 15;5(13):4945-58. PubMed
FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells. Taliaferro-Smith L, Oberlick E, Liu T, McGlothen T, Alcaide T, Tobin R, Donnelly S, Commander R, Kline E, Nagaraju GP, Havel L, Marcus A, Nahta R, O'Regan R. Oncotarget. 2015 Mar 10;6(7):4757-72. PubMed
IGF-1 Receptor Modulates FoxO1-Mediated Tamoxifen Response in Breast Cancer Cells. Vaziri-Gohar A, Zheng Y, Houston KD. Mol Cancer Res. 2017 Apr;15(4):489-497. doi: 10.1158/1541-7786.MCR-16-0176. Epub 2017 Jan 17. PubMed
Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers. Rajbhandari N, Lin WC, Wehde BL, Triplett AA, Wagner KU. Cell Rep. 2017 Feb 28;18(9):2243-2255. doi: 10.1016/j.celrep.2017.02.013. PubMed
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Chen LM, Chai KX. Oncotarget. 2017 Apr 10;8(34):56490-56505. doi: 10.18632/oncotarget.17009. eCollection 2017 Aug 22. PubMed
Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane. Werbin JL, Avendano MS, Becker V, Jungmann R, Yin P, Danuser G, Sorger PK. Sci Rep. 2017 Sep 22;7(1):12150. doi: 10.1038/s41598-017-12257-y. PubMed
Copper Chelation Inhibits BRAF(V600E)-Driven Melanomagenesis and Counters Resistance to BRAF(V600E) and MEK1/2 Inhibitors. Brady DC, Crowe MS, Greenberg DN, Counter CM. Cancer Res. 2017 Nov 15;77(22):6240-6252. doi: 10.1158/0008-5472.CAN-16-1190. Epub 2017 Oct 6. PubMed
Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming FJ, Trung MT, Meng L, Latreille E, Tanese de Souza C, McCulloch D, Baldwin RM, Auer R, Cote J, Russell RC, Sadoul R, Gibbings D. Dev Cell. 2017 Dec 18;43(6):716-730.e7. doi: 10.1016/j.devcel.2017.11.018. PubMed
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia. Aries IM, Bodaar K, Karim SA, Chonghaile TN, Hinze L, Burns MA, Pfirrmann M, Degar J, Landrigan JT, Balbach S, Peirs S, Menten B, Isenhart R, Stevenson KE, Neuberg DS, Devidas M, Loh ML, Hunger SP, Teachey DT, Rabin KR, Winter SS, Dunsmore KP, Wood BL, Silverman LB, Sallan SE, Van Vlierberghe P, Orkin SH, Knoechel B, Letai AG, Gutierrez A. J Exp Med. 2018 Nov 7. pii: jem.20180570. doi: 10.1084/jem.20180570. PubMed

Associated Plasmids

Anti-edema and antioxidant combination therapy for ischemic stroke via glyburide-loaded betulinic acid nanoparticles. Deng G, Ma C, Zhao H, Zhang S, Liu J, Liu F, Chen Z, Chen AT, Yang X, Avery J, Zou P, Du F, Lim KP, Holden D, Li S, Carson RE, Huang Y, Chen Q, Kimberly WT, Simard JM, Sheth KN, Zhou J. Theranostics. 2019 Sep 21;9(23):6991-7002. doi: 10.7150/thno.35791. eCollection 2019. PubMed
PSPC1 Potentiates IGF1R Expression to Augment Cell Adhesion and Motility. Jen HW, Gu DL, Lang YD, Jou YS. Cells. 2020 Jun 18;9(6). pii: cells9061490. doi: 10.3390/cells9061490. PubMed
PKM2 Regulates HSP90-Mediated Stability of the IGF-1R Precursor Protein and Promotes Cancer Cell Survival during Hypoxia. Koo H, Byun S, Seo J, Jung Y, Lee DC, Cho JH, Park YS, Yeom YI, Park KC. Cancers (Basel). 2021 Jul 30;13(15). pii: cancers13153850. doi: 10.3390/cancers13153850. PubMed

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