pLentiRNAGuide_001 - hU6-RfxCas13d-DR1-BsmBI-EFS-Puro-WPRE Citations (10)
Originally described in: Massively parallel Cas13 screens reveal principles for guide RNA design.Wessels HH, Mendez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE Nat Biotechnol. 2020 Jun;38(6):722-727. doi: 10.1038/s41587-020-0456-9. Epub 2020 Mar 16. PubMed Journal
Articles Citing pLentiRNAGuide_001 - hU6-RfxCas13d-DR1-BsmBI-EFS-Puro-WPRE
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| NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia. Witkowski MT, Lee S, Wang E, Lee AK, Talbot A, Ma C, Tsopoulidis N, Brumbaugh J, Zhao Y, Roberts KG, Hogg SJ, Nomikou S, Ghebrechristos YE, Thandapani P, Mullighan CG, Hochedlinger K, Chen W, Abdel-Wahab O, Eyquem J, Aifantis I. Nat Immunol. 2022 Oct;23(10):1424-1432. doi: 10.1038/s41590-022-01314-y. Epub 2022 Sep 22. PubMed |
| circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment. Piras R, Ko EY, Barrett C, De Simone M, Lin X, Broz MT, Tessaro FHG, Castillo-Martin M, Cordon-Cardo C, Goodridge HS, Di Vizio D, Batish M, Lawrenson K, Chen YG, Chan KS, Guarnerio J. Nat Commun. 2022 Nov 25;13(1):7243. doi: 10.1038/s41467-022-34872-8. PubMed |
| CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression. Noviello G, Gjaltema RAF, Schulz EG. Nat Commun. 2023 Jun 3;14(1):3225. doi: 10.1038/s41467-023-38909-4. PubMed |
| PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis. Ren S, Bai F, Schnell V, Stanko C, Ritsch M, Schenk T, Barth E, Marz M, Wang B, Pei XH, Bierhoff H. Cell Rep. 2024 Jan 23;43(1):113644. doi: 10.1016/j.celrep.2023.113644. Epub 2024 Jan 4. PubMed |
Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx.
Montero JJ, Trozzo R, Sugden M, Ollinger R, Belka A, Zhigalova E, Waetzig P, Engleitner T, Schmidt-Supprian M, Saur D, Rad R.
Nat Methods. 2024 Feb 26. doi: 10.1038/s41592-024-02190-0.
PubMed
Associated Plasmids |
CRISPR-dCas13d-based deep screening of proximal and distal splicing-regulatory elements.
Recinos Y, Ustianenko D, Yeh YT, Wang X, Jacko M, Yesantharao LV, Wu Q, Zhang C.
Nat Commun. 2024 May 7;15(1):3839. doi: 10.1038/s41467-024-47140-8.
PubMed
Associated Plasmids |
Lineage-specific splicing regulation of MAPT gene in the primate brain.
Recinos Y, Bao S, Wang X, Phillips BL, Yeh YT, Weyn-Vanhentenryck SM, Swanson MS, Zhang C.
Cell Genom. 2024 Jun 12;4(6):100563. doi: 10.1016/j.xgen.2024.100563. Epub 2024 May 20.
PubMed
Associated Plasmids |
Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25.
Li JD, Taipale M, Blencowe BJ.
Mol Cell. 2024 Jul 11;84(13):2573-2589.e5. doi: 10.1016/j.molcel.2024.05.028. Epub 2024 Jun 24.
PubMed
Associated Plasmids |
| Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Shembrey C, Yang R, Casan J, Hu W, Chen H, Singh GJ, Sadras T, Prasad K, Shortt J, Johnstone RW, Trapani JA, Ekert PG, Fareh M. Sci Adv. 2024 Dec 20;10(51):eadl0731. doi: 10.1126/sciadv.adl0731. Epub 2024 Dec 18. PubMed |
| Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers. Caragine CM, Le VT, Mustafa M, Diaz BJ, Morris JA, Muller S, Mendez-Mancilla A, Geller E, Liscovitch-Brauer N, Sanjana NE. Nat Commun. 2025 Feb 13;16(1):1611. doi: 10.1038/s41467-025-56568-5. PubMed |
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